myelin sheath Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The cylindrical covering on the axons of some neurons; it consists of concentric layers of myelin, formed in the peripheral nervous system by the plasma membrane of Schwann cells, and in the central nervous system by oligodendrocytes. It is interrupted at intervals along its length by gaps known as nodes of Ranvier. Myelin is an electrical insulator that serves to speed the conduction of nerve impulses. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000900)
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38 proteins localized to the myelin sheath cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 0.663342
MBP myelin basic protein 0.663342
NCMAP noncompact myelin associated protein 0.237908
SIRT2 sirtuin 2 0.237908
FAM213B family with sequence similarity 213, member B 0.098109
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.098109
CNTN2 contactin 2 (axonal) 0.098109
PTEN phosphatase and tensin homolog 0.098109
CA2 carbonic anhydrase II 0.03318
STX4 syntaxin 4 0.03318
CA13 carbonic anhydrase XIII 0.03318
PLP1 proteolipid protein 1 0.03318
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.03318
HRH3 histamine receptor H3 0.03318
CLDN5 claudin 5 0.03318
MAG myelin associated glycoprotein 0.03318
PRKCI protein kinase C, iota 0.03318
PRKCZ protein kinase C, zeta 0.03318
MPDZ multiple PDZ domain protein 0.03318
TSPAN2 tetraspanin 2 0.03318
GJC2 gap junction protein, gamma 2, 47kDa 0.03318
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 0.03318
GJC3 gap junction protein, gamma 3, 30.2kDa 0.03318
BCL2 B-cell CLL/lymphoma 2 0.03318
SCRIB scribbled planar cell polarity protein 0.03318
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.03318
PLLP plasmolipin 0.03318
CD59 CD59 molecule, complement regulatory protein 0.03318
SERINC5 serine incorporator 5 0.03318
LLGL1 lethal giant larvae homolog 1 (Drosophila) 0.03318
ERMN ermin, ERM-like protein 0.03318
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.03318
DLG1 discs, large homolog 1 (Drosophila) 0.03318
ANXA2 annexin A2 0.03318
JAM3 junctional adhesion molecule 3 0.03318
MARVELD2 MARVEL domain containing 2 0.03318
EXOC4 exocyst complex component 4 0.03318
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 0.03318