nadide-5873 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the nadide-5873 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACE2 angiotensin I converting enzyme 2
AGO4 argonaute RISC catalytic component 4
AIM2 absent in melanoma 2
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AQP3 aquaporin 3 (Gill blood group)
ARL14 ADP-ribosylation factor-like 14
ATF7IP activating transcription factor 7 interacting protein
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
CABIN1 calcineurin binding protein 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC85B coiled-coil domain containing 85B
CDHR2 cadherin-related family member 2
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEMIP cell migration inducing protein, hyaluronan binding
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
COL9A2 collagen, type IX, alpha 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYTH1 cytohesin 1
DMBT1 deleted in malignant brain tumors 1
DNPEP aspartyl aminopeptidase
DSCAM Down syndrome cell adhesion molecule
EPHA4 EPH receptor A4
EPHA5 EPH receptor A5
EYA4 EYA transcriptional coactivator and phosphatase 4
GLRA1 glycine receptor, alpha 1
GNS glucosamine (N-acetyl)-6-sulfatase
GPR19 G protein-coupled receptor 19
HIRA histone cell cycle regulator
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IFT140 intraflagellar transport 140
IGFBP5 insulin-like growth factor binding protein 5
IGHM immunoglobulin heavy constant mu
IL11 interleukin 11
IL15RA interleukin 15 receptor, alpha
IL7 interleukin 7
IRX4 iroquois homeobox 4
KIF5C kinesin family member 5C
KRT6A keratin 6A, type II
LATS1 large tumor suppressor kinase 1
LIPG lipase, endothelial
LMF1 lipase maturation factor 1
LPAR6 lysophosphatidic acid receptor 6
LRP1 low density lipoprotein receptor-related protein 1
LRRK1 leucine-rich repeat kinase 1
MAP7 microtubule-associated protein 7
MAPK10 mitogen-activated protein kinase 10
MED25 mediator complex subunit 25
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MT3 metallothionein 3
MUC1 mucin 1, cell surface associated
NMRK2 nicotinamide riboside kinase 2
NPFF neuropeptide FF-amide peptide precursor
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PHF8 PHD finger protein 8
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKP4 plakophilin 4
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRR3 proline rich 3
PRRC2B proline-rich coiled-coil 2B
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
RARG retinoic acid receptor, gamma
RASAL2 RAS protein activator like 2
REEP2 receptor accessory protein 2
SAA4 serum amyloid A4, constitutive
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPHK2 sphingosine kinase 2
SPTBN1 spectrin, beta, non-erythrocytic 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TAT tyrosine aminotransferase
TBL2 transducin (beta)-like 2
TBR1 T-box, brain, 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TSPAN31 tetraspanin 31
TXNRD3 thioredoxin reductase 3
UNC45A unc-45 homolog A (C. elegans)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WIPF1 WAS/WASL interacting protein family, member 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZIC3 Zic family member 3
ZNF219 zinc finger protein 219
ZNF222 zinc finger protein 222
ZNF385D zinc finger protein 385D
ZNF467 zinc finger protein 467
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP1AR adaptor-related protein complex 1 associated regulatory protein
AP3M2 adaptor-related protein complex 3, mu 2 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ASAP1-IT1 ASAP1 intronic transcript 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
AZI2 5-azacytidine induced 2
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAHD1 bromo adjacent homology domain containing 1
BIRC3 baculoviral IAP repeat containing 3
C11ORF63 chromosome 11 open reading frame 63
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
C4ORF29 chromosome 4 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CCDC106 coiled-coil domain containing 106
CCDC68 coiled-coil domain containing 68
CCNJ cyclin J
CCNT1 cyclin T1
CDKN2AIP CDKN2A interacting protein
CFAP44 cilia and flagella associated protein 44
CHMP6 charged multivesicular body protein 6
COG7 component of oligomeric golgi complex 7
DCAF13 DDB1 and CUL4 associated factor 13
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EAF2 ELL associated factor 2
EFNA3 ephrin-A3
EN1 engrailed homeobox 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM155A family with sequence similarity 155, member A
FAM53B family with sequence similarity 53, member B
FANCE Fanconi anemia, complementation group E
FBXL6 F-box and leucine-rich repeat protein 6
FKBP1B FK506 binding protein 1B, 12.6 kDa
GLCE glucuronic acid epimerase
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HAMP hepcidin antimicrobial peptide
HELZ helicase with zinc finger
HIST1H2AE histone cluster 1, H2ae
HIST1H2AG histone cluster 1, H2ag
HIST1H2AJ histone cluster 1, H2aj
HIST1H3C histone cluster 1, H3c
IFNA14 interferon, alpha 14
IRAK4 interleukin-1 receptor-associated kinase 4
LRRC37A3 leucine rich repeat containing 37, member A3
MCTP1 multiple C2 domains, transmembrane 1
MOGS mannosyl-oligosaccharide glucosidase
MOXD1 monooxygenase, DBH-like 1
NDE1 nudE neurodevelopment protein 1
NPM3 nucleophosmin/nucleoplasmin 3
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRGN neurogranin (protein kinase C substrate, RC3)
PAN2 PAN2 poly(A) specific ribonuclease subunit
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLAC8 placenta-specific 8
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PRMT7 protein arginine methyltransferase 7
PRSS22 protease, serine, 22
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAI2 retinoic acid induced 2
RGCC regulator of cell cycle
RPL10L ribosomal protein L10-like
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCAMP5 secretory carrier membrane protein 5
SCN1B sodium channel, voltage gated, type I beta subunit
SH3BGR SH3 domain binding glutamate-rich protein
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SMAD7 SMAD family member 7
SND1-IT1 SND1 intronic transcript 1
SNORA21 small nucleolar RNA, H/ACA box 21
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TMCC2 transmembrane and coiled-coil domain family 2
TMEM115 transmembrane protein 115
TMEM209 transmembrane protein 209
TMEM57 transmembrane protein 57
TMEM8A transmembrane protein 8A
TRAIP TRAF interacting protein
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTBK2 tau tubulin kinase 2
ZNF253 zinc finger protein 253
ZNF324 zinc finger protein 324
ZNF329 zinc finger protein 329
ZNF408 zinc finger protein 408
ZNF442 zinc finger protein 442
ZNF552 zinc finger protein 552
ZNF675 zinc finger protein 675
ZNHIT2 zinc finger, HIT-type containing 2