myocarditis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An extrinsic cardiomyopathy that is characterized as an inflammation of the heart muscle. (Human Disease Ontology, DOID_820)
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Genes

308 genes co-occuring with the disease myocarditis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CD4 CD4 molecule 1.67232
TNNI3 troponin I type 3 (cardiac) 1.66825
CXADR coxsackie virus and adenovirus receptor 1.62336
TNNT2 troponin T type 2 (cardiac) 1.60726
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.53789
TNF tumor necrosis factor 1.37032
PRF1 perforin 1 (pore forming protein) 1.22128
ACE angiotensin I converting enzyme 1.22085
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 1.17164
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.15198
IL1B interleukin 1, beta 1.1422
IFNA6 interferon, alpha 6 1.12193
TSPO translocator protein (18kDa) 1.07908
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.01174
NPPA natriuretic peptide A 1.0033
SARDH sarcosine dehydrogenase 0.99908
CCL2 chemokine (C-C motif) ligand 2 0.994017
IL10 interleukin 10 0.989379
CD3D CD3d molecule, delta (CD3-TCR complex) 0.9839
CD1D CD1d molecule 0.956614
TLR3 toll-like receptor 3 0.94577
NOS2 nitric oxide synthase 2, inducible 0.944521
CRP C-reactive protein, pentraxin-related 0.911022
DMGDH dimethylglycine dehydrogenase 0.891308
IL12RB1 interleukin 12 receptor, beta 1 0.890488
TGFB1 transforming growth factor, beta 1 0.886389
IL2 interleukin 2 0.882292
IL17A interleukin 17A 0.868368
FOXP3 forkhead box P3 0.86714
ICAM1 intercellular adhesion molecule 1 0.859771
MMP9 matrix metallopeptidase 9 0.840934
TXN thioredoxin 0.835198
DMD dystrophin 0.834788
IL6 interleukin 6 0.831918
THY1 Thy-1 cell surface antigen 0.821667
MB myoglobin 0.818796
CCL3 chemokine (C-C motif) ligand 3 0.817155
FASLG Fas ligand (TNF superfamily, member 6) 0.808539
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.796642
NPPB natriuretic peptide B 0.764718
CD68 CD68 molecule 0.763902
IL4 interleukin 4 0.762678
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.762271
TLR4 toll-like receptor 4 0.747204
TNC tenascin C 0.734622
TTN titin 0.722482
IRF3 interferon regulatory factor 3 0.720461
MMP2 matrix metallopeptidase 2 0.717232
ZNF354B zinc finger protein 354B 0.703938
EDA ectodysplasin A 0.699116
CD276 CD276 molecule 0.696306
CD79A CD79a molecule, immunoglobulin-associated alpha 0.690694
HIST2H2AC histone cluster 2, H2ac 0.684292
HIST2H2AA4 histone cluster 2, H2aa4 0.683493
HIST2H2AA3 histone cluster 2, H2aa3 0.683493
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 0.66199
SOCS1 suppressor of cytokine signaling 1 0.661197
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.65288
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 0.651298
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.648928
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.641827
CCR1 chemokine (C-C motif) receptor 1 0.640251
TIMP1 TIMP metallopeptidase inhibitor 1 0.629635
NTSR1 neurotensin receptor 1 (high affinity) 0.628065
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.622575
VCAM1 vascular cell adhesion molecule 1 0.622183
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.61866
HLA-B major histocompatibility complex, class I, B 0.618268
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.616703
IFNB1 interferon, beta 1, fibroblast 0.614747
DNTT DNA nucleotidylexotransferase 0.610838
IFIH1 interferon induced with helicase C domain 1 0.606933
IL1A interleukin 1, alpha 0.59991
CA5B carbonic anhydrase VB, mitochondrial 0.594843
