| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the nabumetone-6487 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ATN1 | atrophin 1 |
| BGN | biglycan |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C2 | complement component 2 |
| CADM3 | cell adhesion molecule 3 |
| CALML3 | calmodulin-like 3 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CCDC181 | coiled-coil domain containing 181 |
| CD52 | CD52 molecule |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| COL4A1 | collagen, type IV, alpha 1 |
| CST1 | cystatin SN |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| DENND5B | DENN/MADD domain containing 5B |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DTNA | dystrobrevin, alpha |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FCAR | Fc fragment of IgA receptor |
| FGF18 | fibroblast growth factor 18 |
| GLUL | glutamate-ammonia ligase |
| GMPR | guanosine monophosphate reductase |
| GREM2 | gremlin 2, DAN family BMP antagonist |
| GRM4 | glutamate receptor, metabotropic 4 |
| HDAC5 | histone deacetylase 5 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2BC | histone cluster 1, H2bc |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HR | hair growth associated |
| HRASLS2 | HRAS-like suppressor 2 |
| HRH3 | histamine receptor H3 |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| INHBE | inhibin, beta E |
| IQCA1 | IQ motif containing with AAA domain 1 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| KIF5A | kinesin family member 5A |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KRT83 | keratin 83, type II |
| LEP | leptin |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LILRP2 | leukocyte immunoglobulin-like receptor pseudogene 2 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MR1 | major histocompatibility complex, class I-related |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NTN1 | netrin 1 |
| OLFM4 | olfactomedin 4 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited |
| PNPLA2 | patatin-like phospholipase domain containing 2 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTRF | polymerase I and transcript release factor |
| RAP2B | RAP2B, member of RAS oncogene family |
| RBP4 | retinol binding protein 4, plasma |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUNX1 | runt-related transcription factor 1 |
| SASH3 | SAM and SH3 domain containing 3 |
| SC5D | sterol-C5-desaturase |
| SCARA3 | scavenger receptor class A, member 3 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC13A4 | solute carrier family 13 (sodium/sulfate symporter), member 4 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SMIM14 | small integral membrane protein 14 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TFR2 | transferrin receptor 2 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNS1 | tensin 1 |
| VNN1 | vanin 1 |
| WDR91 | WD repeat domain 91 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZCCHC4 | zinc finger, CCHC domain containing 4 |
| ZNF223 | zinc finger protein 223 |
| ZNF318 | zinc finger protein 318 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACYP2 | acylphosphatase 2, muscle type |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ADM | adrenomedullin |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BAGE | B melanoma antigen |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CBR3 | carbonyl reductase 3 |
| CBR4 | carbonyl reductase 4 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD82 | CD82 molecule |
| CIDEC | cell death-inducing DFFA-like effector c |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLDND1 | claudin domain containing 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CSTA | cystatin A (stefin A) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DENND4A | DENN/MADD domain containing 4A |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| EGFL7 | EGF-like-domain, multiple 7 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERCC6 | excision repair cross-complementation group 6 |
| FAAH | fatty acid amide hydrolase |
| FAM120C | family with sequence similarity 120C |
| FBXO31 | F-box protein 31 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPATCH3 | G patch domain containing 3 |
| GPR87 | G protein-coupled receptor 87 |
| GPX2 | glutathione peroxidase 2 |
| GRPR | gastrin-releasing peptide receptor |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HAMP | hepcidin antimicrobial peptide |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H4A | histone cluster 1, H4a |
| HIST1H4F | histone cluster 1, H4f |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HOXA4 | homeobox A4 |
| HOXB2 | homeobox B2 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| JMJD4 | jumonji domain containing 4 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA1456 | KIAA1456 |
| KLHL25 | kelch-like family member 25 |
| KLK5 | kallikrein-related peptidase 5 |
| KPTN | kaptin (actin binding protein) |
| KRT8P12 | keratin 8 pseudogene 12 |
| LENEP | lens epithelial protein |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC729164 | hCG1732469 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCC | mutated in colorectal cancers |
| MGC12488 | |
| OLFML2A | olfactomedin-like 2A |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PITX2 | paired-like homeodomain 2 |
| PLA2G15 | phospholipase A2, group XV |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RANGRF | RAN guanine nucleotide release factor |
| RASA2 | RAS p21 protein activator 2 |
| REEP4 | receptor accessory protein 4 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF31 | ring finger protein 31 |
| SCAI | suppressor of cancer cell invasion |
| SH2D4A | SH2 domain containing 4A |
| SLC41A3 | solute carrier family 41, member 3 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STAG3 | stromal antigen 3 |
| STK16 | serine/threonine kinase 16 |
| STON1 | stonin 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCTA | T-cell leukemia translocation altered |
| TET3 | tet methylcytosine dioxygenase 3 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TRAIP | TRAF interacting protein |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UEVLD | UEV and lactate/malate dehyrogenase domains |
| WDR4 | WD repeat domain 4 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF16 | zinc finger protein 16 |
| ZNF226 | zinc finger protein 226 |
| ZNF665 | zinc finger protein 665 |
| ZNF770 | zinc finger protein 770 |
| ZNF862 | zinc finger protein 862 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
