monensin-2580 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the monensin-2580 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ACTN2 actinin, alpha 2
AGER advanced glycosylation end product-specific receptor
AMH anti-Mullerian hormone
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BIRC3 baculoviral IAP repeat containing 3
C4BPA complement component 4 binding protein, alpha
CD83 CD83 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRND cholinergic receptor, nicotinic, delta (muscle)
CLCA1 chloride channel accessory 1
CLMN calmin (calponin-like, transmembrane)
COL19A1 collagen, type XIX, alpha 1
COL8A1 collagen, type VIII, alpha 1
CTAGE9 CTAGE family, member 9
CTSE cathepsin E
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAPK2 death-associated protein kinase 2
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DUSP26 dual specificity phosphatase 26 (putative)
EGFR epidermal growth factor receptor
EGR2 early growth response 2
EMP1 epithelial membrane protein 1
EPAS1 endothelial PAS domain protein 1
ESR1 estrogen receptor 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GJA4 gap junction protein, alpha 4, 37kDa
GPC1 glypican 1
GPNMB glycoprotein (transmembrane) nmb
GRK5 G protein-coupled receptor kinase 5
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HCAR3 hydroxycarboxylic acid receptor 3
HNF1B HNF1 homeobox B
IER3 immediate early response 3
IFI30 interferon, gamma-inducible protein 30
IL27RA interleukin 27 receptor, alpha
IL5RA interleukin 5 receptor, alpha
JAK3 Janus kinase 3
KRT1 keratin 1, type II
KYNU kynureninase
LAMA4 laminin, alpha 4
LARP7 La ribonucleoprotein domain family, member 7
LPAR1 lysophosphatidic acid receptor 1
MAPT microtubule-associated protein tau
MMP19 matrix metallopeptidase 19
MSRB2 methionine sulfoxide reductase B2
MTUS1 microtubule associated tumor suppressor 1
MVP major vault protein
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLRP1 NLR family, pyrin domain containing 1
NMUR1 neuromedin U receptor 1
NOV nephroblastoma overexpressed
NR4A1 nuclear receptor subfamily 4, group A, member 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PAEP progestagen-associated endometrial protein
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PARD3 par-3 family cell polarity regulator
PCDHB17P protocadherin beta 17 pseudogene
PDZRN4 PDZ domain containing ring finger 4
PHACTR1 phosphatase and actin regulator 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
POU6F2 POU class 6 homeobox 2
PPP5C protein phosphatase 5, catalytic subunit
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PSG11 pregnancy specific beta-1-glycoprotein 11
PTGER4 prostaglandin E receptor 4 (subtype EP4)
REC8 REC8 meiotic recombination protein
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS1 regulator of G-protein signaling 1
RGS13 regulator of G-protein signaling 13
RGS4 regulator of G-protein signaling 4
RPL23AP32 ribosomal protein L23a pseudogene 32
SCEL sciellin
SCN11A sodium channel, voltage gated, type XI alpha subunit
SCN2B sodium channel, voltage gated, type II beta subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SGK1 serum/glucocorticoid regulated kinase 1
SLAMF7 SLAM family member 7
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC35F6 solute carrier family 35, member F6
SNN stannin
SPTB spectrin, beta, erythrocytic
SQSTM1 sequestosome 1
STARD13 StAR-related lipid transfer (START) domain containing 13
SYNDIG1 synapse differentiation inducing 1
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TIMP3 TIMP metallopeptidase inhibitor 3
TMOD1 tropomodulin 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAF1 TNF receptor-associated factor 1
TRBC1 T cell receptor beta constant 1
TRIM62 tripartite motif containing 62
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
VAC14 Vac14 homolog (S. cerevisiae)
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF646 zinc finger protein 646

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGRE2 adhesion G protein-coupled receptor E2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ART1 ADP-ribosyltransferase 1
ASPN asporin
ATAD5 ATPase family, AAA domain containing 5
BAG4 BCL2-associated athanogene 4
BCORL1 BCL6 corepressor-like 1
BIK BCL2-interacting killer (apoptosis-inducing)
BTNL3 butyrophilin-like 3
CABP2 calcium binding protein 2
CD38 CD38 molecule
CDA cytidine deaminase
CDHR2 cadherin-related family member 2
CFAP69 cilia and flagella associated protein 69
CLIP2 CAP-GLY domain containing linker protein 2
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPNE7 copine VII
CRYGC crystallin, gamma C
CTSO cathepsin O
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
ELSPBP1 epididymal sperm binding protein 1
FAM86C1 family with sequence similarity 86, member C1
FBP1 fructose-1,6-bisphosphatase 1
FBXO31 F-box protein 31
FGF6 fibroblast growth factor 6
FOXN2 forkhead box N2
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAS6 growth arrest-specific 6
GID4 GID complex subunit 4
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR3 G protein-coupled receptor 3
GPR68 G protein-coupled receptor 68
GSTCD glutathione S-transferase, C-terminal domain containing
GSTT1 glutathione S-transferase theta 1
HAMP hepcidin antimicrobial peptide
HIST1H2BJ histone cluster 1, H2bj
HIST1H3I histone cluster 1, H3i
HSPA2 heat shock 70kDa protein 2
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JAM3 junctional adhesion molecule 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0319L KIAA0319-like
KIAA1024 KIAA1024
KIAA1456 KIAA1456
KLF1 Kruppel-like factor 1 (erythroid)
LIG4 ligase IV, DNA, ATP-dependent
LRRC6 leucine rich repeat containing 6
LTBP3 latent transforming growth factor beta binding protein 3
MARC1 mitochondrial amidoxime reducing component 1
MBNL3 muscleblind-like splicing regulator 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
NR1H3 nuclear receptor subfamily 1, group H, member 3
OCEL1 occludin/ELL domain containing 1
OVGP1 oviductal glycoprotein 1, 120kDa
PAIP2B poly(A) binding protein interacting protein 2B
PDGFD platelet derived growth factor D
PER3 period circadian clock 3
PLA2G1B phospholipase A2, group IB (pancreas)
PLSCR4 phospholipid scramblase 4
PPT2 palmitoyl-protein thioesterase 2
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB13 RAB13, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RAB40A RAB40A, member RAS oncogene family
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPL13P5 ribosomal protein L13 pseudogene 5
SALL2 spalt-like transcription factor 2
SCAMP5 secretory carrier membrane protein 5
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SETD8 SET domain containing (lysine methyltransferase) 8
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A4RG SLC2A4 regulator
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPATA1 spermatogenesis associated 1
SYNJ2BP synaptojanin 2 binding protein
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TMEM242 transmembrane protein 242
TPM3 tropomyosin 3
TRAIP TRAF interacting protein
UPK3A uroplakin 3A
VWA1 von Willebrand factor A domain containing 1
WDR33 WD repeat domain 33
ZNF696 zinc finger protein 696