mycn Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog|This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] (NCBI Entrez Gene Database, 4613)
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Genes

83 genes co-occuring with the biological term mycn in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALK anaplastic lymphoma receptor tyrosine kinase
ARID3B AT rich interactive domain 3B (BRIGHT-like)
AURKA aurora kinase A
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BIN1 bridging integrator 1
BIRC5 baculoviral IAP repeat containing 5
BIRC7 baculoviral IAP repeat containing 7
BMI1 BMI1 proto-oncogene, polycomb ring finger
CADM1 cell adhesion molecule 1
CCND2 cyclin D2
CCND3 cyclin D3
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKL5 cyclin-dependent kinase-like 5
CDKN2A cyclin-dependent kinase inhibitor 2A
CRABP2 cellular retinoic acid binding protein 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL3 dihydropyrimidinase-like 3
E2F1 E2F transcription factor 1
EIF5A eukaryotic translation initiation factor 5A
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
ESR1 estrogen receptor 1
GCLC glutamate-cysteine ligase, catalytic subunit
GLI1 GLI family zinc finger 1
GSK3B glycogen synthase kinase 3 beta
HDAC1 histone deacetylase 1
HIPK2 homeodomain interacting protein kinase 2
HLA-A major histocompatibility complex, class I, A
HMGA1 high mobility group AT-hook 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ITGA1 integrin, alpha 1
KIF1B kinesin family member 1B
LIN28B lin-28 homolog B (C. elegans)
LRRN3 leucine rich repeat neuronal 3
MAX MYC associated factor X
MCL1 myeloid cell leukemia 1
MCM7 minichromosome maintenance complex component 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MIR101-1 microRNA 101-1
MIR145 microRNA 145
MIR184 microRNA 184
MIR202 microRNA 202
MIR21 microRNA 21
MIR210 microRNA 210
MIR335 microRNA 335
MIR34A microRNA 34a
MIR9-1 microRNA 9-1
MIRLET7A1 microRNA let-7a-1
MNT MAX network transcriptional repressor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYCNOS MYCN opposite strand
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGFR nerve growth factor receptor
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
ODC1 ornithine decarboxylase 1
PAX3 paired box 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PROM1 prominin 1
PTPRD protein tyrosine phosphatase, receptor type, D
RB1 retinoblastoma 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RUNX3 runt-related transcription factor 3
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SULF2 sulfatase 2
TFPI2 tissue factor pathway inhibitor 2
TGFBI transforming growth factor, beta-induced, 68kDa
TP53 tumor protein p53
TRIM32 tripartite motif containing 32
ZBTB17 zinc finger and BTB domain containing 17