myofibroblast Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description An atypical fibroblast combining the ultrastructural features of a fibroblast and a smooth muscle cell; it has a highly irregular nucleus, a large amount of rough endoplasmic reticulum, and a dense collection of myofilaments. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001946)
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Genes

87 genes co-occuring with the biological term myofibroblast in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTG2 actin, gamma 2, smooth muscle, enteric
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALMS1 Alstrom syndrome protein 1
BMP6 bone morphogenetic protein 6
CLIC4 chloride intracellular channel 4
COL1A1 collagen, type I, alpha 1
CREB1 cAMP responsive element binding protein 1
CTF1 cardiotrophin 1
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DIAPH1 diaphanous-related formin 1
DIAPH3 diaphanous-related formin 3
EDN1 endothelin 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FGF1 fibroblast growth factor 1 (acidic)
FN1 fibronectin 1
GSK3B glycogen synthase kinase 3 beta
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IL1B interleukin 1, beta
ILK integrin-linked kinase
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LDHA lactate dehydrogenase A
LGALS3 lectin, galactoside-binding, soluble, 3
LRP1 low density lipoprotein receptor-related protein 1
MAPK14 mitogen-activated protein kinase 14
MECP2 methyl CpG binding protein 2
MEF2B myocyte enhancer factor 2B
MEOX2 mesenchyme homeobox 2
MIR145 microRNA 145
MIR146A microRNA 146a
MIR21 microRNA 21
MIR218-1 microRNA 218-1
MIR424 microRNA 424
MKL1 megakaryoblastic leukemia (translocation) 1
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MYC v-myc avian myelocytomatosis viral oncogene homolog
NES nestin
NGFR nerve growth factor receptor
NOX4 NADPH oxidase 4
NREP neuronal regeneration related protein
NRP1 neuropilin 1
PALLD palladin, cytoskeletal associated protein
PLAT plasminogen activator, tissue
PLAUR plasminogen activator, urokinase receptor
PLG plasminogen
POSTN periostin, osteoblast specific factor
PPARG peroxisome proliferator-activated receptor gamma
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTK2 protein tyrosine kinase 2
PURA purine-rich element binding protein A
PURB purine-rich element binding protein B
RHOA ras homolog family member A
RLN2 relaxin 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP1 secreted frizzled-related protein 1
SKI SKI proto-oncogene
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMAD7 SMAD family member 7
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNAI1 snail family zinc finger 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
TAGLN transgelin
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFBI transforming growth factor, beta-induced, 68kDa
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR9 toll-like receptor 9
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TNF tumor necrosis factor
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UNC119 unc-119 homolog (C. elegans)
VIM vimentin
WT1 Wilms tumor 1
XYLT1 xylosyltransferase I
ZEB1 zinc finger E-box binding homeobox 1