msh2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description mutS homolog 2|This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] (NCBI Entrez Gene Database, 4436)
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Genes

45 genes co-occuring with the biological term msh2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADCY2 adenylate cyclase 2 (brain)
AKT1 v-akt murine thymoma viral oncogene homolog 1
APC adenomatous polyposis coli
ATR ATR serine/threonine kinase
BCL2 B-cell CLL/lymphoma 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CXCR4 chemokine (C-X-C motif) receptor 4
DMPK dystrophia myotonica-protein kinase
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EPCAM epithelial cell adhesion molecule
ERCC2 excision repair cross-complementation group 2
FHIT fragile histidine triad
GRHL2 grainyhead-like 2 (Drosophila)
HDAC6 histone deacetylase 6
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPK heterogeneous nuclear ribonucleoprotein K
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KRAS Kirsten rat sarcoma viral oncogene homolog
MGMT O-6-methylguanine-DNA methyltransferase
MHS2 malignant hyperthermia susceptibility 2
MIR21 microRNA 21
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MSH6 mutS homolog 6
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
PARP1 poly (ADP-ribose) polymerase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PINK1 PTEN induced putative kinase 1
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLH polymerase (DNA directed), eta
PRKCZ protein kinase C, zeta
PTEN phosphatase and tensin homolog
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAD51 RAD51 recombinase
SPARCL1 SPARC-like 1 (hevin)
TERT telomerase reverse transcriptase
TP53 tumor protein p53
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1