SPP1 secreted phosphoprotein 1 0.594064
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.579272
FBRS fibrosin 0.570329
FANCB Fanconi anemia, complementation group B 0.569552
SOD2 superoxide dismutase 2, mitochondrial 0.565277
STAT4 signal transducer and activator of transcription 4 0.564889
TMEM173 transmembrane protein 173 0.563335
TBX21 T-box 21 0.55945
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.553627
IFNA1 interferon, alpha 1 0.553239
CHM choroideremia (Rab escort protein 1) 0.545868
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 0.538506
CD70 CD70 molecule 0.525746
TLR8 toll-like receptor 8 0.52536
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.520731
COQ9 coenzyme Q9 0.518034
ADRB1 adrenoceptor beta 1 0.516494
GJA1 gap junction protein, alpha 1, 43kDa 0.514571
PDGFC platelet derived growth factor C 0.510728
CD8A CD8a molecule 0.509576
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 0.509192
JUP junction plakoglobin 0.507657
FN1 fibronectin 1 0.501144
CXCL10 chemokine (C-X-C motif) ligand 10 0.499614
CD86 CD86 molecule 0.499614
TREX1 three prime repair exonuclease 1 0.498467
CKMT1A creatine kinase, mitochondrial 1A 0.490835
FPGT fucose-1-phosphate guanylyltransferase 0.489691
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 0.484744
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.482844
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 0.482464
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.480186
JMY junction mediating and regulatory protein, p53 cofactor 0.471089
RNASEH2A ribonuclease H2, subunit A 0.470711
PKP2 plakophilin 2 0.466172
CKMT1B creatine kinase, mitochondrial 1B 0.465416
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 0.464283
RAG2 recombination activating gene 2 0.455978
LCK LCK proto-oncogene, Src family tyrosine kinase 0.450701
RPS20 ribosomal protein S20 0.445805
NOX4 NADPH oxidase 4 0.443923
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.443923
LY6E lymphocyte antigen 6 complex, locus E 0.443547
IRF9 interferon regulatory factor 9 0.442795
CTNS cystinosin, lysosomal cystine transporter 0.439034
CUX2 cut-like homeobox 2 0.436026
CD69 CD69 molecule 0.430768
CD40 CD40 molecule, TNF receptor superfamily member 5 0.430017
DSP desmoplakin 0.42664
ACTC1 actin, alpha, cardiac muscle 1 0.425139
NELFCD negative elongation factor complex member C/D 0.421765
TPM1 tropomyosin 1 (alpha) 0.420266
CD27 CD27 molecule 0.416896
ICOSLG inducible T-cell co-stimulator ligand 0.416521
GPX1 glutathione peroxidase 1 0.41465
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 0.412405
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.406798
LMNA lamin A/C 0.405678
CXCL9 chemokine (C-X-C motif) ligand 9 0.404184
HLA-E major histocompatibility complex, class I, E 0.401572
MYD88 myeloid differentiation primary response 88 0.401199
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.400453
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.399707
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.399334
RYR1 ryanodine receptor 1 (skeletal) 0.397098
CKB creatine kinase, brain 0.395608
CMA1 chymase 1, mast cell 0.393001
CCL5 chemokine (C-C motif) ligand 5 0.387051
RAG1 recombination activating gene 1 0.384822
MMP3 matrix metallopeptidase 3 0.374068
DLD dihydrolipoamide dehydrogenase 0.371477
DMBX1 diencephalon/mesencephalon homeobox 1 0.368518
DDIT3 DNA-damage-inducible transcript 3 0.365193
IFNA13 interferon, alpha 13 0.362239
CTGF connective tissue growth factor 0.359289
GATA4 GATA binding protein 4 0.35892
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.358551
