monensin-4726 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the monensin-4726 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ANGEL2 angel homolog 2 (Drosophila)
ANP32A-IT1 ANP32A intronic transcript 1
ARRB1 arrestin, beta 1
ARTN artemin
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BHLHE40 basic helix-loop-helix family, member e40
CA4 carbonic anhydrase IV
CALU calumenin
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCNG2 cyclin G2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COBLL1 cordon-bleu WH2 repeat protein-like 1
CSPP1 centrosome and spindle pole associated protein 1
CXCR4 chemokine (C-X-C motif) receptor 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DTNA dystrobrevin, alpha
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
EGR3 early growth response 3
ETV5 ets variant 5
EVA1B eva-1 homolog B (C. elegans)
FAM114A1 family with sequence similarity 114, member A1
FCF1 FCF1 rRNA-processing protein
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNS glucosamine (N-acetyl)-6-sulfatase
GOLGA2 golgin A2
GRB10 growth factor receptor-bound protein 10
GULP1 GULP, engulfment adaptor PTB domain containing 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HFE hemochromatosis
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
ICAM1 intercellular adhesion molecule 1
INHBE inhibin, beta E
INSIG1 insulin induced gene 1
IRS2 insulin receptor substrate 2
JUND jun D proto-oncogene
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KDM4B lysine (K)-specific demethylase 4B
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
LIF leukemia inhibitory factor
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MEF2D myocyte enhancer factor 2D
MVD mevalonate (diphospho) decarboxylase
NCOA2 nuclear receptor coactivator 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NUPR1 nuclear protein, transcriptional regulator, 1
ONECUT2 one cut homeobox 2
PARD6B par-6 family cell polarity regulator beta
PCDHA6 protocadherin alpha 6
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGR progesterone receptor
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLK4 polo-like kinase 4
PRKCH protein kinase C, eta
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PSPH phosphoserine phosphatase
QKI QKI, KH domain containing, RNA binding
RAB6A RAB6A, member RAS oncogene family
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPS2 ribosomal protein S2
SAP30 Sin3A-associated protein, 30kDa
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAND2P SCAN domain containing 2 pseudogene
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMIM14 small integral membrane protein 14
SOS2 son of sevenless homolog 2 (Drosophila)
SPRED2 sprouty-related, EVH1 domain containing 2
SPRY4 sprouty homolog 4 (Drosophila)
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SQLE squalene epoxidase
SRD5A3 steroid 5 alpha-reductase 3
SRPR signal recognition particle receptor (docking protein)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
VEGFA vascular endothelial growth factor A
WIPI1 WD repeat domain, phosphoinositide interacting 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YIPF5 Yip1 domain family, member 5
YTHDC2 YTH domain containing 2
YY2 YY2 transcription factor
ZNF24 zinc finger protein 24

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAM23 ADAM metallopeptidase domain 23
ADCY7 adenylate cyclase 7
AEN apoptosis enhancing nuclease
ALPK1 alpha-kinase 1
ARSB arylsulfatase B
C2ORF54 chromosome 2 open reading frame 54
CAPN5 calpain 5
CD79A CD79a molecule, immunoglobulin-associated alpha
CENPO centromere protein O
CGREF1 cell growth regulator with EF-hand domain 1
CLCN2 chloride channel, voltage-sensitive 2
CNR2 cannabinoid receptor 2 (macrophage)
CPNE7 copine VII
CRIP1 cysteine-rich protein 1 (intestinal)
CSTA cystatin A (stefin A)
CUZD1 CUB and zona pellucida-like domains 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DBF4B DBF4 zinc finger B
DOC2A double C2-like domains, alpha
DZANK1 double zinc ribbon and ankyrin repeat domains 1
FAM155A family with sequence similarity 155, member A
FAM186A family with sequence similarity 186, member A
FGF23 fibroblast growth factor 23
FLJ21369 uncharacterized protein FLJ21369
FLJ22184
FURIN furin (paired basic amino acid cleaving enzyme)
GATA4 GATA binding protein 4
GLRA1 glycine receptor, alpha 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST1H3I histone cluster 1, H3i
HOXA6 homeobox A6
HOXC8 homeobox C8
HSPB6 heat shock protein, alpha-crystallin-related, B6
ICOS inducible T-cell co-stimulator
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL2 interleukin 2
KCNK12 potassium channel, two pore domain subfamily K, member 12
KRT31 keratin 31, type I
LHX6 LIM homeobox 6
LOC730101 uncharacterized LOC730101
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPL52 mitochondrial ribosomal protein L52
MSX1 msh homeobox 1
MUM1 melanoma associated antigen (mutated) 1
NAG18 NAG18 mRNA
NEUROD1 neuronal differentiation 1
NOL10 nucleolar protein 10
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NXPH4 neurexophilin 4
OGFRL1 opioid growth factor receptor-like 1
OLFML2A olfactomedin-like 2A
PADI1 peptidyl arginine deiminase, type I
PDE12 phosphodiesterase 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLAT plasminogen activator, tissue
POLH polymerase (DNA directed), eta
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PVRL3 poliovirus receptor-related 3
RGS2 regulator of G-protein signaling 2
RNF126P1 ring finger protein 126 pseudogene 1
S100A2 S100 calcium binding protein A2
S100A9 S100 calcium binding protein A9
SAA3P serum amyloid A3 pseudogene
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERGEF secretion regulating guanine nucleotide exchange factor
SKI SKI proto-oncogene
SLC12A9 solute carrier family 12, member 9
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
TARP TCR gamma alternate reading frame protein
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TDRD12 tudor domain containing 12
TMEM184C transmembrane protein 184C
TMEM212 transmembrane protein 212
TPCN1 two pore segment channel 1
TTLL1 tubulin tyrosine ligase-like family member 1
TUBB2B tubulin, beta 2B class IIb
UPK2 uroplakin 2
VASH1 vasohibin 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF428 zinc finger protein 428
ZNF446 zinc finger protein 446
ZNF862 zinc finger protein 862