metal-regulatory transcription factor 1|This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4520)
Similar Terms
Downloads & Tools
Genes
7 genes co-occuring with the biological term mtf1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
