msh homeobox 2|This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4488)
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24 genes co-occuring with the biological term msx2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