FTMT ferritin mitochondrial 0.356709
IFNA5 interferon, alpha 5 0.353763
IFNA2 interferon, alpha 2 0.341639
SCGB1D2 secretoglobin, family 1D, member 2 0.340539
TLR9 toll-like receptor 9 0.340173
GPX5 glutathione peroxidase 5 0.335778
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 0.333583
GPX4 glutathione peroxidase 4 0.332487
NEBL nebulette 0.329565
IRF1 interferon regulatory factor 1 0.329565
IRF7 interferon regulatory factor 7 0.329565
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.32701
IL1RN interleukin 1 receptor antagonist 0.325916
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.325187
TDP2 tyrosyl-DNA phosphodiesterase 2 0.323002
OAT ornithine aminotransferase 0.320454
CD80 CD80 molecule 0.320454
SELE selectin E 0.32009
CKM creatine kinase, muscle 0.312464
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.311377
TP53BP2 tumor protein p53 binding protein 2 0.309566
DNAH8 dynein, axonemal, heavy chain 8 0.307033
RBMY1A1 RNA binding motif protein, Y-linked, family 1, member A1 0.30631
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.302698
CCL4 chemokine (C-C motif) ligand 4 0.300533
LGALS9 lectin, galactoside-binding, soluble, 9 0.297291
TLR2 toll-like receptor 2 0.295492
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.295492
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.295132
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.294053
ZC3H12A zinc finger CCCH-type containing 12A 0.292616
MAVS mitochondrial antiviral signaling protein 0.290462
TRAC T cell receptor alpha constant 0.285802
SCN5A sodium channel, voltage gated, type V alpha subunit 0.270108
HMGB1 high mobility group box 1 0.269753
PPARG peroxisome proliferator-activated receptor gamma 0.267267
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.266558
CCR2 chemokine (C-C motif) receptor 2 0.263368
FBXL15 F-box and leucine-rich repeat protein 15 0.261599
CCL13 chemokine (C-C motif) ligand 13 0.260538
ZNF148 zinc finger protein 148 0.25877
ILVBL ilvB (bacterial acetolactate synthase)-like 0.258064
CD40LG CD40 ligand 0.255241
ERH enhancer of rudimentary homolog (Drosophila) 0.253831
IGHV1-2 immunoglobulin heavy variable 1-2 0.248203
CAT catalase 0.246799
PDCD1 programmed cell death 1 0.245747
HRH1 histamine receptor H1 0.240497
ALB albumin 0.234225
NEXN nexilin (F actin binding protein) 0.229024
MYL12B myosin, light chain 12B, regulatory 0.228333
CD44 CD44 molecule (Indian blood group) 0.226607
GYLTL1B glycosyltransferase-like 1B 0.226607
ARSI arylsulfatase family, member I 0.226607
BAX BCL2-associated X protein 0.226607
F3 coagulation factor III (thromboplastin, tissue factor) 0.226262
GATA3 GATA binding protein 3 0.225229
CLMP CXADR-like membrane protein 0.224884
STAT2 signal transducer and activator of transcription 2, 113kDa 0.22454
AMY2A amylase, alpha 2A (pancreatic) 0.222822
GJB6 gap junction protein, beta 6, 30kDa 0.218374
CLC Charcot-Leyden crystal galectin 0.217012
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.217012
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.216672
CAV2 caveolin 2 0.216672
TRIM21 tripartite motif containing 21 0.215314
AKAP9 A kinase (PRKA) anchor protein 9 0.214975
PCBP2 poly(rC) binding protein 2 0.213959
ARR3 arrestin 3, retinal (X-arrestin) 0.211934
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.211261
EIF4B eukaryotic translation initiation factor 4B 0.208579
CSNK2B casein kinase 2, beta polypeptide 0.205585
SNTA1 syntrophin, alpha 1 0.201635
GDI2 GDP dissociation inhibitor 2 0.201308
TIMP4 TIMP metallopeptidase inhibitor 4 0.200331
RPTOR regulatory associated protein of MTOR, complex 1 0.200331
