motile cilium Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A cilium which has a variable arrangement of axonemal microtubules, contains molecular motors, and beats with a characteristic whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface. Motile cilia are typically found in multiple copies on epithelial cells that line the lumenal ducts of various tissues. Motile cilia may also function as sensory organelles. (Gene Ontology, GO_0031514)
External Link http://amigo.geneontology.org/amigo/term/GO:0031514
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Genes

86 proteins localized to the motile cilium cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
ADCY10 adenylate cyclase 10 (soluble)
AK8 adenylate kinase 8
AKAP4 A kinase (PRKA) anchor protein 4
ANXA1 annexin A1
ARL13A ADP-ribosylation factor-like 13A
ARL13B ADP-ribosylation factor-like 13B
BBS2 Bardet-Biedl syndrome 2
BBS4 Bardet-Biedl syndrome 4
BRWD1 bromodomain and WD repeat domain containing 1
CABS1 calcium-binding protein, spermatid-specific 1
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CATSPERG catsper channel auxiliary subunit gamma
CEP20 centrosomal protein 20
CFAP100 cilia and flagella associated protein 100
CFAP161 cilia and flagella associated protein 161
CFAP20 cilia and flagella associated protein 20
CFAP206 cilia and flagella associated protein 206
CFAP221 cilia and flagella associated protein 221
CFAP251 cilia and flagella associated protein 251
CFAP300 cilia and flagella associated protein 300
CFAP45 cilia and flagella associated protein 45
CFAP52 cilia and flagella associated protein 52
CFAP61 cilia and flagella associated protein 61
CFAP70 cilia and flagella associated protein 70
CFAP73 cilia and flagella associated protein 73
CFAP91 cilia and flagella associated protein 91
DAAM1 dishevelled associated activator of morphogenesis 1
DNAAF5 dynein, axonemal, assembly factor 5
DNAH10 dynein, axonemal, heavy chain 10
DNAH11 dynein, axonemal, heavy chain 11
DNAH14 dynein, axonemal, heavy chain 14
DNAH17 dynein, axonemal, heavy chain 17
DNAH2 dynein, axonemal, heavy chain 2
DNAH3 dynein, axonemal, heavy chain 3
DNAH5 dynein, axonemal, heavy chain 5
DNAH6 dynein, axonemal, heavy chain 6
DNAH7 dynein, axonemal, heavy chain 7
DNAH9 dynein, axonemal, heavy chain 9
DNAI4 dynein axonemal intermediate chain 4
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13
DNALI1 dynein, axonemal, light intermediate chain 1
DRC7 dynein regulatory complex subunit 7
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
ENKUR enkurin, TRPC channel interacting protein
GAS8 growth arrest-specific 8
HAVCR1 hepatitis A virus cellular receptor 1
IFT27 intraflagellar transport 27
IFT46 intraflagellar transport 46
IFT52 intraflagellar transport 52
IFT74 intraflagellar transport 74
IFT81 intraflagellar transport 81
IFT88 intraflagellar transport 88
INTU inturned planar cell polarity protein
IQCG IQ motif containing G
IQUB IQ motif and ubiquitin domain containing
MKKS McKusick-Kaufman syndrome
MNS1 meiosis-specific nuclear structural 1
NME5 NME/NM23 family member 5
NPHP1 nephronophthisis 1 (juvenile)
ODAD4 outer dynein arm docking complex subunit 4
OFD1 oral-facial-digital syndrome 1
OXCT2 3-oxoacid CoA transferase 2
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PKD1 polycystic kidney disease 1 (autosomal dominant)
PRKD2 protein kinase D2
ROPN1 rhophilin associated tail protein 1
ROPN1B rhophilin associated tail protein 1B
ROPN1L rhophilin associated tail protein 1-like
RSPH1 radial spoke head 1 homolog (Chlamydomonas)
RSPH10B radial spoke head 10 homolog B (Chlamydomonas)
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas)
RSPH3 radial spoke 3 homolog (Chlamydomonas)
RSPH4A radial spoke head 4 homolog A (Chlamydomonas)
RSPH9 radial spoke head 9 homolog (Chlamydomonas)
SAXO1 stabilizer of axonemal microtubules 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SORD sorbitol dehydrogenase
SPA17 sperm autoantigenic protein 17
SPEF1 sperm flagellar 1
TAS2R43 taste receptor, type 2, member 43
TSGA10 testis specific, 10
TSSK1B testis-specific serine kinase 1B
WDR19 WD repeat domain 19
WDR54 WD repeat domain 54