myosmine-3634 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the myosmine-3634 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ACO2 aconitase 2, mitochondrial
ADD2 adducin 2 (beta)
ADRB3 adrenoceptor beta 3
AHNAK AHNAK nucleoprotein
ANGPTL2 angiopoietin-like 2
ANKMY1 ankyrin repeat and MYND domain containing 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AP3B2 adaptor-related protein complex 3, beta 2 subunit
AQP7 aquaporin 7
ARHGAP1 Rho GTPase activating protein 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATXN7L1 ataxin 7-like 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BMP6 bone morphogenetic protein 6
BNC2 basonuclin 2
C6 complement component 6
CALML3 calmodulin-like 3
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAPZB capping protein (actin filament) muscle Z-line, beta
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD177 CD177 molecule
CD1E CD1e molecule
CD58 CD58 molecule
CES3 carboxylesterase 3
CLIP2 CAP-GLY domain containing linker protein 2
COL1A2 collagen, type I, alpha 2
CSDC2 cold shock domain containing C2, RNA binding
CXCR4 chemokine (C-X-C motif) receptor 4
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DCN decorin
DST dystonin
ECE1 endothelin converting enzyme 1
EFNB3 ephrin-B3
EFR3B EFR3 homolog B (S. cerevisiae)
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERCC2 excision repair cross-complementation group 2
FAM182B family with sequence similarity 182, member B
FLOT1 flotillin 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GBP1 guanylate binding protein 1, interferon-inducible
GP2 glycoprotein 2 (zymogen granule membrane)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HDC histidine decarboxylase
HERC2P3 hect domain and RLD 2 pseudogene 3
HIPK2 homeodomain interacting protein kinase 2
HNRNPM heterogeneous nuclear ribonucleoprotein M
HR hair growth associated
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
ICAM2 intercellular adhesion molecule 2
IFI6 interferon, alpha-inducible protein 6
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IL1RN interleukin 1 receptor antagonist
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KIAA1109 KIAA1109
LCAT lecithin-cholesterol acyltransferase
LMNB1 lamin B1
LTBP4 latent transforming growth factor beta binding protein 4
LTC4S leukotriene C4 synthase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1A2 mannosidase, alpha, class 1A, member 2
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MN1 meningioma (disrupted in balanced translocation) 1
MR1 major histocompatibility complex, class I-related
MSMB microseminoprotein, beta-
MST1 macrophage stimulating 1
MYBPC3 myosin binding protein C, cardiac
NF1 neurofibromin 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRG2 neuregulin 2
OGFR opioid growth factor receptor
ORAI3 ORAI calcium release-activated calcium modulator 3
PALM paralemmin
PCDHB11 protocadherin beta 11
PCSK6 proprotein convertase subtilisin/kexin type 6
PKD1 polycystic kidney disease 1 (autosomal dominant)
PNLIPRP2 pancreatic lipase-related protein 2
PTK2B protein tyrosine kinase 2 beta
RAG2 recombination activating gene 2
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RHEB Ras homolog enriched in brain
RND1 Rho family GTPase 1
RRBP1 ribosome binding protein 1
SCGN secretagogin, EF-hand calcium binding protein
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SLC30A3 solute carrier family 30 (zinc transporter), member 3
STMN3 stathmin-like 3
STS steroid sulfatase (microsomal), isozyme S
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TUBBP5 tubulin, beta pseudogene 5
VSX1 visual system homeobox 1
WDR62 WD repeat domain 62
WSCD1 WSC domain containing 1
ZNF471 zinc finger protein 471

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTL8 actin-like 8
ANKRD36 ankyrin repeat domain 36
APLP1 amyloid beta (A4) precursor-like protein 1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGAP4 Rho GTPase activating protein 4
ARID3B AT rich interactive domain 3B (BRIGHT-like)
C2ORF27A chromosome 2 open reading frame 27A
C2ORF68 chromosome 2 open reading frame 68
C8ORF60 chromosome 8 open reading frame 60
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC121 coiled-coil domain containing 121
CCNK cyclin K
CCP110 centriolar coiled coil protein 110kDa
CGREF1 cell growth regulator with EF-hand domain 1
CHKB choline kinase beta
CHRM3 cholinergic receptor, muscarinic 3
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CLGN calmegin
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNGB3 cyclic nucleotide gated channel beta 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNPY4 canopy FGF signaling regulator 4
CRY2 cryptochrome circadian clock 2
CSTA cystatin A (stefin A)
CTRL chymotrypsin-like
CTSF cathepsin F
CXXC4 CXXC finger protein 4
DEAF1 DEAF1 transcription factor
DEPDC5 DEP domain containing 5
DNAH7 dynein, axonemal, heavy chain 7
DOK5 docking protein 5
DUSP2 dual specificity phosphatase 2
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPN1 epsin 1
EPPK1 epiplakin 1
ETV7 ets variant 7
FAM46C family with sequence similarity 46, member C
FBXL7 F-box and leucine-rich repeat protein 7
FLJ22184
FRMD1 FERM domain containing 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GK3P glycerol kinase 3 pseudogene
GLDC glycine dehydrogenase (decarboxylating)
GNG13 guanine nucleotide binding protein (G protein), gamma 13
HDAC7 histone deacetylase 7
HIST1H4E histone cluster 1, H4e
HIST2H2AA3 histone cluster 2, H2aa3
HOXC8 homeobox C8
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYAL1 hyaluronoglucosaminidase 1
IL18 interleukin 18
IRX4 iroquois homeobox 4
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCTD17 potassium channel tetramerization domain containing 17
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LARP6 La ribonucleoprotein domain family, member 6
LIME1 Lck interacting transmembrane adaptor 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAGEA5 melanoma antigen family A5
MRPL41 mitochondrial ribosomal protein L41
ONECUT2 one cut homeobox 2
PCDHA5 protocadherin alpha 5
PDE12 phosphodiesterase 12
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
POPDC3 popeye domain containing 3
PTDSS2 phosphatidylserine synthase 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASL11B RAS-like, family 11, member B
RCAN3 RCAN family member 3
REM1 RAS (RAD and GEM)-like GTP-binding 1
RPL10L ribosomal protein L10-like
SLN sarcolipin
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNTA1 syntrophin, alpha 1
SREK1IP1 SREK1-interacting protein 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STIM1 stromal interaction molecule 1
TBKBP1 TBK1 binding protein 1
THBS3 thrombospondin 3
TMEM19 transmembrane protein 19
TRDMT1 tRNA aspartic acid methyltransferase 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN5 tetraspanin 5
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TWISTNB TWIST neighbor
VIPR1 vasoactive intestinal peptide receptor 1
ZNF10 zinc finger protein 10
ZNF696 zinc finger protein 696
ZNRD1-AS1 ZNRD1 antisense RNA 1
ZSCAN2 zinc finger and SCAN domain containing 2