myelination Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. (Gene Ontology, GO_0042552)
External Link http://amigo.geneontology.org/amigo/term/GO:0042552
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Genes

51 genes participating in the myelination biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ACER3 alkaline ceramidase 3
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADGRG6 adhesion G protein-coupled receptor G6
AMIGO1 adhesion molecule with Ig-like domain 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BCAS1 breast carcinoma amplified sequence 1
CMTM8 CKLF-like MARVEL transmembrane domain containing 8
CNTNAP1 contactin associated protein 1
CXCR4 chemokine (C-X-C motif) receptor 4
DEGS1 delta(4)-desaturase, sphingolipid 1
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EPB41L3 erythrocyte membrane protein band 4.1-like 3
GAL3ST1 galactose-3-O-sulfotransferase 1
GPC1 glypican 1
GPM6B glycoprotein M6B
HES5 hes family bHLH transcription factor 5
HYCC1 hyccin PI4KA lipid kinase complex subunit 1
KLK6 kallikrein-related peptidase 6
LGI4 leucine-rich repeat LGI family, member 4
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene)
MALL mal, T-cell differentiation protein-like
MARVELD1 MARVEL domain containing 1
MPZ myelin protein zero
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYRF myelin regulatory factor
NF1 neurofibromin 1
NFASC neurofascin
PARD3 par-3 family cell polarity regulator
PLLP plasmolipin
PLP1 proteolipid protein 1
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PXMP2 peroxisomal membrane protein 2, 22kDa
SBF2 SET binding factor 2
SCN2A sodium channel, voltage gated, type II alpha subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SELENOI selenoprotein I
SIRT2 sirtuin 2
SKI SKI proto-oncogene
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SOX10 SRY (sex determining region Y)-box 10
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TMEM163 transmembrane protein 163
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPPP tubulin polymerization promoting protein
ZNF24 zinc finger protein 24