monobenzone-3054 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the monobenzone-3054 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ACAN aggrecan
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
AREG amphiregulin
ASTN1 astrotactin 1
ATF3 activating transcription factor 3
BAAT bile acid CoA:amino acid N-acyltransferase
BCL6 B-cell CLL/lymphoma 6
BIRC3 baculoviral IAP repeat containing 3
BMP7 bone morphogenetic protein 7
C14ORF105 chromosome 14 open reading frame 105
C20ORF27 chromosome 20 open reading frame 27
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMP cathelicidin antimicrobial peptide
CCL13 chemokine (C-C motif) ligand 13
CD200 CD200 molecule
CD226 CD226 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDRT1 CMT1A duplicated region transcript 1
CLCA1 chloride channel accessory 1
CLDN18 claudin 18
COL3A1 collagen, type III, alpha 1
CPB2 carboxypeptidase B2 (plasma)
CST6 cystatin E/M
CUL7 cullin 7
CXCL8 chemokine (C-X-C motif) ligand 8
DLX2 distal-less homeobox 2
EDDM3B epididymal protein 3B
EGLN3 egl-9 family hypoxia-inducible factor 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FCAR Fc fragment of IgA receptor
FGFR3 fibroblast growth factor receptor 3
GABARAPL1 GABA(A) receptor-associated protein like 1
GJA9 gap junction protein, alpha 9, 59kDa
GPM6B glycoprotein M6B
GTPBP1 GTP binding protein 1
HCAR3 hydroxycarboxylic acid receptor 3
HCRTR2 hypocretin (orexin) receptor 2
HES1 hes family bHLH transcription factor 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HYAL1 hyaluronoglucosaminidase 1
IGFBP3 insulin-like growth factor binding protein 3
IL24 interleukin 24
INSL4 insulin-like 4 (placenta)
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KLK7 kallikrein-related peptidase 7
LAMP1 lysosomal-associated membrane protein 1
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2
MAGEC3 melanoma antigen family C3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MVD mevalonate (diphospho) decarboxylase
MYRF myelin regulatory factor
NEBL nebulette
NLRP1 NLR family, pyrin domain containing 1
NTN3 netrin 3
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PHF7 PHD finger protein 7
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAC1 placenta-specific 1
PLSCR3 phospholipid scramblase 3
PMEPA1 prostate transmembrane protein, androgen induced 1
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS11 regulator of G-protein signaling 11
RIPPLY3 ripply transcriptional repressor 3
RTEL1 regulator of telomere elongation helicase 1
RUNDC3B RUN domain containing 3B
SAMD4A sterile alpha motif domain containing 4A
SCIN scinderin
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SFTPA2 surfactant protein A2
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOX15 SRY (sex determining region Y)-box 15
SPTBN5 spectrin, beta, non-erythrocytic 5
SRSF7 serine/arginine-rich splicing factor 7
ST7L suppression of tumorigenicity 7 like
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNPO2 transportin 2
TP53I11 tumor protein p53 inducible protein 11
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VSNL1 visinin-like 1
WSCD1 WSC domain containing 1
ZFHX3 zinc finger homeobox 3
ZNF276 zinc finger protein 276

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARG1 arginase 1
ARMCX4 armadillo repeat containing, X-linked 4
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
C11ORF21 chromosome 11 open reading frame 21
C7ORF43 chromosome 7 open reading frame 43
C8A complement component 8, alpha polypeptide
C8ORF44 chromosome 8 open reading frame 44
C9ORF9 chromosome 9 open reading frame 9
CCNB1 cyclin B1
CDC20 cell division cycle 20
CDKN3 cyclin-dependent kinase inhibitor 3
CEL carboxyl ester lipase
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CSAD cysteine sulfinic acid decarboxylase
DEPDC1 DEP domain containing 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
ENO2 enolase 2 (gamma, neuronal)
EXO5 exonuclease 5
FBXL7 F-box and leucine-rich repeat protein 7
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GEMIN8 gem (nuclear organelle) associated protein 8
GPR1 G protein-coupled receptor 1
GPSM2 G-protein signaling modulator 2
GRIP2 glutamate receptor interacting protein 2
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H1B histone cluster 1, H1b
HIST1H2AI histone cluster 1, H2ai
HIST1H3B histone cluster 1, H3b
HIST1H3G histone cluster 1, H3g
HIST1H4C histone cluster 1, H4c
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOXB9 homeobox B9
HOXC8 homeobox C8
IDI2-AS1 IDI2 antisense RNA 1
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA0753 KIAA0753
KIAA1107 KIAA1107
KIF20A kinesin family member 20A
KIF23 kinesin family member 23
KIFC1 kinesin family member C1
KLHL36 kelch-like family member 36
KRT20 keratin 20, type I
KRT31 keratin 31, type I
LHFP lipoma HMGIC fusion partner
LOXL3 lysyl oxidase-like 3
MBTD1 mbt domain containing 1
MED15 mediator complex subunit 15
MRPL44 mitochondrial ribosomal protein L44
MXD3 MAX dimerization protein 3
MYBPH myosin binding protein H
NCS1 neuronal calcium sensor 1
NIPAL2 NIPA-like domain containing 2
NOL10 nucleolar protein 10
OCLN occludin
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PGPEP1 pyroglutamyl-peptidase I
PLA2G1B phospholipase A2, group IB (pancreas)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLK1 polo-like kinase 1
PRICKLE3 prickle homolog 3 (Drosophila)
PSRC1 proline/serine-rich coiled-coil 1
RAB33A RAB33A, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RAP1GAP2 RAP1 GTPase activating protein 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RPGRIP1L RPGRIP1-like
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP53 ribosomal protein L23a pseudogene 53
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLITRK5 SLIT and NTRK-like family, member 5
SMR3B submaxillary gland androgen regulated protein 3B
SPATA2L spermatogenesis associated 2-like
SREK1IP1 SREK1-interacting protein 1
STRN striatin, calmodulin binding protein
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM115 transmembrane protein 115
TOP2A topoisomerase (DNA) II alpha 170kDa
TRAF2 TNF receptor-associated factor 2
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTLL1 tubulin tyrosine ligase-like family member 1
UBE2C ubiquitin-conjugating enzyme E2C
UPB1 ureidopropionase, beta
ZNF225 zinc finger protein 225
ZNF428 zinc finger protein 428
ZNF768 zinc finger protein 768