myocardial ischemia Gene Set

Dataset	GAD Gene-Disease Associations
Category	disease or phenotype associations
Type	disease
Description	Thickening and loss of elasticity of the CORONARY ARTERIES, leading to progressive arterial insufficiency (CORONARY DISEASE).\|Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.\|Narrowing of the coronary arteries due to fatty deposits inside the arterial walls.\|An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. (Experimental Factor Ontology, EFO_0000378)
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Genes

18 genes associated with the disease myocardial ischemia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol	Name
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1
ACE	angiotensin I converting enzyme
AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
APOA1	apolipoprotein A-I
APOB	apolipoprotein B
APOE	apolipoprotein E
CD14	CD14 molecule
CETP	cholesteryl ester transfer protein, plasma
F13A1	coagulation factor XIII, A1 polypeptide
F2	coagulation factor II (thrombin)
F5	coagulation factor V (proaccelerin, labile factor)
F7	coagulation factor VII (serum prothrombin conversion accelerator)
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
LIPC	lipase, hepatic
LPL	lipoprotein lipase
MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)
PCSK9	proprotein convertase subtilisin/kexin type 9
PON1	paraoxonase 1