monensin-3704 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the monensin-3704 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AIM2 absent in melanoma 2
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ATN1 atrophin 1
C3 complement component 3
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CCNG2 cyclin G2
CDK10 cyclin-dependent kinase 10
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLTCL1 clathrin, heavy chain-like 1
COBLL1 cordon-bleu WH2 repeat protein-like 1
CSF1R colony stimulating factor 1 receptor
CXCL2 chemokine (C-X-C motif) ligand 2
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DESI2 desumoylating isopeptidase 2
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPP4 dipeptidyl-peptidase 4
DTNB dystrobrevin, beta
ECE1 endothelin converting enzyme 1
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
EFNA1 ephrin-A1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM168A family with sequence similarity 168, member A
FGF2 fibroblast growth factor 2 (basic)
FLJ20712 uncharacterized FLJ20712
FLT1 fms-related tyrosine kinase 1
GK glycerol kinase
GPR161 G protein-coupled receptor 161
GRB10 growth factor receptor-bound protein 10
GTPBP2 GTP binding protein 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HHAT hedgehog acyltransferase
HMOX1 heme oxygenase 1
HN1L hematological and neurological expressed 1-like
HNMT histamine N-methyltransferase
HOMER3 homer scaffolding protein 3
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL37 interleukin 37
INADL InaD-like (Drosophila)
INSIG1 insulin induced gene 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCTD14 potassium channel tetramerization domain containing 14
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
KLHL28 kelch-like family member 28
KRIT1 KRIT1, ankyrin repeat containing
KRT15 keratin 15, type I
KRT34 keratin 34, type I
LAMP1 lysosomal-associated membrane protein 1
LDLR low density lipoprotein receptor
LPIN1 lipin 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MARS methionyl-tRNA synthetase
MEF2D myocyte enhancer factor 2D
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NOV nephroblastoma overexpressed
NPC1 Niemann-Pick disease, type C1
NUPR1 nuclear protein, transcriptional regulator, 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PLXND1 plexin D1
PPIAL4A peptidylprolyl isomerase A (cyclophilin A)-like 4A
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRKCA protein kinase C, alpha
PRTN3 proteinase 3
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAD50 RAD50 homolog (S. cerevisiae)
RNASE4 ribonuclease, RNase A family, 4
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC24D SEC24 family member D
SH2D3A SH2 domain containing 3A
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLMO1 slowmo homolog 1 (Drosophila)
SOX15 SRY (sex determining region Y)-box 15
SPHK2 sphingosine kinase 2
SPN sialophorin
SQLE squalene epoxidase
SQSTM1 sequestosome 1
STC2 stanniocalcin 2
T T, brachyury homolog (mouse)
TAT tyrosine aminotransferase
TMPRSS15 transmembrane protease, serine 15
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TPP1 tripeptidyl peptidase I
TRIB3 tribbles pseudokinase 3
TRIO trio Rho guanine nucleotide exchange factor
WRNIP1 Werner helicase interacting protein 1
XBP1 X-box binding protein 1
ZNF165 zinc finger protein 165
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPHD1 aspartate beta-hydroxylase domain containing 1
BDKRB1 bradykinin receptor B1
BMP4 bone morphogenetic protein 4
C17ORF80 chromosome 17 open reading frame 80
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CAMK4 calcium/calmodulin-dependent protein kinase IV
CD101 CD101 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD70 CD70 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CD80 CD80 molecule
CEL carboxyl ester lipase
CHRDL1 chordin-like 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLEC4E C-type lectin domain family 4, member E
CNTFR ciliary neurotrophic factor receptor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNM3 dynamin 3
DSCAM Down syndrome cell adhesion molecule
EDN1 endothelin 1
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM184A family with sequence similarity 184, member A
FAM189A2 family with sequence similarity 189, member A2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FHOD1 formin homology 2 domain containing 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GJA8 gap junction protein, alpha 8, 50kDa
GLS2 glutaminase 2 (liver, mitochondrial)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
HIST1H3I histone cluster 1, H3i
HOXB2 homeobox B2
HOXC8 homeobox C8
HSPA1L heat shock 70kDa protein 1-like
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIRREL kin of IRRE like (Drosophila)
KRT9 keratin 9, type I
LAX1 lymphocyte transmembrane adaptor 1
LEFTY1 left-right determination factor 1
LIME1 Lck interacting transmembrane adaptor 1
LPPR1 lipid phosphate phosphatase-related protein type 1
LRP3 low density lipoprotein receptor-related protein 3
MAGEA12 melanoma antigen family A12
MAPK10 mitogen-activated protein kinase 10
MBTD1 mbt domain containing 1
MEFV Mediterranean fever
MMP2 matrix metallopeptidase 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTMR12 myotubularin related protein 12
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NDNF neuron-derived neurotrophic factor
NPFFR1 neuropeptide FF receptor 1
NPPA natriuretic peptide A
NPTX1 neuronal pentraxin I
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OVGP1 oviductal glycoprotein 1, 120kDa
PARP6 poly (ADP-ribose) polymerase family, member 6
PCDH12 protocadherin 12
PCDH17 protocadherin 17
POPDC2 popeye domain containing 2
PQLC2 PQ loop repeat containing 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PROL1 proline rich, lacrimal 1
PTPRH protein tyrosine phosphatase, receptor type, H
RASL11B RAS-like, family 11, member B
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF122 ring finger protein 122
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
S1PR1 sphingosine-1-phosphate receptor 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SGK2 serum/glucocorticoid regulated kinase 2
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLITRK5 SLIT and NTRK-like family, member 5
SMO smoothened, frizzled class receptor
SSTR4 somatostatin receptor 4
STAB2 stabilin 2
SYCE1L synaptonemal complex central element protein 1-like
TAGLN3 transgelin 3
TFCP2L1 transcription factor CP2-like 1
TMEM180 transmembrane protein 180
TMEM184C transmembrane protein 184C
TRAC T cell receptor alpha constant
TSNAXIP1 translin-associated factor X interacting protein 1
USP9Y ubiquitin specific peptidase 9, Y-linked
VGF VGF nerve growth factor inducible
WFDC2 WAP four-disulfide core domain 2
WT1-AS WT1 antisense RNA
ZNF506 zinc finger protein 506
ZNF749 zinc finger protein 749
ZNF770 zinc finger protein 770