| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the monocrotaline-2749 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARTN | artemin |
| BAX | BCL2-associated X protein |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CAPN5 | calpain 5 |
| CCDC121 | coiled-coil domain containing 121 |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CD70 | CD70 molecule |
| CDC14B | cell division cycle 14B |
| CDK18 | cyclin-dependent kinase 18 |
| CFHR4 | complement factor H-related 4 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRMP1 | collapsin response mediator protein 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CTSF | cathepsin F |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DMTN | dematin actin binding protein |
| DOK4 | docking protein 4 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| FBLN1 | fibulin 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FH | fumarate hydratase |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GABRD | gamma-aminobutyric acid (GABA) A receptor, delta |
| GLIPR1 | GLI pathogenesis-related 1 |
| GM2A | GM2 ganglioside activator |
| GRB7 | growth factor receptor-bound protein 7 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IFT54 | intraflagellar transport 54 |
| IGLV3-19 | immunoglobulin lambda variable 3-19 |
| IL11 | interleukin 11 |
| IL1B | interleukin 1, beta |
| KDM5A | lysine (K)-specific demethylase 5A |
| KLHL28 | kelch-like family member 28 |
| LAMC2 | laminin, gamma 2 |
| MED16 | mediator complex subunit 16 |
| METTL16 | methyltransferase like 16 |
| MFN2 | mitofusin 2 |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MR1 | major histocompatibility complex, class I-related |
| MYL10 | myosin, light chain 10, regulatory |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OLFML2A | olfactomedin-like 2A |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PVR | poliovirus receptor |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB6B | RAB6B, member RAS oncogene family |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RPL35A | ribosomal protein L35a |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RTN2 | reticulon 2 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SH2D2A | SH2 domain containing 2A |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SIX2 | SIX homeobox 2 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STMN1 | stathmin 1 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| THAP9 | THAP domain containing 9 |
| THBD | thrombomodulin |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TRIM3 | tripartite motif containing 3 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TROVE2 | TROVE domain family, member 2 |
| UCN | urocortin |
| UTRN | utrophin |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| XDH | xanthine dehydrogenase |
| YIPF4 | Yip1 domain family, member 4 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTL8 | actin-like 8 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BCORL1 | BCL6 corepressor-like 1 |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CBX8 | chromobox homolog 8 |
| CCNO | cyclin O |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHKB | choline kinase beta |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CORT | cortistatin |
| CPTP | ceramide-1-phosphate transfer protein |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CXADR | coxsackie virus and adenovirus receptor |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSCAM | Down syndrome cell adhesion molecule |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FBRS | fibrosin |
| FLNB | filamin B, beta |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| H1F0 | H1 histone family, member 0 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HYI | hydroxypyruvate isomerase (putative) |
| IFT22 | intraflagellar transport 22 |
| IRF6 | interferon regulatory factor 6 |
| KDM5C | lysine (K)-specific demethylase 5C |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LAMA3 | laminin, alpha 3 |
| LHX6 | LIM homeobox 6 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MITF | microphthalmia-associated transcription factor |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MOSPD3 | motile sperm domain containing 3 |
| MXD3 | MAX dimerization protein 3 |
| NCALD | neurocalcin delta |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOL12 | nucleolar protein 12 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| ONECUT2 | one cut homeobox 2 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PROS1 | protein S (alpha) |
| PSKH1 | protein serine kinase H1 |
| RAB20 | RAB20, member RAS oncogene family |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL10L | ribosomal protein L10-like |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SMAD7 | SMAD family member 7 |
| SPAG4 | sperm associated antigen 4 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TAOK1 | TAO kinase 1 |
| TCP10 | t-complex 10 |
| TMSB15A | thymosin beta 15a |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSPAN1 | tetraspanin 1 |
| VAX2 | ventral anterior homeobox 2 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VGF | VGF nerve growth factor inducible |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF34 | zinc finger protein 34 |
| ZNF574 | zinc finger protein 574 |
| ZNF639 | zinc finger protein 639 |
| ZNF747 | zinc finger protein 747 |
