morphine Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A morphinane alkaloid that is a highly potent opiate analgesic psychoactive drug. Morphine acts directly on the central nervous system (CNS) to relieve pain but has a high potential for addiction, with tolerance and both physical and psychological dependence developing rapidly. Morphine is the most abundant opiate found in Papaver somniferum (the opium poppy). (Chemical Entities of Biological Interest Ontology, CHEBI_17303)
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Genes

29 genes co-occuring with the biological term morphine in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
C3 complement component 3
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
COMT catechol-O-methyltransferase
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
FLNA filamin A, alpha
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
ICAM1 intercellular adhesion molecule 1
IL10 interleukin 10
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
KLF7 Kruppel-like factor 7 (ubiquitous)
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
NPFF neuropeptide FF-amide peptide precursor
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OPRD1 opioid receptor, delta 1
OPRM1 opioid receptor, mu 1
PEBP1 phosphatidylethanolamine binding protein 1
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C
PRKCG protein kinase C, gamma
SELE selectin E
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
TLR2 toll-like receptor 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
VCAM1 vascular cell adhesion molecule 1