| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the nabumetone-3108 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALOX5 | arachidonate 5-lipoxygenase |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ATP10B | ATPase, class V, type 10B |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BMP15 | bone morphogenetic protein 15 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CALML3 | calmodulin-like 3 |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CAPN3 | calpain 3, (p94) |
| CCDC106 | coiled-coil domain containing 106 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COPE | coatomer protein complex, subunit epsilon |
| CRYM | crystallin, mu |
| CSN3 | casein kappa |
| CTC1 | CTS telomere maintenance complex component 1 |
| CUX1 | cut-like homeobox 1 |
| CYHR1 | cysteine/histidine-rich 1 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DOCK9 | dedicator of cytokinesis 9 |
| DPP4 | dipeptidyl-peptidase 4 |
| ECE1 | endothelin converting enzyme 1 |
| EFNA5 | ephrin-A5 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
| FADS3 | fatty acid desaturase 3 |
| FAM102A | family with sequence similarity 102, member A |
| FAM186A | family with sequence similarity 186, member A |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FBXO4 | F-box protein 4 |
| FN1 | fibronectin 1 |
| FOXG1 | forkhead box G1 |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GAS6 | growth arrest-specific 6 |
| GAS8 | growth arrest-specific 8 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| HAB1 | B1 for mucin |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IL22RA1 | interleukin 22 receptor, alpha 1 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| ITPKA | inositol-trisphosphate 3-kinase A |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KLF12 | Kruppel-like factor 12 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| MRPL20 | mitochondrial ribosomal protein L20 |
| MXD4 | MAX dimerization protein 4 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NPEPL1 | aminopeptidase-like 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRP1 | neuropilin 1 |
| NUP188 | nucleoporin 188kDa |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHA2 | protocadherin alpha 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDLIM4 | PDZ and LIM domain 4 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PORCN | porcupine homolog (Drosophila) |
| POU2F2 | POU class 2 homeobox 2 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB26 | RAB26, member RAS oncogene family |
| RECQL5 | RecQ protein-like 5 |
| RPL10 | ribosomal protein L10 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SLAMF8 | SLAM family member 8 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TBXA2R | thromboxane A2 receptor |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TEX40 | testis expressed 40 |
| TF | transferrin |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| USB1 | U6 snRNA biogenesis 1 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF446 | zinc finger protein 446 |
| ZNF696 | zinc finger protein 696 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACPP | acid phosphatase, prostate |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ARRB1 | arrestin, beta 1 |
| B3GNT1 | |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CBX7 | chromobox homolog 7 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHM | choroideremia (Rab escort protein 1) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ETV4 | ets variant 4 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FCHO1 | FCH domain only 1 |
| FHIT | fragile histidine triad |
| FNBP1L | formin binding protein 1-like |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GAA | glucosidase, alpha; acid |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPX2 | glutathione peroxidase 2 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H3G | histone cluster 1, H3g |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| ISOC2 | isochorismatase domain containing 2 |
| JUNB | jun B proto-oncogene |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KPTN | kaptin (actin binding protein) |
| LIMD2 | LIM domain containing 2 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MLPH | melanophilin |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYBPH | myosin binding protein H |
| MYO1E | myosin IE |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NIPAL2 | NIPA-like domain containing 2 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PARG | poly (ADP-ribose) glycohydrolase |
| PDE12 | phosphodiesterase 12 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLCB4 | phospholipase C, beta 4 |
| PLCD1 | phospholipase C, delta 1 |
| PLTP | phospholipid transfer protein |
| POM121 | POM121 transmembrane nucleoporin |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| RAB23 | RAB23, member RAS oncogene family |
| RAB33A | RAB33A, member RAS oncogene family |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF141 | ring finger protein 141 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RWDD2A | RWD domain containing 2A |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC35F6 | solute carrier family 35, member F6 |
| SPON2 | spondin 2, extracellular matrix protein |
| TERT | telomerase reverse transcriptase |
| TESK1 | testis-specific kinase 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TOM1 | target of myb1 (chicken) |
| TRAF2 | TNF receptor-associated factor 2 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 |
| TSPAN13 | tetraspanin 13 |
| TTC23 | tetratricopeptide repeat domain 23 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR33 | WD repeat domain 33 |
| XAB2 | XPA binding protein 2 |
| YY2 | YY2 transcription factor |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF155 | zinc finger protein 155 |
| ZNF280B | zinc finger protein 280B |
| ZNF408 | zinc finger protein 408 |
