myopia Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness. (Experimental Factor Ontology, EFO_0003927)
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Genes

39 genes associated with the disease myopia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
BDNF brain-derived neurotrophic factor
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CHRM1 cholinergic receptor, muscarinic 1
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COL2A1 collagen, type II, alpha 1
CTNND2 catenin (cadherin-associated protein), delta 2
EGR1 early growth response 1
EPYC epiphycan
FGF2 fibroblast growth factor 2 (basic)
FMOD fibromodulin
GJD2 gap junction protein, delta 2, 36kDa
GRM6 glutamate receptor, metabotropic 6
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IRX1 iroquois homeobox 1
IRX2 iroquois homeobox 2
LUM lumican
MET MET proto-oncogene, receptor tyrosine kinase
MIPEP mitochondrial intermediate peptidase
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
OPTC opticin
PAPD7 PAP associated domain containing 7
PAX6 paired box 6
PRPH peripherin
RARB retinoic acid receptor, beta
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RDH8 retinol dehydrogenase 8 (all-trans)
SOX2 SRY (sex determining region Y)-box 2
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGIF1 TGFB-induced factor homeobox 1
UMODL1 uromodulin-like 1
ZNF831 zinc finger protein 831