mortality Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Is the quantification of the number of deaths is a population. (Experimental Factor Ontology, EFO_0004352)
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Genes

361 genes co-occuring with the biological term mortality in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACTA1 actin, alpha 1, skeletal muscle
ADAM17 ADAM metallopeptidase domain 17
ADAM33 ADAM metallopeptidase domain 33
ADD1 adducin 1 (alpha)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADRA2A adrenoceptor alpha 2A
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
AFP alpha-fetoprotein
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AGTRAP angiotensin II receptor-associated protein
AHSG alpha-2-HS-glycoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALAD aminolevulinate dehydratase
ALB albumin
ALCAM activated leukocyte cell adhesion molecule
ALPL alkaline phosphatase, liver/bone/kidney
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
AOC3 amine oxidase, copper containing 3
APC adenomatous polyposis coli
APLN apelin
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APOE apolipoprotein E
AR androgen receptor
ARID1A AT rich interactive domain 1A (SWI-like)
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATM ATM serine/threonine kinase
AVP arginine vasopressin
B2M beta-2-microglobulin
B3GAT1 beta-1,3-glucuronyltransferase 1
BCHE butyrylcholinesterase
BDNF brain-derived neurotrophic factor
BGLAP bone gamma-carboxyglutamate (gla) protein
BHMT betaine--homocysteine S-methyltransferase
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
C3 complement component 3
C4B complement component 4B (Chido blood group)
C5AR1 complement component 5a receptor 1
C9ORF72 chromosome 9 open reading frame 72
CALCA calcitonin-related polypeptide alpha
CAPN10 calpain 10
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL2 chemokine (C-C motif) ligand 2
CCL21 chemokine (C-C motif) ligand 21
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD163 CD163 molecule
CD4 CD4 molecule
CD40LG CD40 ligand
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CETP cholesteryl ester transfer protein, plasma
CFH complement factor H
CGB chorionic gonadotropin, beta polypeptide
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRM2 cholinergic receptor, muscarinic 2
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CIITA class II, major histocompatibility complex, transactivator
CKM creatine kinase, muscle
CMA1 chymase 1, mast cell
CNTN2 contactin 2 (axonal)
COL18A1 collagen, type XVIII, alpha 1
COMP cartilage oligomeric matrix protein
CP ceruloplasmin (ferroxidase)
CPT1A carnitine palmitoyltransferase 1A (liver)
CRP C-reactive protein, pentraxin-related
CRY1 cryptochrome circadian clock 1
CST3 cystatin C
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSB cathepsin B
CTSS cathepsin S
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DOCK8 dedicator of cytokinesis 8
DRD2 dopamine receptor D2
EDN1 endothelin 1
ELN elastin
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESM1 endothelial cell-specific molecule 1
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
ESRRG estrogen-related receptor gamma
F2 coagulation factor II (thrombin)
F2RL3 coagulation factor II (thrombin) receptor-like 3
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FABP1 fatty acid binding protein 1, liver
FABP3 fatty acid binding protein 3, muscle and heart
FABP4 fatty acid binding protein 4, adipocyte
FAS Fas cell surface death receptor
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGF2 fibroblast growth factor 2 (basic)
FGF21 fibroblast growth factor 21
FGF23 fibroblast growth factor 23
FGG fibrinogen gamma chain
FLT1 fms-related tyrosine kinase 1
FSHR follicle stimulating hormone receptor
FST follistatin
FTO fat mass and obesity associated
GCG glucagon
GDF15 growth differentiation factor 15
GFAP glial fibrillary acidic protein
GGT1 gamma-glutamyltransferase 1
GGT2 gamma-glutamyltransferase 2
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GP6 glycoprotein VI (platelet)
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX1 glutathione peroxidase 1
GRN granulin
GSN gelsolin
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GYS1 glycogen synthase 1 (muscle)
HAMP hepcidin antimicrobial peptide
HAVCR2 hepatitis A virus cellular receptor 2
HBA1 hemoglobin, alpha 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-E major histocompatibility complex, class I, E
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
HP haptoglobin
HSPA1A heat shock 70kDa protein 1A
