mpo Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description myeloperoxidase|Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014] (NCBI Entrez Gene Database, 4353)
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Genes

37 genes co-occuring with the biological term mpo in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
APOA1 apolipoprotein A-I
CAT catalase
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CP ceruloplasmin (ferroxidase)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPX eosinophil peroxidase
ERCC2 excision repair cross-complementation group 2
ERP29 endoplasmic reticulum protein 29
FABP3 fatty acid binding protein 3, muscle and heart
GSTP1 glutathione S-transferase pi 1
HP haptoglobin
IL17A interleukin 17A
IL6 interleukin 6
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
LPO lactoperoxidase
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NQO1 NAD(P)H dehydrogenase, quinone 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAU plasminogen activator, urokinase
PON1 paraoxonase 1
PRDX6 peroxiredoxin 6
PRTN3 proteinase 3
PXDN peroxidasin
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XDH xanthine dehydrogenase
XPA xeroderma pigmentosum, complementation group A
ZNF296 zinc finger protein 296