moxisylyte-7015 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the moxisylyte-7015 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACVR1B activin A receptor, type IB
ADAM19 ADAM metallopeptidase domain 19
AK1 adenylate kinase 1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AMT aminomethyltransferase
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ARL4C ADP-ribosylation factor-like 4C
ARMCX2 armadillo repeat containing, X-linked 2
ATG12 autophagy related 12
ATG13 autophagy related 13
ATN1 atrophin 1
BCL2L2 BCL2-like 2
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF61 chromosome 1 open reading frame 61
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC186 coiled-coil domain containing 186
CCL2 chemokine (C-C motif) ligand 2
CDK6 cyclin-dependent kinase 6
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CFAP69 cilia and flagella associated protein 69
COL3A1 collagen, type III, alpha 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DIO2 deiodinase, iodothyronine, type II
DMRT1 doublesex and mab-3 related transcription factor 1
DNAL4 dynein, axonemal, light chain 4
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EFNB3 ephrin-B3
FBXO11 F-box protein 11
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
FOXJ3 forkhead box J3
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GLRX3 glutaredoxin 3
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPX2 glutathione peroxidase 2
HABP4 hyaluronan binding protein 4
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXA4 homeobox A4
HOXC10 homeobox C10
HSPA12A heat shock 70kDa protein 12A
HSPB11 heat shock protein family B (small), member 11
IL17RC interleukin 17 receptor C
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KAT6A K(lysine) acetyltransferase 6A
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLK5 kallikrein-related peptidase 5
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRRC41 leucine rich repeat containing 41
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAGOH2P mago-nashi homolog 2, pseudogene
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP4 microtubule-associated protein 4
MAPK8 mitogen-activated protein kinase 8
MCM3AP minichromosome maintenance complex component 3 associated protein
MFAP3L microfibrillar-associated protein 3-like
MTERF4 mitochondrial transcription termination factor 4
NF1 neurofibromin 1
NIPAL2 NIPA-like domain containing 2
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRF1 nuclear respiratory factor 1
NRSN2 neurensin 2
ORAI2 ORAI calcium release-activated calcium modulator 2
PASK PAS domain containing serine/threonine kinase
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH12 protocadherin 12
PDE4C phosphodiesterase 4C, cAMP-specific
PDLIM5 PDZ and LIM domain 5
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PKD2L2 polycystic kidney disease 2-like 2
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PROL1 proline rich, lacrimal 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RABGAP1 RAB GTPase activating protein 1
RANGAP1 Ran GTPase activating protein 1
RASAL2 RAS protein activator like 2
RPL7 ribosomal protein L7
SCARB2 scavenger receptor class B, member 2
SENP5 SUMO1/sentrin specific peptidase 5
SH2B3 SH2B adaptor protein 3
SIK3 SIK family kinase 3
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLIT2 slit homolog 2 (Drosophila)
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SOX18 SRY (sex determining region Y)-box 18
TIMP3 TIMP metallopeptidase inhibitor 3
TMOD1 tropomodulin 1
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF136 zinc finger protein 136
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ANXA1 annexin A1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATAD5 ATPase family, AAA domain containing 5
ATP11B ATPase, class VI, type 11B
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHD1 bromo adjacent homology domain containing 1
C16ORF59 chromosome 16 open reading frame 59
CAMTA2 calmodulin binding transcription activator 2
CCDC170 coiled-coil domain containing 170
CCDC88C coiled-coil domain containing 88C
CCSER2 coiled-coil serine-rich protein 2
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CERK ceramide kinase
CIDEC cell death-inducing DFFA-like effector c
CNN2 calponin 2
CORO2A coronin, actin binding protein, 2A
COTL1 coactosin-like F-actin binding protein 1
CXORF56 chromosome X open reading frame 56
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DOCK1 dedicator of cytokinesis 1
DSCAM Down syndrome cell adhesion molecule
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EHD3 EH-domain containing 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FRS2 fibroblast growth factor receptor substrate 2
FSD1 fibronectin type III and SPRY domain containing 1
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GPHN gephyrin
GRAMD4 GRAM domain containing 4
HELZ helicase with zinc finger
HIST1H2AJ histone cluster 1, H2aj
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRAK4 interleukin-1 receptor-associated kinase 4
IRF2 interferon regulatory factor 2
KIAA0753 KIAA0753
KIF16B kinesin family member 16B
KLHL21 kelch-like family member 21
KRBOX4 KRAB box domain containing 4
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LHFPL2 lipoma HMGIC fusion partner-like 2
LIN37 lin-37 DREAM MuvB core complex component
MAMLD1 mastermind-like domain containing 1
MAP7D1 MAP7 domain containing 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MXD3 MAX dimerization protein 3
NARFL nuclear prelamin A recognition factor-like
NINL ninein-like
NME6 NME/NM23 nucleoside diphosphate kinase 6
NOTCH1 notch 1
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PIBF1 progesterone immunomodulatory binding factor 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PODXL podocalyxin-like
PRR7 proline rich 7 (synaptic)
PSKH1 protein serine kinase H1
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB17 RAB17, member RAS oncogene family
RFX7 regulatory factor X, 7
RIBC2 RIB43A domain with coiled-coils 2
RPL13P5 ribosomal protein L13 pseudogene 5
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SCAMP4 secretory carrier membrane protein 4
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT2 sirtuin 2
SLC12A8 solute carrier family 12, member 8
SLC12A9 solute carrier family 12, member 9
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
TBC1D12 TBC1 domain family, member 12
TBC1D31 TBC1 domain family, member 31
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TGFB3 transforming growth factor, beta 3
TMEM2 transmembrane protein 2
UBE2O ubiquitin-conjugating enzyme E2O
USP21 ubiquitin specific peptidase 21
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR13 WD repeat domain 13
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZDHHC18 zinc finger, DHHC-type containing 18
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF14 zinc finger protein 14
ZNF189 zinc finger protein 189
ZNF276 zinc finger protein 276
ZNF668 zinc finger protein 668
ZNF8 zinc finger protein 8