myosmine-4293 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the myosmine-4293 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ADCK2 aarF domain containing kinase 2
ADGRA2 adhesion G protein-coupled receptor A2
ADGRL3 adhesion G protein-coupled receptor L3
AFF2 AF4/FMR2 family, member 2
AGRN agrin
AGTR1 angiotensin II receptor, type 1
ARHGAP28 Rho GTPase activating protein 28
ATP11A ATPase, class VI, type 11A
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C10ORF10 chromosome 10 open reading frame 10
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCKAR cholecystokinin A receptor
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD4 CD4 molecule
CD58 CD58 molecule
CD84 CD84 molecule
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
COL11A1 collagen, type XI, alpha 1
COL16A1 collagen, type XVI, alpha 1
CPA2 carboxypeptidase A2 (pancreatic)
DBP D site of albumin promoter (albumin D-box) binding protein
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EGR1 early growth response 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FGF4 fibroblast growth factor 4
FLJ11292
FYB FYN binding protein
GALC galactosylceramidase
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GHRHR growth hormone releasing hormone receptor
GLI2 GLI family zinc finger 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR135 G protein-coupled receptor 135
GRK4 G protein-coupled receptor kinase 4
HIST1H1D histone cluster 1, H1d
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMGN5 high mobility group nucleosome binding domain 5
HNF1B HNF1 homeobox B
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KIAA1654 KIAA1654 protein
KLC2 kinesin light chain 2
KLK7 kallikrein-related peptidase 7
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMO4 LIM domain only 4
LOC440895 two pore channel 3 pseudogene
LOXL3 lysyl oxidase-like 3
MAP7D3 MAP7 domain containing 3
MTMR7 myotubularin related protein 7
MUC8 mucin 8
NOS2 nitric oxide synthase 2, inducible
NTM neurotrimin
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PCDH11X protocadherin 11 X-linked
PCDH11Y protocadherin 11 Y-linked
PDE3A phosphodiesterase 3A, cGMP-inhibited
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
POFUT2 protein O-fucosyltransferase 2
PQLC2 PQ loop repeat containing 2
PRAF2 PRA1 domain family, member 2
PRKG2 protein kinase, cGMP-dependent, type II
PSG9 pregnancy specific beta-1-glycoprotein 9
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBMY2FP RNA binding motif protein, Y-linked, family 2, member F pseudogene
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF126P1 ring finger protein 126 pseudogene 1
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SHOX2 short stature homeobox 2
SMC1A structural maintenance of chromosomes 1A
SRRT serrate, RNA effector molecule
SRSF7 serine/arginine-rich splicing factor 7
SUGP1 SURP and G patch domain containing 1
TBL1Y transducin (beta)-like 1, Y-linked
TCF4 transcription factor 4
TESPA1 thymocyte expressed, positive selection associated 1
TMEM212 transmembrane protein 212
TNNT2 troponin T type 2 (cardiac)
TONSL tonsoku-like, DNA repair protein
TRA T cell receptor alpha locus
TSC22D2 TSC22 domain family, member 2
TTC39A tetratricopeptide repeat domain 39A
TUBA3C tubulin, alpha 3c
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
USH2A Usher syndrome 2A (autosomal recessive, mild)
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VAMP5 vesicle-associated membrane protein 5
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
YBX2 Y box binding protein 2
ZNF154 zinc finger protein 154
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
AK5 adenylate kinase 5
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
AURKC aurora kinase C
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAHD1 bromo adjacent homology domain containing 1
BEND5 BEN domain containing 5
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C11ORF21 chromosome 11 open reading frame 21
C17ORF80 chromosome 17 open reading frame 80
C4ORF29 chromosome 4 open reading frame 29
CD82 CD82 molecule
CDH7 cadherin 7, type 2
CHM choroideremia (Rab escort protein 1)
CIDEB cell death-inducing DFFA-like effector b
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COL21A1 collagen, type XXI, alpha 1
CORT cortistatin
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DMBT1 deleted in malignant brain tumors 1
DNM3 dynamin 3
ELSPBP1 epididymal sperm binding protein 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EYA4 EYA transcriptional coactivator and phosphatase 4
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJC1 gap junction protein, gamma 1, 45kDa
GSTCD glutathione S-transferase, C-terminal domain containing
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXA7 homeobox A7
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IL6 interleukin 6
KIAA0319L KIAA0319-like
KIF13A kinesin family member 13A
KLF13 Kruppel-like factor 13
KLF3 Kruppel-like factor 3 (basic)
KLK5 kallikrein-related peptidase 5
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LPAR3 lysophosphatidic acid receptor 3
LRRC15 leucine rich repeat containing 15
LRRC61 leucine rich repeat containing 61
LY96 lymphocyte antigen 96
MED31 mediator complex subunit 31
MLYCD malonyl-CoA decarboxylase
MMP3 matrix metallopeptidase 3
MTCP1 mature T-cell proliferation 1
MXD3 MAX dimerization protein 3
MYL10 myosin, light chain 10, regulatory
NECAP2 NECAP endocytosis associated 2
NOL6 nucleolar protein 6 (RNA-associated)
NTSR1 neurotensin receptor 1 (high affinity)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
ODF2 outer dense fiber of sperm tails 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OSGIN1 oxidative stress induced growth inhibitor 1
OSMR oncostatin M receptor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RCOR3 REST corepressor 3
RGS17 regulator of G-protein signaling 17
RHOBTB2 Rho-related BTB domain containing 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF122 ring finger protein 122
RPGRIP1L RPGRIP1-like
RPP25 ribonuclease P/MRP 25kDa subunit
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RWDD2A RWD domain containing 2A
SCGB2A2 secretoglobin, family 2A, member 2
SENP7 SUMO1/sentrin specific peptidase 7
SETD8 SET domain containing (lysine methyltransferase) 8
SLC25A40 solute carrier family 25, member 40
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX21 SRY (sex determining region Y)-box 21
SPIDR scaffolding protein involved in DNA repair
SPTBN2 spectrin, beta, non-erythrocytic 2
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBXAS1 thromboxane A synthase 1 (platelet)
TCTN1 tectonic family member 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLN1 talin 1
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TSC22D4 TSC22 domain family, member 4
TSPAN32 tetraspanin 32
WDR33 WD repeat domain 33
XAF1 XIAP associated factor 1
YY2 YY2 transcription factor
ZNF141 zinc finger protein 141
ZNF219 zinc finger protein 219
ZNF222 zinc finger protein 222