monocyte Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A mononuclear phagocytic leukocyte, 13 to 25 mm in diameter, with an ovoid or kidney-shaped nucleus, containing lacy, linear chromatin and abundant gray-blue cytoplasm filled with fine reddish and azurophilic granules. Formed in the bone marrow from promonocytes, monocytes are transported to tissues such as the lung and liver, where they develop into macrophages. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000876)
Similar Terms
Downloads & Tools

Genes

327 genes co-occuring with the biological term monocyte in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADA adenosine deaminase
ADAM17 ADAM metallopeptidase domain 17
ADAM9 ADAM metallopeptidase domain 9
ADAR adenosine deaminase, RNA-specific
ADIPOQ adiponectin, C1Q and collagen domain containing
AGER advanced glycosylation end product-specific receptor
AHR aryl hydrocarbon receptor
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
ALCAM activated leukocyte cell adhesion molecule
ALOX15 arachidonate 15-lipoxygenase
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANXA1 annexin A1
APOC3 apolipoprotein C-III
APP amyloid beta (A4) precursor protein
ASS1 argininosuccinate synthase 1
ATRN attractin
AZU1 azurocidin 1
BCL2 B-cell CLL/lymphoma 2
BMP7 bone morphogenetic protein 7
BSG basigin (Ok blood group)
BST2 bone marrow stromal cell antigen 2
C5AR1 complement component 5a receptor 1
CAMP cathelicidin antimicrobial peptide
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL1 chemokine (C-C motif) ligand 1
CCL13 chemokine (C-C motif) ligand 13
CCL15 chemokine (C-C motif) ligand 15
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL22 chemokine (C-C motif) ligand 22
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CCL8 chemokine (C-C motif) ligand 8
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD163 CD163 molecule
CD209 CD209 molecule
CD226 CD226 molecule
CD274 CD274 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD80 CD80 molecule
CD81 CD81 molecule
CD83 CD83 molecule
CD86 CD86 molecule
CD8A CD8a molecule
CD99 CD99 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHIA chitinase, acidic
CHIT1 chitinase 1 (chitotriosidase)
CLEC12A C-type lectin domain family 12, member A
CREB3 cAMP responsive element binding protein 3
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTGF connective tissue growth factor
CTSG cathepsin G
CTSL cathepsin L
CTSS cathepsin S
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR6 chemokine (C-X-C motif) receptor 6
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT4L DNA-damage-inducible transcript 4-like
DDR1 discoidin domain receptor tyrosine kinase 1
DEFB103B defensin, beta 103B
DEFB4A defensin, beta 4A
DUSP1 dual specificity phosphatase 1
DYSF dysferlin
EFNB2 ephrin-B2
EPHB2 EPH receptor B2
EPHB4 EPH receptor B4
EPHX2 epoxide hydrolase 2, cytoplasmic
F10 coagulation factor X
F11R F11 receptor
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FLT3 fms-related tyrosine kinase 3
FN1 fibronectin 1
FOXP1 forkhead box P1
GATA2 GATA binding protein 2
GBP1 guanylate binding protein 1, interferon-inducible
GHRL ghrelin/obestatin prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GLB1 galactosidase, beta 1
GPBAR1 G protein-coupled bile acid receptor 1
GPR4 G protein-coupled receptor 4
GREM1 gremlin 1, DAN family BMP antagonist
GSK3B glycogen synthase kinase 3 beta
HAMP hepcidin antimicrobial peptide
HBS1L HBS1-like translational GTPase
HDAC3 histone deacetylase 3
HFE hemochromatosis
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HOXA10 homeobox A10
HP haptoglobin
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA1A heat shock 70kDa protein 1A
HSPB1 heat shock 27kDa protein 1
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKZF2 IKAROS family zinc finger 2 (Helios)
IL10 interleukin 10
IL13 interleukin 13
IL17A interleukin 17A
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL21 interleukin 21
IL25 interleukin 25
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL6 interleukin 6
IL6R interleukin 6 receptor
IL7 interleukin 7
IRF1 interferon regulatory factor 1
IRF3 interferon regulatory factor 3
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK2 Janus kinase 2
JAM3 junctional adhesion molecule 3
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
LDLR low density lipoprotein receptor
LEP leptin
LGALS3 lectin, galactoside-binding, soluble, 3
LIF leukemia inhibitory factor
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LIPG lipase, endothelial
LPA lipoprotein, Lp(a)
LY6E lymphocyte antigen 6 complex, locus E
LYN LYN proto-oncogene, Src family tyrosine kinase
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MCAM melanoma cell adhesion molecule
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR126 microRNA 126
MIR155 microRNA 155
MIR21 microRNA 21
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP25 matrix metallopeptidase 25
MMP9 matrix metallopeptidase 9
MT1E metallothionein 1E
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1X metallothionein 1X
MYB v-myb avian myeloblastosis viral oncogene homolog
MYCBPAP MYCBP associated protein
MYD88 myeloid differentiation primary response 88
NAMPT nicotinamide phosphoribosyltransferase
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCAM1 neural cell adhesion molecule 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NGF nerve growth factor (beta polypeptide)
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX4 NADPH oxidase 4
NPPB natriuretic peptide B
NPS neuropeptide S
NPSR1 neuropeptide S receptor 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A3 nuclear receptor subfamily 4, group A, member 3
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OSCAR osteoclast associated, immunoglobulin-like receptor
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARD3 par-3 family cell polarity regulator
PARK2 parkin RBR E3 ubiquitin protein ligase
PDCD1 programmed cell death 1
PDGFC platelet derived growth factor C
PDGFD platelet derived growth factor D
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PF4 platelet factor 4
PI3 peptidase inhibitor 3, skin-derived
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLEKHO1 pleckstrin homology domain containing, family O member 1
PML promyelocytic leukemia
PMP22 peripheral myelin protein 22
PNPLA2 patatin-like phospholipase domain containing 2
PON1 paraoxonase 1
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPT1 palmitoyl-protein thioesterase 1
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKD2 protein kinase D2
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTAFR platelet-activating factor receptor
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2B protein tyrosine kinase 2 beta
PVR poliovirus receptor
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
PVRL3 poliovirus receptor-related 3
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RARA retinoic acid receptor, alpha
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RETN resistin
RPS19 ribosomal protein S19
RTN3 reticulon 3
S100A12 S100 calcium binding protein A12
SDC1 syndecan 1
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SIRPA signal-regulatory protein alpha
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLIT3 slit homolog 3 (Drosophila)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SOCS3 suppressor of cytokine signaling 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SP1 Sp1 transcription factor
SPHK1 sphingosine kinase 1
SPI1 Spi-1 proto-oncogene
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUSD6 sushi domain containing 6
SYK spleen tyrosine kinase
TAC1 tachykinin, precursor 1
TBXA2R thromboxane A2 receptor
TEK TEK tyrosine kinase, endothelial
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGM2 transglutaminase 2
THBS1 thrombospondin 1
THOC5 THO complex 5
TIMP1 TIMP metallopeptidase inhibitor 1
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRAF2 TNF receptor-associated factor 2
TRAF5 TNF receptor-associated factor 5
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPC3 transient receptor potential cation channel, subfamily C, member 3
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
VNN2 vanin 2
WISP1 WNT1 inducible signaling pathway protein 1
WNT3A wingless-type MMTV integration site family, member 3A
WNT5A wingless-type MMTV integration site family, member 5A
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZNF580 zinc finger protein 580