| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the moxonidine-7343 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADORA1 | adenosine A1 receptor |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALS2CL | ALS2 C-terminal like |
| AR | androgen receptor |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARRB1 | arrestin, beta 1 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATXN2L | ataxin 2-like |
| BIN1 | bridging integrator 1 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCDC57 | coiled-coil domain containing 57 |
| CDC25C | cell division cycle 25C |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CES3 | carboxylesterase 3 |
| CHKB | choline kinase beta |
| CHST10 | carbohydrate sulfotransferase 10 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COL11A2 | collagen, type XI, alpha 2 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CRY2 | cryptochrome circadian clock 2 |
| CTAGE5 | CTAGE family, member 5 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DSCAM | Down syndrome cell adhesion molecule |
| DTNA | dystrobrevin, alpha |
| EFNA3 | ephrin-A3 |
| EPHA1 | EPH receptor A1 |
| EPN1 | epsin 1 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM184A | family with sequence similarity 184, member A |
| FAM65A | family with sequence similarity 65, member A |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FRK | fyn-related Src family tyrosine kinase |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| HSF1 | heat shock transcription factor 1 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IDS | iduronate 2-sulfatase |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IL11 | interleukin 11 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MIIP | migration and invasion inhibitory protein |
| MNDA | myeloid cell nuclear differentiation antigen |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NEUROD4 | neuronal differentiation 4 |
| NF1 | neurofibromin 1 |
| NME5 | NME/NM23 family member 5 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PRKCA | protein kinase C, alpha |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAB40C | RAB40C, member RAS oncogene family |
| RASAL2 | RAS protein activator like 2 |
| RASL11B | RAS-like, family 11, member B |
| RGS12 | regulator of G-protein signaling 12 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RPL7 | ribosomal protein L7 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SCRN3 | secernin 3 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SFTPB | surfactant protein B |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SNX13 | sorting nexin 13 |
| SSPN | sarcospan |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| SYMPK | symplekin |
| TBC1D30 | TBC1 domain family, member 30 |
| TGFB2 | transforming growth factor, beta 2 |
| TMEM63A | transmembrane protein 63A |
| UBOX5 | U-box domain containing 5 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| VPS9D1 | VPS9 domain containing 1 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATF3 | activating transcription factor 3 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAGE | B melanoma antigen |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CAPN5 | calpain 5 |
| CARD8 | caspase recruitment domain family, member 8 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC85C | coiled-coil domain containing 85C |
| CCNT1 | cyclin T1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| COQ6 | coenzyme Q6 monooxygenase |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNAL4 | dynein, axonemal, light chain 4 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| ESRP2 | epithelial splicing regulatory protein 2 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPC3 | glypican 3 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4F | histone cluster 1, H4f |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HYI | hydroxypyruvate isomerase (putative) |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KAT2B | K(lysine) acetyltransferase 2B |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC642236 | FSHD region gene 1 pseudogene |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MCOLN3 | mucolipin 3 |
| MMD | monocyte to macrophage differentiation-associated |
| MXD3 | MAX dimerization protein 3 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEK11 | NIMA-related kinase 11 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NRSN2 | neurensin 2 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| ONECUT2 | one cut homeobox 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OTUD3 | OTU deubiquitinase 3 |
| PCDHB3 | protocadherin beta 3 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| RANBP17 | RAN binding protein 17 |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF170 | ring finger protein 170 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SDC3 | syndecan 3 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SREK1IP1 | SREK1-interacting protein 1 |
| SUSD6 | sushi domain containing 6 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| THOP1 | thimet oligopeptidase 1 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMC7 | transmembrane channel-like 7 |
| TMEM121 | transmembrane protein 121 |
| TMEM180 | transmembrane protein 180 |
| TMEM209 | transmembrane protein 209 |
| TRAIP | TRAF interacting protein |
| TRIM25 | tripartite motif containing 25 |
| TSPAN5 | tetraspanin 5 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| USB1 | U6 snRNA biogenesis 1 |
| VASH2 | vasohibin 2 |
| VAX2 | ventral anterior homeobox 2 |
| WDR62 | WD repeat domain 62 |
| WDR76 | WD repeat domain 76 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF14 | zinc finger protein 14 |
| ZNF248 | zinc finger protein 248 |
| ZNF254 | zinc finger protein 254 |
| ZNF273 | zinc finger protein 273 |
| ZNF571 | zinc finger protein 571 |
| ZNF816 | zinc finger protein 816 |
