myosmine-6055 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the myosmine-6055 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ADAM12 ADAM metallopeptidase domain 12
ADAM22 ADAM metallopeptidase domain 22
ADRA1A adrenoceptor alpha 1A
AMT aminomethyltransferase
APOC1 apolipoprotein C-I
ASIC3 acid sensing (proton gated) ion channel 3
ATN1 atrophin 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BCAM basal cell adhesion molecule (Lutheran blood group)
BIN1 bridging integrator 1
C19ORF66 chromosome 19 open reading frame 66
CARF calcium responsive transcription factor
CCDC64 coiled-coil domain containing 64
CD36 CD36 molecule (thrombospondin receptor)
CLCN7 chloride channel, voltage-sensitive 7
CLEC4M C-type lectin domain family 4, member M
CLPS colipase, pancreatic
CORO2B coronin, actin binding protein, 2B
CPEB1 cytoplasmic polyadenylation element binding protein 1
CSTA cystatin A (stefin A)
DFNA5 deafness, autosomal dominant 5
DFNB31 deafness, autosomal recessive 31
DSC2 desmocollin 2
DUSP13 dual specificity phosphatase 13
ECE1 endothelin converting enzyme 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELL2 elongation factor, RNA polymerase II, 2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERO1LB ERO1-like beta (S. cerevisiae)
EZR ezrin
FBXL7 F-box and leucine-rich repeat protein 7
FHIT fragile histidine triad
GABARAPL1 GABA(A) receptor-associated protein like 1
GALR2 galanin receptor 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
IL1RN interleukin 1 receptor antagonist
ING2 inhibitor of growth family, member 2
INTS1 integrator complex subunit 1
ITGA8 integrin, alpha 8
ITM2C integral membrane protein 2C
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLF13 Kruppel-like factor 13
KMT2A lysine (K)-specific methyltransferase 2A
LAMP1 lysosomal-associated membrane protein 1
LAT2 linker for activation of T cells family, member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIPF lipase, gastric
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MBD2 methyl-CpG binding domain protein 2
MED25 mediator complex subunit 25
MYBPC3 myosin binding protein C, cardiac
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NOX1 NADPH oxidase 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
NYNRIN NYN domain and retroviral integrase containing
OPCML opioid binding protein/cell adhesion molecule-like
PCM1 pericentriolar material 1
PDE9A phosphodiesterase 9A
PDLIM7 PDZ and LIM domain 7 (enigma)
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PKP1 plakophilin 1
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PSG3 pregnancy specific beta-1-glycoprotein 3
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PVR poliovirus receptor
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SATB2 SATB homeobox 2
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC25A30 solute carrier family 25, member 30
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOCS3 suppressor of cytokine signaling 3
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPON1 spondin 1, extracellular matrix protein
SULT4A1 sulfotransferase family 4A, member 1
TCF12 transcription factor 12
TDRD12 tudor domain containing 12
TNXB tenascin XB
TRAK1 trafficking protein, kinesin binding 1
TRIM49 tripartite motif containing 49
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
WNT8B wingless-type MMTV integration site family, member 8B
ZFP36L1 ZFP36 ring finger protein-like 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTL8 actin-like 8
ALS2CL ALS2 C-terminal like
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BTF3P12 basic transcription factor 3 pseudogene 12
C9ORF9 chromosome 9 open reading frame 9
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAPG capping protein (actin filament), gelsolin-like
CCDC132 coiled-coil domain containing 132
CD34 CD34 molecule
CD83 CD83 molecule
CD8A CD8a molecule
CDK3 cyclin-dependent kinase 3
CDON cell adhesion associated, oncogene regulated
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLCN6 chloride channel, voltage-sensitive 6
CLDN17 claudin 17
CNR2 cannabinoid receptor 2 (macrophage)
CNTFR ciliary neurotrophic factor receptor
COPZ2 coatomer protein complex, subunit zeta 2
CTSF cathepsin F
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DES desmin
DGAT1 diacylglycerol O-acyltransferase 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELSPBP1 epididymal sperm binding protein 1
EN2 engrailed homeobox 2
ENO3 enolase 3 (beta, muscle)
EXD3 exonuclease 3'-5' domain containing 3
EXOSC1 exosome component 1
FKBP10 FK506 binding protein 10, 65 kDa
GRPR gastrin-releasing peptide receptor
HDAC5 histone deacetylase 5
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BO histone cluster 1, H2bo
HIST2H2AA3 histone cluster 2, H2aa3
HOXA4 homeobox A4
HOXC5 homeobox C5
IDI2-AS1 IDI2 antisense RNA 1
IL2RB interleukin 2 receptor, beta
IRF6 interferon regulatory factor 6
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNK12 potassium channel, two pore domain subfamily K, member 12
KREMEN2 kringle containing transmembrane protein 2
KRT16 keratin 16, type I
LMX1B LIM homeobox transcription factor 1, beta
LRP5L low density lipoprotein receptor-related protein 5-like
MAP2 microtubule-associated protein 2
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MSI1 musashi RNA-binding protein 1
MXRA8 matrix-remodelling associated 8
NDOR1 NADPH dependent diflavin oxidoreductase 1
NEUROD4 neuronal differentiation 4
NOL10 nucleolar protein 10
NPR3 natriuretic peptide receptor 3
PADI1 peptidyl arginine deiminase, type I
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLCD1 phospholipase C, delta 1
PODNL1 podocan-like 1
POM121 POM121 transmembrane nucleoporin
PQLC2 PQ loop repeat containing 2
QSER1 glutamine and serine rich 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD52 RAD52 homolog (S. cerevisiae)
RFTN1 raftlin, lipid raft linker 1
RIN1 Ras and Rab interactor 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL10L ribosomal protein L10-like
SAA4 serum amyloid A4, constitutive
SEC14L5 SEC14-like 5 (S. cerevisiae)
SH2D4A SH2 domain containing 4A
SLC17A2 solute carrier family 17, member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SNTG1 syntrophin, gamma 1
SPINK5 serine peptidase inhibitor, Kazal type 5
TBC1D19 TBC1 domain family, member 19
TESC tescalcin
TEX40 testis expressed 40
TMEM242 transmembrane protein 242
TRAF2 TNF receptor-associated factor 2
UPK2 uroplakin 2
USB1 U6 snRNA biogenesis 1
WDR78 WD repeat domain 78
WFDC2 WAP four-disulfide core domain 2
WNT2 wingless-type MMTV integration site family member 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YY2 YY2 transcription factor
ZC3H3 zinc finger CCCH-type containing 3
ZNF16 zinc finger protein 16
ZNF219 zinc finger protein 219
ZNF304 zinc finger protein 304
ZNF507 zinc finger protein 507