mre11 complex Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins. (Gene Ontology, GO_0030870)
External Link http://amigo.geneontology.org/amigo/term/GO:0030870
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Genes

6 proteins localized to the mre11 complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
NBN nibrin
RAD50 RAD50 homolog (S. cerevisiae)
SP100 SP100 nuclear antigen
TERF2 telomeric repeat binding factor 2
TERF2IP telomeric repeat binding factor 2, interacting protein