myc_00000000_e13dot5_heart_lof_mouse_gpl4865_gse7162 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE7162
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Genes

136 genes differentially expressed following the myc_00000000_e13dot5_heart_lof_mouse_gpl4865_gse7162 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
KANSL1L KAT8 regulatory NSL complex subunit 1-like 0.224482
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 0.217369
TATDN3 TatD DNase domain containing 3 0.207652
RNPC3 RNA-binding region (RNP1, RRM) containing 3 0.207397
TSSK2 testis-specific serine kinase 2 0.204931
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 0.199807
PRSS23 protease, serine, 23 0.193404
BCL2 B-cell CLL/lymphoma 2 0.193271
TMEM128 transmembrane protein 128 0.188984
STK16 serine/threonine kinase 16 0.188109
LGALS4 lectin, galactoside-binding, soluble, 4 0.182031
OCSTAMP osteoclast stimulatory transmembrane protein 0.169725
TARDBP TAR DNA binding protein 0.162454
IRF9 interferon regulatory factor 9 0.159754
FAIM Fas apoptotic inhibitory molecule 0.156314
MTCP1 mature T-cell proliferation 1 0.154162
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 0.145304
TRIM68 tripartite motif containing 68 0.144815
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa 0.139867
TTC23 tetratricopeptide repeat domain 23 0.139458
C3ORF18 chromosome 3 open reading frame 18 0.138781
RB1CC1 RB1-inducible coiled-coil 1 0.13807
EPHA10 EPH receptor A10 0.130965
OLFM1 olfactomedin 1 0.122985
INS insulin 0.114958
ILF2 interleukin enhancer binding factor 2 0.103634
CLASP1 cytoplasmic linker associated protein 1 0.093286
CAT catalase 0.091963
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 0.091636
TPH1 tryptophan hydroxylase 1 0.087531
TUBA8 tubulin, alpha 8 0.073588
GPBP1L1 GC-rich promoter binding protein 1-like 1 0.069581
MCPH1 microcephalin 1 0.067944
ZNF521 zinc finger protein 521 0.058072
PRR15 proline rich 15 0.057194
PRPF38A pre-mRNA processing factor 38A 0.056681
DKK4 dickkopf WNT signaling pathway inhibitor 4 0.048087
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 0.047707
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 0.047444
PARK2 parkin RBR E3 ubiquitin protein ligase 0.037353
YME1L1 YME1-like 1 ATPase 0.032865
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.030722
TMEM218 transmembrane protein 218 0.023871
ZNF202 zinc finger protein 202 0.022944
C1ORF43 chromosome 1 open reading frame 43 0.019687
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.019687
C12ORF60 chromosome 12 open reading frame 60 0.018359
GSTM5 glutathione S-transferase mu 5 0.003723
STC1 stanniocalcin 1 0.003411
PMVK phosphomevalonate kinase 7.65E-4

decreased expression

Symbol Name Standardized Value
ERCC4 excision repair cross-complementation group 4 -1.32055
ZNF704 zinc finger protein 704 -1.29188
EIF3G eukaryotic translation initiation factor 3, subunit G -1.27042
SVOPL SVOP-like -1.24685
RNMTL1 RNA methyltransferase like 1 -1.23489
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) -1.16553
ACOT7 acyl-CoA thioesterase 7 -1.15075
PNKP polynucleotide kinase 3'-phosphatase -1.14621
LIN7B lin-7 homolog B (C. elegans) -1.10503
DTNA dystrobrevin, alpha -1.0846
DHCR24 24-dehydrocholesterol reductase -1.08237
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 -1.08014
TLX2 T-cell leukemia homeobox 2 -1.01956
RAB5A RAB5A, member RAS oncogene family -1.00988
ADAM1B ADAM metallopeptidase domain 1B (pseudogene) -1.00085
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase -0.991529
SCT secretin -0.973849
LMNA lamin A/C -0.955932
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.949204
ASB17 ankyrin repeat and SOCS box containing 17 -0.894436
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein -0.868595
HTRA2 HtrA serine peptidase 2 -0.811096
KRTAP1-5 keratin associated protein 1-5 -0.801946
C1QBP complement component 1, q subcomponent binding protein -0.791172
EXOC3L1 exocyst complex component 3-like 1 -0.780767
OR4C6 olfactory receptor, family 4, subfamily C, member 6 -0.762776
SORCS1 sortilin-related VPS10 domain containing receptor 1 -0.747805
EXTL3 exostosin-like glycosyltransferase 3 -0.704294
PSAPL1 prosaposin-like 1 (gene/pseudogene) -0.658228
LYNX1 Ly6/neurotoxin 1 -0.652728
PLD3 phospholipase D family, member 3 -0.650861
CSNK1D casein kinase 1, delta -0.618335
IL1F10 interleukin 1 family, member 10 (theta) -0.617329
OR8J3 olfactory receptor, family 8, subfamily J, member 3 -0.614186
DCAF4 DDB1 and CUL4 associated factor 4 -0.601728
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 -0.590931
DPF3 D4, zinc and double PHD fingers, family 3 -0.586836
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 -0.583811
TGIF2 TGFB-induced factor homeobox 2 -0.58285
ZBTB6 zinc finger and BTB domain containing 6 -0.571818
C1QTNF6 C1q and tumor necrosis factor related protein 6 -0.567821
HLA-A major histocompatibility complex, class I, A -0.565731
CD4 CD4 molecule -0.556343
NRTN neurturin -0.55066
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 -0.550555
ZNF628 zinc finger protein 628 -0.544384
ZBTB37 zinc finger and BTB domain containing 37 -0.542276
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 -0.535814
NHLH2 nescient helix loop helix 2 -0.531042
USP38 ubiquitin specific peptidase 38 -0.518092
LIX1 Lix1 homolog (chicken) -0.503106
TPGS1 tubulin polyglutamylase complex subunit 1 -0.495147
TNRC18 trinucleotide repeat containing 18 -0.494102
PMM1 phosphomannomutase 1 -0.479614
TBC1D20 TBC1 domain family, member 20 -0.472852
TMEM220 transmembrane protein 220 -0.472087
GTF3A general transcription factor IIIA -0.467785
GSDMA gasdermin A -0.46605
PPAP2A phosphatidic acid phosphatase type 2A -0.462496
PLEC plectin -0.454476
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.449379
PNKD paroxysmal nonkinesigenic dyskinesia -0.442354
FAM69B family with sequence similarity 69, member B -0.44051
HR hair growth associated -0.440206
TMEM104 transmembrane protein 104 -0.436333
TEX2 testis expressed 2 -0.0562
TMEM230 transmembrane protein 230 -0.055506
LARP4B La ribonucleoprotein domain family, member 4B -0.055154
FAM45A family with sequence similarity 45, member A -0.055095
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -0.052841
RPL31 ribosomal protein L31 -0.048192
SFR1 SWI5-dependent recombination repair 1 -0.041085
SH3GLB1 SH3-domain GRB2-like endophilin B1 -0.03719
SEC24A SEC24 family member A -0.036458
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.036157
C2ORF50 chromosome 2 open reading frame 50 -0.03473
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.033838
MDM1 Mdm1 nuclear protein homolog (mouse) -0.031368
KPNA3 karyopherin alpha 3 (importin alpha 4) -0.024097
SON SON DNA binding protein -0.018981
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 -0.017565
IQCA1 IQ motif containing with AAA domain 1 -0.015388
ERI1 exoribonuclease 1 -0.007305
EPHA3 EPH receptor A3 -0.007024
LMOD2 leiomodin 2 (cardiac) -0.005953
CPOX coproporphyrinogen oxidase -0.003025
Funding