HSPA4 heat shock 70kDa protein 4
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IFNA2 interferon, alpha 2
IFNA8 interferon, alpha 8
IFNG interferon, gamma
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2-AS IGF2 antisense RNA
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL12B interleukin 12B
IL13 interleukin 13
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RL1 interleukin 1 receptor-like 1
IL1RN interleukin 1 receptor antagonist
IL3 interleukin 3
IL33 interleukin 33
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IL6R interleukin 6 receptor
IL7R interleukin 7 receptor
INHA inhibin, alpha
INHBA inhibin, beta A
INHBB inhibin, beta B
INHBC inhibin, beta C
INS insulin
IRAK1 interleukin-1 receptor-associated kinase 1
IRS2 insulin receptor substrate 2
JAK2 Janus kinase 2
JPH2 junctophilin 2
KAT2B K(lysine) acetyltransferase 2B
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KDM6A lysine (K)-specific demethylase 6A
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KL klotho
KLK3 kallikrein-related peptidase 3
LAMC2 laminin, gamma 2
LCN2 lipocalin 2
LEP leptin
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LMNA lamin A/C
LNPEP leucyl/cystinyl aminopeptidase
LPA lipoprotein, Lp(a)
LTA lymphotoxin alpha
LTBP2 latent transforming growth factor beta binding protein 2
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAGED4B melanoma antigen family D4B
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MGP matrix Gla protein
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR122 microRNA 122
MIR208B microRNA 208b
MIR210 microRNA 210
MIR499A microRNA 499a
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPL MPL proto-oncogene, thrombopoietin receptor
MPO myeloperoxidase
MPST mercaptopyruvate sulfurtransferase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUTYH mutY homolog
MYD88 myeloid differentiation primary response 88
NBN nibrin
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGFR nerve growth factor receptor
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NR1H3 nuclear receptor subfamily 1, group H, member 3
OPRM1 opioid receptor, mu 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PENK proenkephalin
PFN1 profilin 1
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA1A phospholipase A1 member A
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLG plasminogen
PNMT phenylethanolamine N-methyltransferase
PON1 paraoxonase 1
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PRDX4 peroxiredoxin 4
PRL prolactin
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROCR protein C receptor, endothelial
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTX3 pentraxin 3, long
RBP4 retinol binding protein 4, plasma
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RETN resistin
RFC1 replication factor C (activator 1) 1, 145kDa
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RUNX3 runt-related transcription factor 3
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SAA1 serum amyloid A1
SAA2 serum amyloid A2
SCGN secretagogin, EF-hand calcium binding protein
SCN5A sodium channel, voltage gated, type V alpha subunit
SDC1 syndecan 1
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEP15 15 kDa selenoprotein
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPB surfactant protein B
SHBG sex hormone-binding globulin
SIRT1 sirtuin 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SMAD3 SMAD family member 3
SMN1 survival of motor neuron 1, telomeric
SPTAN1 spectrin, alpha, non-erythrocytic 1
SREBF1 sterol regulatory element binding transcription factor 1
ST2 suppression of tumorigenicity 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
TFRC transferrin receptor
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
THBD thrombomodulin
THPO thrombopoietin
TICAM1 toll-like receptor adaptor molecule 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TMPRSS2 transmembrane protease, serine 2
TNF tumor necrosis factor
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNNI1 troponin I type 1 (skeletal, slow)
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TP53 tumor protein p53
TREM1 triggering receptor expressed on myeloid cells 1
TRIM37 tripartite motif containing 37
TTR transthyretin
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGT1A UDP glucuronosyltransferase 1 family, polypeptide A complex locus
UNC93B1 unc-93 homolog B1 (C. elegans)
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
WNK1 WNK lysine deficient protein kinase 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)