muc2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description mucin 2, oligomeric mucus/gel-forming|This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4583)
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Genes

42 genes co-occuring with the biological term muc2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
APC adenomatous polyposis coli
ATF1 activating transcription factor 1
ATOH1 atonal homolog 1 (Drosophila)
CAMP cathelicidin antimicrobial peptide
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDX2 caudal type homeobox 2
CREB1 cAMP responsive element binding protein 1
EGFR epidermal growth factor receptor
FGF2 fibroblast growth factor 2 (basic)
IL1B interleukin 1, beta
IL6 interleukin 6
JUN jun proto-oncogene
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT20 keratin 20, type I
LGALS3 lectin, galactoside-binding, soluble, 3
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MME membrane metallo-endopeptidase
MUC1 mucin 1, cell surface associated
MUC17 mucin 17, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC3 intestinal mucin-like
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MUC8 mucin 8
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTEN phosphatase and tensin homolog
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SMAD4 SMAD family member 4
SOX9 SRY (sex determining region Y)-box 9
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TP53 tumor protein p53