multifactorial inheritance Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A mode of inheritance that depends on a mixture of major and minor genetic determinants possibly together with environmental factors. Diseases inherited in this manner are termed complex diseases. (Human Phenotype Ontology, HP_0001426)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0001426
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Genes

28 genes associated with the multifactorial inheritance phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
AGTR1 angiotensin II receptor, type 1
APOL1 apolipoprotein L, 1
BAX BCL2-associated X protein
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
CST3 cystatin C
FLT3 fms-related tyrosine kinase 3
GDF3 growth differentiation factor 3
GDF6 growth differentiation factor 6
GJB2 gap junction protein, beta 2, 26kDa
GJB3 gap junction protein, beta 3, 31kDa
GJB6 gap junction protein, beta 6, 30kDa
IRF6 interferon regulatory factor 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
NBN nibrin
NLGN4X neuroligin 4, X-linked
NLRP1 NLR family, pyrin domain containing 1
PAX4 paired box 4
PNMT phenylethanolamine N-methyltransferase
PPARG peroxisome proliferator-activated receptor gamma
PTGIS prostaglandin I2 (prostacyclin) synthase
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SHANK3 SH3 and multiple ankyrin repeat domains 3
SLITRK1 SLIT and NTRK-like family, member 1
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
STOX1 storkhead box 1
TP53 tumor protein p53