| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the moxonidine-2923 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| AIM1L | absent in melanoma 1-like |
| AMACR | alpha-methylacyl-CoA racemase |
| ANK2 | ankyrin 2, neuronal |
| AQP1 | aquaporin 1 (Colton blood group) |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| B9D1 | B9 protein domain 1 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CAT | catalase |
| CAV2 | caveolin 2 |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CD1A | CD1a molecule |
| CD59 | CD59 molecule, complement regulatory protein |
| CDC14A | cell division cycle 14A |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CFAP45 | cilia and flagella associated protein 45 |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLEC4A | C-type lectin domain family 4, member A |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CRYAA | crystallin, alpha A |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DAPK3 | death-associated protein kinase 3 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EPHA5 | EPH receptor A5 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FDXR | ferredoxin reductase |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FOXO1 | forkhead box O1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GPC3 | glypican 3 |
| GSG1 | germ cell associated 1 |
| GTPBP4 | GTP binding protein 4 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| IL1R2 | interleukin 1 receptor, type II |
| IRS4 | insulin receptor substrate 4 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JAG2 | jagged 2 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KHSRP | KH-type splicing regulatory protein |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| KSR1 | kinase suppressor of ras 1 |
| LATS1 | large tumor suppressor kinase 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRRC6 | leucine rich repeat containing 6 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAOA | monoamine oxidase A |
| MAPK11 | mitogen-activated protein kinase 11 |
| MLN | motilin |
| MPDZ | multiple PDZ domain protein |
| MPZ | myelin protein zero |
| MUC3B | mucin 3B, cell surface associated |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NLE1 | notchless homolog 1 (Drosophila) |
| PCGF2 | polycomb group ring finger 2 |
| POU5F1B | POU class 5 homeobox 1B |
| POU6F1 | POU class 6 homeobox 1 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RETN | resistin |
| RHBDD3 | rhomboid domain containing 3 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RUNX1 | runt-related transcription factor 1 |
| SELPLG | selectin P ligand |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 |
| SMC1A | structural maintenance of chromosomes 1A |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SSTR5 | somatostatin receptor 5 |
| STAC | SH3 and cysteine rich domain |
| STX2 | syntaxin 2 |
| SYT2 | synaptotagmin II |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAT | tyrosine aminotransferase |
| TGFB1 | transforming growth factor, beta 1 |
| TMEM2 | transmembrane protein 2 |
| TPMT | thiopurine S-methyltransferase |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAF4 | TNF receptor-associated factor 4 |
| TRD | T cell receptor delta locus |
| TSC2 | tuberous sclerosis 2 |
| WDR4 | WD repeat domain 4 |
| WWOX | WW domain containing oxidoreductase |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZNF137P | zinc finger protein 137, pseudogene |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AMT | aminomethyltransferase |
| ARL15 | ADP-ribosylation factor-like 15 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C5 | complement component 5 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CD180 | CD180 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CIC | capicua transcriptional repressor |
| CIDEB | cell death-inducing DFFA-like effector b |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CPTP | ceramide-1-phosphate transfer protein |
| CSF1R | colony stimulating factor 1 receptor |
| CTSD | cathepsin D |
| CTSL | cathepsin L |
| DENND2D | DENN/MADD domain containing 2D |
| DNMBP | dynamin binding protein |
| EGR2 | early growth response 2 |
| FAM53B | family with sequence similarity 53, member B |
| FANCF | Fanconi anemia, complementation group F |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FGF9 | fibroblast growth factor 9 |
| GIN1 | gypsy retrotransposon integrase 1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GK3P | glycerol kinase 3 pseudogene |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPR85 | G protein-coupled receptor 85 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H2BN | histone cluster 1, H2bn |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KIF24 | kinesin family member 24 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LIMD2 | LIM domain containing 2 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MBTD1 | mbt domain containing 1 |
| METTL2B | methyltransferase like 2B |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MYO5C | myosin VC |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PADI2 | peptidyl arginine deiminase, type II |
| PARPBP | PARP1 binding protein |
| PDZD7 | PDZ domain containing 7 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIR | pirin (iron-binding nuclear protein) |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PLA2G15 | phospholipase A2, group XV |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| SCAI | suppressor of cancer cell invasion |
| SEC31B | SEC31 homolog B (S. cerevisiae) |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SLAMF7 | SLAM family member 7 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC38A10 | solute carrier family 38, member 10 |
| SPAG4 | sperm associated antigen 4 |
| STON1 | stonin 1 |
| SUOX | sulfite oxidase |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TCTA | T-cell leukemia translocation altered |
| TEP1 | telomerase-associated protein 1 |
| THAP10 | THAP domain containing 10 |
| THBS3 | thrombospondin 3 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TPCN1 | two pore segment channel 1 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSPAN13 | tetraspanin 13 |
| UCN | urocortin |
| VNN1 | vanin 1 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF493 | zinc finger protein 493 |
| ZNF574 | zinc finger protein 574 |