PLXNB1 plexin B1 0.198064
STAT1 signal transducer and activator of transcription 1, 91kDa 0.197099
JUN jun proto-oncogene 0.197099
ACTG1 actin gamma 1 0.195183
SIRPA signal-regulatory protein alpha 0.193285
NTF4 neurotrophin 4 0.191719
COL1A2 collagen, type I, alpha 2 0.190168
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.188938
RYR2 ryanodine receptor 2 (cardiac) 0.188326
IL17RA interleukin 17 receptor A 0.185016
DNASE2 deoxyribonuclease II, lysosomal 0.184128
FBXO2 F-box protein 2 0.184128
CIITA class II, major histocompatibility complex, transactivator 0.183248
LYZ lysozyme 0.182086
ACE2 angiotensin I converting enzyme 2 0.18151
ATP11A ATPase, class VI, type 11A 0.179239
CXCL8 chemokine (C-X-C motif) ligand 8 0.17896
DNA2 DNA replication helicase/nuclease 2 0.178682
IL27 interleukin 27 0.178126
CXCR3 chemokine (C-X-C motif) receptor 3 0.177576
GYPC glycophorin C (Gerbich blood group) 0.176215
PITX1 paired-like homeodomain 1 0.175947
VIL1 villin 1 0.175679
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.175146
IL22 interleukin 22 0.174881
POMC proopiomelanocortin 0.174617
ADAM23 ADAM metallopeptidase domain 23 0.173832
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.173314
PRRC2A proline-rich coiled-coil 2A 0.173314
GPR135 G protein-coupled receptor 135 0.172799
EDN1 endothelin 1 0.172544
ACSS2 acyl-CoA synthetase short-chain family member 2 0.172544
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 0.171535
HIST1H1A histone cluster 1, H1a 0.170789
IFNGR1 interferon gamma receptor 1 0.170544
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.168617
IL21 interleukin 21 0.166544
SORBS1 sorbin and SH3 domain containing 1 0.166544
B3GAT1 beta-1,3-glucuronyltransferase 1 0.165655
TMPRSS13 transmembrane protease, serine 13 0.163729
DLEC1 deleted in lung and esophageal cancer 1 0.162306
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.161331
BIN3 bridging integrator 3 0.160761
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.160387
DPP6 dipeptidyl-peptidase 6 0.157929
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.157929
ARF1 ADP-ribosylation factor 1 0.142675
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y 0.142345
GPR148 G protein-coupled receptor 148 0.136463
EOMES eomesodermin 0.135938
OSM oncostatin M 0.135764
LSR lipolysis stimulated lipoprotein receptor 0.134277
NPY neuropeptide Y 0.133789
RBMS1 RNA binding motif, single stranded interacting protein 1 0.130803
AIF1 allograft inflammatory factor 1 0.130661
CTF1 cardiotrophin 1 0.130629
ACPP acid phosphatase, prostate 0.130337
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.129987
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.12966
HTN3 histatin 3 0.128545
GNLY granulysin 0.127735
NEFM neurofilament, medium polypeptide 0.126431
HES5 hes family bHLH transcription factor 5 0.126182
PRIMA1 proline rich membrane anchor 1 0.125998
ADM adrenomedullin 0.125952
IL2RA interleukin 2 receptor, alpha 0.125837
FBXO17 F-box protein 17 0.122087
NOS3 nitric oxide synthase 3 (endothelial cell) 0.121851
NPPC natriuretic peptide C 0.121218
MRC1 mannose receptor, C type 1 0.119015
ARG1 arginase 1 0.118844
CD19 CD19 molecule 0.118463
GRB2 growth factor receptor-bound protein 2 0.117021
CISH cytokine inducible SH2-containing protein 0.116832
CCNE1 cyclin E1 0.115644
RPS6 ribosomal protein S6 0.113607
CAV3 caveolin 3 0.112837
VEGFA vascular endothelial growth factor A 0.11253
ALPPL2 alkaline phosphatase, placental-like 2 0.111008
ALPP alkaline phosphatase, placental 0.110961
ALPL alkaline phosphatase, liver/bone/kidney 0.110915