monobenzone-3391 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the monobenzone-3391 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
AGMAT agmatine ureohydrolase (agmatinase)
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANK1 ankyrin 1, erythrocytic
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGAP26 Rho GTPase activating protein 26
ARTN artemin
BDKRB2 bradykinin receptor B2
BEX1 brain expressed, X-linked 1
BMP1 bone morphogenetic protein 1
C17ORF53 chromosome 17 open reading frame 53
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CALCR calcitonin receptor
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCA3P chloride channel accessory 3, pseudogene
CPQ carboxypeptidase Q
CREBBP CREB binding protein
CT62 cancer/testis antigen 62
DAPK2 death-associated protein kinase 2
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DGCR8 DGCR8 microprocessor complex subunit
DNALI1 dynein, axonemal, light intermediate chain 1
DOK4 docking protein 4
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EGR3 early growth response 3
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FRMD1 FERM domain containing 1
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GAP43 growth associated protein 43
GCKR glucokinase (hexokinase 4) regulator
GFI1 growth factor independent 1 transcription repressor
GPER1 G protein-coupled estrogen receptor 1
GYPB glycophorin B (MNS blood group)
GZMK granzyme K (granzyme 3; tryptase II)
HFE hemochromatosis
HOXA10 homeobox A10
HR hair growth associated
INHBE inhibin, beta E
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KDM4B lysine (K)-specific demethylase 4B
KIAA1324 KIAA1324
KLHL25 kelch-like family member 25
LARP6 La ribonucleoprotein domain family, member 6
LHX2 LIM homeobox 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRP4 low density lipoprotein receptor-related protein 4
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MALL mal, T-cell differentiation protein-like
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MORN1 MORN repeat containing 1
MST1 macrophage stimulating 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MX1 MX dynamin-like GTPase 1
MXD4 MAX dimerization protein 4
MYOF myoferlin
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NOD2 nucleotide-binding oligomerization domain containing 2
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NPTX2 neuronal pentraxin II
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
NTF3 neurotrophin 3
OLFML2A olfactomedin-like 2A
OSGIN1 oxidative stress induced growth inhibitor 1
PGR progesterone receptor
RET ret proto-oncogene
RIBC2 RIB43A domain with coiled-coils 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SCAND2P SCAN domain containing 2 pseudogene
SDC3 syndecan 3
SH3GL3 SH3-domain GRB2-like 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPAG8 sperm associated antigen 8
SYNDIG1 synapse differentiation inducing 1
TACC1 transforming, acidic coiled-coil containing protein 1
TAGLN3 transgelin 3
TBXA2R thromboxane A2 receptor
TEF thyrotrophic embryonic factor
TEP1 telomerase-associated protein 1
TIMP3 TIMP metallopeptidase inhibitor 3
TMCC2 transmembrane and coiled-coil domain family 2
TMOD1 tropomodulin 1
TMPRSS2 transmembrane protease, serine 2
TPSG1 tryptase gamma 1
UGT8 UDP glycosyltransferase 8
USP22 ubiquitin specific peptidase 22
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
ZC2HC1C zinc finger, C2HC-type containing 1C
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF343 zinc finger protein 343
ZNF358 zinc finger protein 358
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACTL8 actin-like 8
ADTRP androgen-dependent TFPI-regulating protein
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATP7A ATPase, Cu++ transporting, alpha polypeptide
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C3 complement component 3
CCNB1 cyclin B1
CDC20 cell division cycle 20
CDCA3 cell division cycle associated 3
CDCA8 cell division cycle associated 8
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CEP97 centrosomal protein 97kDa
CHM choroideremia (Rab escort protein 1)
CLIP4 CAP-GLY domain containing linker protein family, member 4
CPA4 carboxypeptidase A4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DEPDC1 DEP domain containing 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EDAR ectodysplasin A receptor
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA1 ephrin-A1
ERN1 endoplasmic reticulum to nucleus signaling 1
EXD3 exonuclease 3'-5' domain containing 3
FAM64A family with sequence similarity 64, member A
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF2I general transcription factor IIi
H1F0 H1 histone family, member 0
HCAR3 hydroxycarboxylic acid receptor 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2BG histone cluster 1, H2bg
HIST1H2BJ histone cluster 1, H2bj
HIST1H4C histone cluster 1, H4c
HLA-DMA major histocompatibility complex, class II, DM alpha
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOXA4 homeobox A4
HPX hemopexin
IFT54 intraflagellar transport 54
INHA inhibin, alpha
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIF14 kinesin family member 14
KIF18A kinesin family member 18A
KIF20A kinesin family member 20A
KRT83 keratin 83, type II
LIN7A lin-7 homolog A (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LOXL3 lysyl oxidase-like 3
MDM4 MDM4, p53 regulator
METTL16 methyltransferase like 16
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRPL52 mitochondrial ribosomal protein L52
MRPS18C mitochondrial ribosomal protein S18C
MTL5 metallothionein-like 5, testis-specific (tesmin)
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDC80 NDC80 kinetochore complex component
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPM3 nucleophosmin/nucleoplasmin 3
NT5E 5'-nucleotidase, ecto (CD73)
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PARD6B par-6 family cell polarity regulator beta
PEX26 peroxisomal biogenesis factor 26
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLK1 polo-like kinase 1
PMP22 peripheral myelin protein 22
POLM polymerase (DNA directed), mu
PSRC1 proline/serine-rich coiled-coil 1
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB35 RAB35, member RAS oncogene family
RPAP2 RNA polymerase II associated protein 2
SAYSD1 SAYSVFN motif domain containing 1
SCAMP3 secretory carrier membrane protein 3
SECTM1 secreted and transmembrane 1
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLMO1 slowmo homolog 1 (Drosophila)
SPEG SPEG complex locus
SPINK5 serine peptidase inhibitor, Kazal type 5
STIM1 stromal interaction molecule 1
STK16 serine/threonine kinase 16
SUN2 Sad1 and UNC84 domain containing 2
TBKBP1 TBK1 binding protein 1
TEX40 testis expressed 40
TMEM254 transmembrane protein 254
TNS3 tensin 3
TPX2 TPX2, microtubule-associated
TROAP trophinin associated protein
WDR25 WD repeat domain 25
WLS wntless Wnt ligand secretion mediator
ZNF552 zinc finger protein 552