monensin-7402 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the monensin-7402 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARID1A AT rich interactive domain 1A (SWI-like)
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP7A ATPase, Cu++ transporting, alpha polypeptide
C1ORF54 chromosome 1 open reading frame 54
CA9 carbonic anhydrase IX
CARS cysteinyl-tRNA synthetase
CCNG2 cyclin G2
CCPG1 cell cycle progression 1
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDKL3 cyclin-dependent kinase-like 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNOT4 CCR4-NOT transcription complex, subunit 4
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CTSF cathepsin F
DCTN1 dynactin 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DLC1 DLC1 Rho GTPase activating protein
DND1 DND microRNA-mediated repression inhibitor 1
DOPEY2 dopey family member 2
DSCC1 DNA replication and sister chromatid cohesion 1
EFNA3 ephrin-A3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FYB FYN binding protein
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GLRB glycine receptor, beta
GMPR guanosine monophosphate reductase
GNPDA1 glucosamine-6-phosphate deaminase 1
GUSBP3 glucuronidase, beta pseudogene 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMOX1 heme oxygenase 1
IGFLR1 IGF-like family receptor 1
IGHMBP2 immunoglobulin mu binding protein 2
IL33R interleukin 33 receptor
INSIG1 insulin induced gene 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KLHL24 kelch-like family member 24
LDLR low density lipoprotein receptor
LPIN1 lipin 1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MNMIP1 manchette microtubule inner protein 1
MR1 major histocompatibility complex, class I-related
NEU1 sialidase 1 (lysosomal sialidase)
NKX3-2 NK3 homeobox 2
NOP16 NOP16 nucleolar protein
NOV nephroblastoma overexpressed
NRP2 neuropilin 2
NUPR1 nuclear protein, transcriptional regulator, 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PECAM1 platelet/endothelial cell adhesion molecule 1
PER1 period circadian clock 1
PLCD1 phospholipase C, delta 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POMT2 protein-O-mannosyltransferase 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PROSER1 proline and serine rich 1
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RPL7 ribosomal protein L7
SAPCD1 suppressor APC domain containing 1
SATB2 SATB homeobox 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SND1-IT1 SND1 intronic transcript 1
SOX4 SRY (sex determining region Y)-box 4
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SQLE squalene epoxidase
SQSTM1 sequestosome 1
SREBF2 sterol regulatory element binding transcription factor 2
STC2 stanniocalcin 2
SYNJ1 synaptojanin 1
TAOK1 TAO kinase 1
TAZ tafazzin
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TJAP1 tight junction associated protein 1 (peripheral)
TNK1 tyrosine kinase, non-receptor, 1
TRIB3 tribbles pseudokinase 3
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
WSB1 WD repeat and SOCS box containing 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF165 zinc finger protein 165
ZNF276 zinc finger protein 276
ZNF358 zinc finger protein 358
ZNF76 zinc finger protein 76
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ACKR3 atypical chemokine receptor 3
ACTG2 actin, gamma 2, smooth muscle, enteric
ADRB2 adrenoceptor beta 2, surface
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCL2A1 BCL2-related protein A1
BCL7A B-cell CLL/lymphoma 7A
C10ORF88 chromosome 10 open reading frame 88
C1QTNF1 C1q and tumor necrosis factor related protein 1
C7ORF43 chromosome 7 open reading frame 43
C9ORF114 chromosome 9 open reading frame 114
CBX8 chromobox homolog 8
CCNT1 cyclin T1
CD79A CD79a molecule, immunoglobulin-associated alpha
CDH7 cadherin 7, type 2
CHST10 carbohydrate sulfotransferase 10
CLEC10A C-type lectin domain family 10, member A
CTSK cathepsin K
CTSO cathepsin O
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL6 chemokine (C-X-C motif) ligand 6
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND3 DENN/MADD domain containing 3
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNMBP dynamin binding protein
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FGD1 FYVE, RhoGEF and PH domain containing 1
GBX2 gastrulation brain homeobox 2
GLDC glycine dehydrogenase (decarboxylating)
GRAMD1B GRAM domain containing 1B
HAS2 hyaluronan synthase 2
HIST1H2AG histone cluster 1, H2ag
HIST1H3A histone cluster 1, H3a
HIST1H3G histone cluster 1, H3g
HOXA2 homeobox A2
HOXC10 homeobox C10
HOXC13 homeobox C13
HOXC8 homeobox C8
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IL1B interleukin 1, beta
IL7R interleukin 7 receptor
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
ISYNA1 inositol-3-phosphate synthase 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA1107 KIAA1107
KRT86 keratin 86, type II
LIG4 ligase IV, DNA, ATP-dependent
LRRC61 leucine rich repeat containing 61
MANBA mannosidase, beta A, lysosomal
MB myoglobin
MEIS1 Meis homeobox 1
METTL16 methyltransferase like 16
MOB3B MOB kinase activator 3B
MTERF4 mitochondrial transcription termination factor 4
NOTCH1 notch 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUP62CL nucleoporin 62kDa C-terminal like
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PARM1 prostate androgen-regulated mucin-like protein 1
POLH polymerase (DNA directed), eta
POLL polymerase (DNA directed), lambda
PPAP2B phosphatidic acid phosphatase type 2B
PPL periplakin
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RPP25 ribonuclease P/MRP 25kDa subunit
RUNDC3B RUN domain containing 3B
SCEL sciellin
SECTM1 secreted and transmembrane 1
SH3GL2 SH3-domain GRB2-like 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SPEG SPEG complex locus
TCTN2 tectonic family member 2
TEP1 telomerase-associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM8B transmembrane protein 8B
TOB2 transducer of ERBB2, 2
UNC119 unc-119 homolog (C. elegans)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR62 WD repeat domain 62
YOD1 YOD1 deubiquitinase
ZBTB39 zinc finger and BTB domain containing 39
ZDHHC14 zinc finger, DHHC-type containing 14
ZDHHC24 zinc finger, DHHC-type containing 24
ZNF180 zinc finger protein 180
ZNF253 zinc finger protein 253
ZNF510 zinc finger protein 510
ZNF671 zinc finger protein 671
ZNF862 zinc finger protein 862