mrna cleavage and polyadenylation specificity factor complex Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal. (Gene Ontology, GO_0005847)
External Link http://amigo.geneontology.org/amigo/term/GO:0005847
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10 proteins localized to the mrna cleavage and polyadenylation specificity factor complex cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CSNK1A1 casein kinase 1, alpha 1
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
FIP1L1 factor interacting with PAPOLA and CPSF1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WDR33 WD repeat domain 33
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