myosmine-3737 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the myosmine-3737 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACOXL acyl-CoA oxidase-like
ADAM22 ADAM metallopeptidase domain 22
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BBC3 BCL2 binding component 3
BMP10 bone morphogenetic protein 10
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF16 chromosome 11 open reading frame 16
C14ORF79 chromosome 14 open reading frame 79
CCDC177 coiled-coil domain containing 177
CCPG1 cell cycle progression 1
CD40 CD40 molecule, TNF receptor superfamily member 5
CD58 CD58 molecule
CDC25C cell division cycle 25C
CDRT1 CMT1A duplicated region transcript 1
CFAP70 cilia and flagella associated protein 70
CHM choroideremia (Rab escort protein 1)
CLCN4 chloride channel, voltage-sensitive 4
CLDN11 claudin 11
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DKFZP434C153 DKFZP434C153 protein
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DTNA dystrobrevin, alpha
EMP1 epithelial membrane protein 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
GK glycerol kinase
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GRIK5 glutamate receptor, ionotropic, kainate 5
GRM7 glutamate receptor, metabotropic 7
HAND1 heart and neural crest derivatives expressed 1
HBE1 hemoglobin, epsilon 1
HCG4B HLA complex group 4B (non-protein coding)
HIST1H2AB histone cluster 1, H2ab
HIST1H3I histone cluster 1, H3i
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IGF1R insulin-like growth factor 1 receptor
IL11 interleukin 11
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
JADE2 jade family PHD finger 2
KAT8 K(lysine) acetyltransferase 8
KCNIP1 Kv channel interacting protein 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KDM4C lysine (K)-specific demethylase 4C
KIAA1109 KIAA1109
KIDINS220 kinase D-interacting substrate, 220kDa
KIF1A kinesin family member 1A
KRT17 keratin 17, type I
LDHC lactate dehydrogenase C
LIMK2 LIM domain kinase 2
LTBP4 latent transforming growth factor beta binding protein 4
MEF2D myocyte enhancer factor 2D
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
NAG18 NAG18 mRNA
NAV3 neuron navigator 3
NDRG2 NDRG family member 2
NRP2 neuropilin 2
ONECUT2 one cut homeobox 2
ORAI2 ORAI calcium release-activated calcium modulator 2
OSBP2 oxysterol binding protein 2
OVOL1 ovo-like zinc finger 1
PAWR PRKC, apoptosis, WT1, regulator
PDCD2 programmed cell death 2
PDE2A phosphodiesterase 2A, cGMP-stimulated
PHF3 PHD finger protein 3
PICALM phosphatidylinositol binding clathrin assembly protein
PMFBP1 polyamine modulated factor 1 binding protein 1
POU2F3 POU class 2 homeobox 3
PRKCA protein kinase C, alpha
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RAB6B RAB6B, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAD52 RAD52 homolog (S. cerevisiae)
RANBP1 RAN binding protein 1
RECQL5 RecQ protein-like 5
RHAG Rh-associated glycoprotein
RNF146 ring finger protein 146
RPL35A ribosomal protein L35a
SCN3B sodium channel, voltage gated, type III beta subunit
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERHL2 serine hydrolase-like 2
SLAMF7 SLAM family member 7
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SSX3 synovial sarcoma, X breakpoint 3
SYCE1L synaptonemal complex central element protein 1-like
SYT5 synaptotagmin V
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBL1Y transducin (beta)-like 1, Y-linked
TJAP1 tight junction associated protein 1 (peripheral)
TMOD1 tropomodulin 1
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TUBA3C tubulin, alpha 3c
UBR4 ubiquitin protein ligase E3 component n-recognin 4
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADGRB2 adhesion G protein-coupled receptor B2
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
APH1A APH1A gamma secretase subunit
ARHGAP22 Rho GTPase activating protein 22
ARPIN actin-related protein 2/3 complex inhibitor
BAX BCL2-associated X protein
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF105 chromosome 1 open reading frame 105
C1ORF54 chromosome 1 open reading frame 54
C3 complement component 3
C5 complement component 5
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC7 coiled-coil domain containing 7
CD79B CD79b molecule, immunoglobulin-associated beta
CEP41 centrosomal protein 41kDa
CGREF1 cell growth regulator with EF-hand domain 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CINP cyclin-dependent kinase 2 interacting protein
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNTN1 contactin 1
COL16A1 collagen, type XVI, alpha 1
DENND2D DENN/MADD domain containing 2D
DPF3 D4, zinc and double PHD fingers, family 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGR2 early growth response 2
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELSPBP1 epididymal sperm binding protein 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FGF1 fibroblast growth factor 1 (acidic)
H1F0 H1 histone family, member 0
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRA histone cell cycle regulator
HIST1H2BM histone cluster 1, H2bm
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFI44L interferon-induced protein 44-like
IFNA14 interferon, alpha 14
JAM3 junctional adhesion molecule 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIFC1 kinesin family member C1
KIRREL kin of IRRE like (Drosophila)
KLF3 Kruppel-like factor 3 (basic)
KRT4 keratin 4, type II
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC257152 uncharacterized LOC257152
LPAR3 lysophosphatidic acid receptor 3
MAGEA5 melanoma antigen family A5
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED31 mediator complex subunit 31
MED9 mediator complex subunit 9
NEK11 NIMA-related kinase 11
NID2 nidogen 2 (osteonidogen)
NPFFR1 neuropeptide FF receptor 1
PGLYRP4 peptidoglycan recognition protein 4
PID1 phosphotyrosine interaction domain containing 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRAMEF10 PRAME family member 10
PRSS53 protease, serine, 53
RAB36 RAB36, member RAS oncogene family
RHBDD3 rhomboid domain containing 3
RNF121 ring finger protein 121
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SDC3 syndecan 3
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIX3 SIX homeobox 3
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPIDR scaffolding protein involved in DNA repair
SYNGR3 synaptogyrin 3
TBC1D2 TBC1 domain family, member 2
THRAP3 thyroid hormone receptor associated protein 3
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAC T cell receptor alpha constant
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIM25 tripartite motif containing 25
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TXK TXK tyrosine kinase
VGLL3 vestigial-like family member 3
WDR62 WD repeat domain 62
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF222 zinc finger protein 222
ZNF268 zinc finger protein 268
ZNF749 zinc finger protein 749