| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the moxonidine-4084 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| APOC4 | apolipoprotein C-IV |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARTN | artemin |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BBC3 | BCL2 binding component 3 |
| BMP4 | bone morphogenetic protein 4 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C2CD2L | C2CD2-like |
| CASR | calcium-sensing receptor |
| CCDC170 | coiled-coil domain containing 170 |
| CD6 | CD6 molecule |
| CEP152 | centrosomal protein 152kDa |
| CLEC4M | C-type lectin domain family 4, member M |
| CLTA | clathrin, light chain A |
| CLTC | clathrin, heavy chain (Hc) |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDN | dendrin |
| DST | dystonin |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) |
| FGF22 | fibroblast growth factor 22 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FRMD4A | FERM domain containing 4A |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GABRG3 | gamma-aminobutyric acid (GABA) A receptor, gamma 3 |
| GALR3 | galanin receptor 3 |
| GNRHR | gonadotropin-releasing hormone receptor |
| GPR161 | G protein-coupled receptor 161 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GTF2I | general transcription factor IIi |
| HOXD10 | homeobox D10 |
| IGHM | immunoglobulin heavy constant mu |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IL1RN | interleukin 1 receptor antagonist |
| IL32 | interleukin 32 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IQCC | IQ motif containing C |
| IRF4 | interferon regulatory factor 4 |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| JAG1 | jagged 1 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KIF1C | kinesin family member 1C |
| KLF12 | Kruppel-like factor 12 |
| KLK10 | kallikrein-related peptidase 10 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LAMA2 | laminin, alpha 2 |
| LIPG | lipase, endothelial |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| METTL7A | methyltransferase like 7A |
| MLANA | melan-A |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NEK9 | NIMA-related kinase 9 |
| NF1 | neurofibromin 1 |
| OPRK1 | opioid receptor, kappa 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PGK2 | phosphoglycerate kinase 2 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLCH2 | phospholipase C, eta 2 |
| PLN | phospholamban |
| PLXDC1 | plexin domain containing 1 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBM12B-AS1 | RBM12B antisense RNA 1 |
| RDH8 | retinol dehydrogenase 8 (all-trans) |
| RGS6 | regulator of G-protein signaling 6 |
| RIF1 | replication timing regulatory factor 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPLP2 | ribosomal protein, large, P2 |
| RRAD | Ras-related associated with diabetes |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC13A4 | solute carrier family 13 (sodium/sulfate symporter), member 4 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| SUGP1 | SURP and G patch domain containing 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TGFB2 | transforming growth factor, beta 2 |
| TNIK | TRAF2 and NCK interacting kinase |
| TNNT3 | troponin T type 3 (skeletal, fast) |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| USP22 | ubiquitin specific peptidase 22 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| XCL1 | chemokine (C motif) ligand 1 |
| ZNF391 | zinc finger protein 391 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ACE | angiotensin I converting enzyme |
| ADAMTS20 | ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APH1B | APH1B gamma secretase subunit |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARL15 | ADP-ribosylation factor-like 15 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAGE | B melanoma antigen |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BTC | betacellulin |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CD82 | CD82 molecule |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) |
| CDIP1 | cell death-inducing p53 target 1 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNTFR | ciliary neurotrophic factor receptor |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CXORF21 | chromosome X open reading frame 21 |
| DENND4A | DENN/MADD domain containing 4A |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DPYS | dihydropyrimidinase |
| DUSP8 | dual specificity phosphatase 8 |
| EFNB1 | ephrin-B1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FBXO31 | F-box protein 31 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GAN | gigaxonin |
| GAS8 | growth arrest-specific 8 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPR1 | G protein-coupled receptor 1 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HIST1H3F | histone cluster 1, H3f |
| HOXA4 | homeobox A4 |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IFT140 | intraflagellar transport 140 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KLC2 | kinesin light chain 2 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KLF3 | Kruppel-like factor 3 (basic) |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOC157562 | uncharacterized LOC157562 |
| LUM | lumican |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MMP9 | matrix metallopeptidase 9 |
| MTA2 | metastasis associated 1 family, member 2 |
| MYLK | myosin light chain kinase |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NGF | nerve growth factor (beta polypeptide) |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PPL | periplakin |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRR7 | proline rich 7 (synaptic) |
| RAB40A | RAB40A, member RAS oncogene family |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RFPL3 | ret finger protein-like 3 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SETD1A | SET domain containing 1A |
| SIRT6 | sirtuin 6 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SSTR4 | somatostatin receptor 4 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBKBP1 | TBK1 binding protein 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| THRB | thyroid hormone receptor, beta |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF253 | zinc finger protein 253 |
| ZNF268 | zinc finger protein 268 |
| ZNF428 | zinc finger protein 428 |
| ZNF549 | zinc finger protein 549 |
| ZNF747 | zinc finger protein 747 |
| ZNF768 | zinc finger protein 768 |