myosmine-4759 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the myosmine-4759 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACO2 aconitase 2, mitochondrial
ACTG2 actin, gamma 2, smooth muscle, enteric
ADM adrenomedullin
AEBP1 AE binding protein 1
AJAP1 adherens junctions associated protein 1
AKAP1 A kinase (PRKA) anchor protein 1
AKR1C1 aldo-keto reductase family 1, member C1
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
APC adenomatous polyposis coli
APOC1 apolipoprotein C-I
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C1QTNF3 C1q and tumor necrosis factor related protein 3
C21ORF2 chromosome 21 open reading frame 2
CA1 carbonic anhydrase I
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCDC64 coiled-coil domain containing 64
CD22 CD22 molecule
CD48 CD48 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CLIC5 chloride intracellular channel 5
CLTB clathrin, light chain B
COL1A1 collagen, type I, alpha 1
COPZ2 coatomer protein complex, subunit zeta 2
DCN decorin
DGCR8 DGCR8 microprocessor complex subunit
DMPK dystrophia myotonica-protein kinase
DST dystonin
EPHB1 EPH receptor B1
FAM188A family with sequence similarity 188, member A
FBXO2 F-box protein 2
FGF18 fibroblast growth factor 18
FYB FYN binding protein
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GIMAP6 GTPase, IMAP family member 6
GPNMB glycoprotein (transmembrane) nmb
GPR75 G protein-coupled receptor 75
GRB10 growth factor receptor-bound protein 10
GREB1L growth regulation by estrogen in breast cancer-like
HAO2 hydroxyacid oxidase 2 (long chain)
HHAT hedgehog acyltransferase
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOXA11 homeobox A11
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
ICA1 islet cell autoantigen 1, 69kDa
IGFBP5 insulin-like growth factor binding protein 5
IGLJ3 immunoglobulin lambda joining 3
IL11 interleukin 11
INO80D INO80 complex subunit D
KRAS Kirsten rat sarcoma viral oncogene homolog
LIMCH1 LIM and calponin homology domains 1
MAPK7 mitogen-activated protein kinase 7
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MYCNOS MYCN opposite strand
N4BP2L1 NEDD4 binding protein 2-like 1
NCR2 natural cytotoxicity triggering receptor 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRSN2 neurensin 2
OGFR opioid growth factor receptor
PCDH1 protocadherin 1
PDGFA platelet-derived growth factor alpha polypeptide
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLXNA2 plexin A2
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PVRL3 poliovirus receptor-related 3
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAB40C RAB40C, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIN3 Ras and Rab interactor 3
RPH3A rabphilin 3A
S100A7 S100 calcium binding protein A7
SAA3P serum amyloid A3 pseudogene
SAG S-antigen; retina and pineal gland (arrestin)
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SH3GL3 SH3-domain GRB2-like 3
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SPON2 spondin 2, extracellular matrix protein
SSTR4 somatostatin receptor 4
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TBL1X transducin (beta)-like 1X-linked
TBR1 T-box, brain, 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TOR4A torsin family 4, member A
UNC5B unc-5 homolog B (C. elegans)
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WNT16 wingless-type MMTV integration site family, member 16
WNT6 wingless-type MMTV integration site family, member 6
XDH xanthine dehydrogenase
ZFP64 ZFP64 zinc finger protein
ZNF701 zinc finger protein 701

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADAP2 ArfGAP with dual PH domains 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ARMC6 armadillo repeat containing 6
AUTS2 autism susceptibility candidate 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BFSP1 beaded filament structural protein 1, filensin
C14ORF79 chromosome 14 open reading frame 79
C6ORF47 chromosome 6 open reading frame 47
CCDC121 coiled-coil domain containing 121
CCDC85C coiled-coil domain containing 85C
CCP110 centriolar coiled coil protein 110kDa
CCRL2 chemokine (C-C motif) receptor-like 2
CD83 CD83 molecule
CDK20 cyclin-dependent kinase 20
CENPO centromere protein O
CLCN6 chloride channel, voltage-sensitive 6
CLEC7A C-type lectin domain family 7, member A
CLGN calmegin
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DMTN dematin actin binding protein
DPY19L1P1 DPY19L1 pseudogene 1
DYSF dysferlin
ELSPBP1 epididymal sperm binding protein 1
ERCC6 excision repair cross-complementation group 6
FAM110B family with sequence similarity 110, member B
FGF23 fibroblast growth factor 23
FKBP5 FK506 binding protein 5
FLJ11710 uncharacterized protein FLJ11710
FMOD fibromodulin
GJA9 gap junction protein, alpha 9, 59kDa
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
INPP5J inositol polyphosphate-5-phosphatase J
IQSEC2 IQ motif and Sec7 domain 2
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KLF7 Kruppel-like factor 7 (ubiquitous)
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LHX1 LIM homeobox 1
LINC01587 long intergenic non-protein coding RNA 1587
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC100286895 cell division cycle 27 homolog pseudogene
MFGE8 milk fat globule-EGF factor 8 protein
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MRPS18C mitochondrial ribosomal protein S18C
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAX9 paired box 9
PCDHA5 protocadherin alpha 5
PCDHB13 protocadherin beta 13
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G3 phospholipase A2, group III
PLAT plasminogen activator, tissue
POLL polymerase (DNA directed), lambda
PTK6 protein tyrosine kinase 6
QSER1 glutamine and serine rich 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF31 ring finger protein 31
RNF39 ring finger protein 39
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A9 S100 calcium binding protein A9
SAYSD1 SAYSVFN motif domain containing 1
SCG2 secretogranin II
SCGB2A2 secretoglobin, family 2A, member 2
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERGEF secretion regulating guanine nucleotide exchange factor
SIGLEC15 sialic acid binding Ig-like lectin 15
SIPA1 signal-induced proliferation-associated 1
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SMR3A submaxillary gland androgen regulated protein 3A
SREK1IP1 SREK1-interacting protein 1
STEAP4 STEAP family member 4
SYBU syntabulin (syntaxin-interacting)
TARP TCR gamma alternate reading frame protein
TCTN2 tectonic family member 2
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THBS3 thrombospondin 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM120B transmembrane protein 120B
TMEM180 transmembrane protein 180
TMEM212 transmembrane protein 212
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XYLT2 xylosyltransferase II
ZFHX4 zinc finger homeobox 4
ZMAT5 zinc finger, matrin-type 5
ZNF37BP zinc finger protein 37B, pseudogene