moxisylyte-1804 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the moxisylyte-1804 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGFG1 ArfGAP with FG repeats 1
ANKRD12 ankyrin repeat domain 12
APP amyloid beta (A4) precursor protein
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
BCL7A B-cell CLL/lymphoma 7A
BMP2K BMP2 inducible kinase
BTN2A1 butyrophilin, subfamily 2, member A1
C18ORF25 chromosome 18 open reading frame 25
C3ORF52 chromosome 3 open reading frame 52
C9ORF156 chromosome 9 open reading frame 156
CELF1 CUGBP, Elav-like family member 1
CENPO centromere protein O
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CTSZ cathepsin Z
CUL7 cullin 7
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EGR1 early growth response 1
ELOVL2 ELOVL fatty acid elongase 2
EML2 echinoderm microtubule associated protein like 2
EXT1 exostosin glycosyltransferase 1
FBN1 fibrillin 1
FEM1B fem-1 homolog b (C. elegans)
FGF5 fibroblast growth factor 5
GDAP2 ganglioside induced differentiation associated protein 2
GLRX glutaredoxin (thioltransferase)
HAP1 huntingtin-associated protein 1
HEATR6 HEAT repeat containing 6
HEG1 heart development protein with EGF-like domains 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1D histone cluster 1, H1d
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL6 interleukin 6
IL7R interleukin 7 receptor
ING4 inhibitor of growth family, member 4
KDM6A lysine (K)-specific demethylase 6A
KIDINS220 kinase D-interacting substrate, 220kDa
KIRREL kin of IRRE like (Drosophila)
KLK10 kallikrein-related peptidase 10
KRIT1 KRIT1, ankyrin repeat containing
LDB1 LIM domain binding 1
LOC644450 uncharacterized LOC644450
LOC81691 exonuclease NEF-sp
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBP4 latent transforming growth factor beta binding protein 4
MAPK11 mitogen-activated protein kinase 11
MARC2 mitochondrial amidoxime reducing component 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MCAM melanoma cell adhesion molecule
MEX3D mex-3 RNA binding family member D
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NCKIPSD NCK interacting protein with SH3 domain
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFYA nuclear transcription factor Y, alpha
NLK nemo-like kinase
PDIA4 protein disulfide isomerase family A, member 4
PEX1 peroxisomal biogenesis factor 1
PGAP1 post-GPI attachment to proteins 1
PIDD1 p53-induced death domain protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTGES2 prostaglandin E synthase 2
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB6A RAB6A, member RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RARS arginyl-tRNA synthetase
RDX radixin
RPL23AP32 ribosomal protein L23a pseudogene 32
SFT2D2 SFT2 domain containing 2
SIRT5 sirtuin 5
SKIL SKI-like proto-oncogene
SLC38A7 solute carrier family 38, member 7
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPTAN1 spectrin, alpha, non-erythrocytic 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TK2 thymidine kinase 2, mitochondrial
TMEM121 transmembrane protein 121
TUBA4B tubulin, alpha 4b
UBOX5 U-box domain containing 5
USP48 ubiquitin specific peptidase 48
UTRN utrophin
WDR62 WD repeat domain 62
ZBTB44 zinc finger and BTB domain containing 44
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF254 zinc finger protein 254
ZNF358 zinc finger protein 358
ZNF606 zinc finger protein 606
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKRD40 ankyrin repeat domain 40
ARFRP1 ADP-ribosylation factor related protein 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARSJ arylsulfatase family, member J
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AXIN1 axin 1
BCAS3 breast carcinoma amplified sequence 3
BCCIP BRCA2 and CDKN1A interacting protein
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C6ORF47 chromosome 6 open reading frame 47
CCDC94 coiled-coil domain containing 94
CEP97 centrosomal protein 97kDa
CGREF1 cell growth regulator with EF-hand domain 1
CHKB choline kinase beta
CLCN2 chloride channel, voltage-sensitive 2
CLEC16A C-type lectin domain family 16, member A
CLK3 CDC-like kinase 3
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COQ10B coenzyme Q10 homolog B (S. cerevisiae)
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DCLRE1A DNA cross-link repair 1A
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
EPPK1 epiplakin 1
ETV4 ets variant 4
FA2H fatty acid 2-hydroxylase
FAIM Fas apoptotic inhibitory molecule
FAM53B family with sequence similarity 53, member B
FANCE Fanconi anemia, complementation group E
FBXW12 F-box and WD repeat domain containing 12
FCHO1 FCH domain only 1
FLCN folliculin
FLJ22184
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPR1 G protein-coupled receptor 1
HLX H2.0-like homeobox
HOXA1 homeobox A1
IFI6 interferon, alpha-inducible protein 6
IL33 interleukin 33
KIAA0894 KIAA0894 protein
KIFC3 kinesin family member C3
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC61 leucine rich repeat containing 61
MAGEA3 melanoma antigen family A3
MEIS1 Meis homeobox 1
MFSD11 major facilitator superfamily domain containing 11
MXRA8 matrix-remodelling associated 8
NBEAL2 neurobeachin-like 2
NME6 NME/NM23 nucleoside diphosphate kinase 6
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PECR peroxisomal trans-2-enoyl-CoA reductase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POMT1 protein-O-mannosyltransferase 1
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRICKLE3 prickle homolog 3 (Drosophila)
PTGFR prostaglandin F receptor (FP)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RANBP17 RAN binding protein 17
RPGR retinitis pigmentosa GTPase regulator
SAMHD1 SAM domain and HD domain 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SIX1 SIX homeobox 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNTA1 syntrophin, alpha 1
SPATA2L spermatogenesis associated 2-like
TEX40 testis expressed 40
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TKFC triokinase/FMN cyclase
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNNI3 troponin I type 3 (cardiac)
TSC22D4 TSC22 domain family, member 4
TSKU tsukushi, small leucine rich proteoglycan
TUBG2 tubulin, gamma 2
UBTD1 ubiquitin domain containing 1
UBTF upstream binding transcription factor, RNA polymerase I
UNC119 unc-119 homolog (C. elegans)
USP18 ubiquitin specific peptidase 18
USP6NL USP6 N-terminal like
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB22 zinc finger and BTB domain containing 22
ZC3H3 zinc finger CCCH-type containing 3
ZNF276 zinc finger protein 276
ZNF32 zinc finger protein 32