myofibril Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. (Gene Ontology, GO_0030016)
External Link http://amigo.geneontology.org/amigo/term/GO:0030016
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Genes

30 proteins localized to the myofibril cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
CAPN3 calpain 3, (p94)
DES desmin
LMOD1 leiomodin 1 (smooth muscle)
LMOD2 leiomodin 2 (cardiac)
LMOD3 leiomodin 3 (fetal)
MYBPC1 myosin binding protein C, slow type
MYBPC3 myosin binding protein C, cardiac
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYH4 myosin, heavy chain 4, skeletal muscle
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYL1 myosin, light chain 1, alkali; skeletal, fast
MYL12B myosin, light chain 12B, regulatory
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL7 myosin, light chain 7, regulatory
MYL9 myosin, light chain 9, regulatory
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PDE4DIP phosphodiesterase 4D interacting protein
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
SCO1 SCO1 cytochrome c oxidase assembly protein
SCO2 SCO2 cytochrome c oxidase assembly protein
TMOD1 tropomodulin 1
TMOD2 tropomodulin 2 (neuronal)
TMOD3 tropomodulin 3 (ubiquitous)
TMOD4 tropomodulin 4 (muscle)
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TWF1 twinfilin actin binding protein 1
TWF2 twinfilin actin binding protein 2