nadide-7227 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the nadide-7227 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADGRG1 adhesion G protein-coupled receptor G1
AMPD3 adenosine monophosphate deaminase 3
AQP3 aquaporin 3 (Gill blood group)
ARMCX4 armadillo repeat containing, X-linked 4
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BIRC3 baculoviral IAP repeat containing 3
C14ORF105 chromosome 14 open reading frame 105
CCDC64 coiled-coil domain containing 64
CD40 CD40 molecule, TNF receptor superfamily member 5
CD52 CD52 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEP164 centrosomal protein 164kDa
CFHR4 complement factor H-related 4
CHKB choline kinase beta
CHST10 carbohydrate sulfotransferase 10
CNPY4 canopy FGF signaling regulator 4
CPD carboxypeptidase D
CSTA cystatin A (stefin A)
CXCR4 chemokine (C-X-C motif) receptor 4
DLX4 distal-less homeobox 4
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
ERAP1 endoplasmic reticulum aminopeptidase 1
EXO5 exonuclease 5
FLT4 fms-related tyrosine kinase 4
FRMD4B FERM domain containing 4B
FUS FUS RNA binding protein
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GRM8 glutamate receptor, metabotropic 8
GSTA1 glutathione S-transferase alpha 1
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IL12RB1 interleukin 12 receptor, beta 1
IL22 interleukin 22
INE1 inactivation escape 1 (non-protein coding)
IRS4 insulin receptor substrate 4
ITGB4 integrin, beta 4
JPH3 junctophilin 3
KDM5B lysine (K)-specific demethylase 5B
KIAA0319L KIAA0319-like
KLHL22 kelch-like family member 22
KRT31 keratin 31, type I
LAMB4 laminin, beta 4
LRP12 low density lipoprotein receptor-related protein 12
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MIIP migration and invasion inhibitory protein
MPPE1 metallophosphoesterase 1
MTA1 metastasis associated 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NMUR1 neuromedin U receptor 1
NUMA1 nuclear mitotic apparatus protein 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
ORAI2 ORAI calcium release-activated calcium modulator 2
PCGF3 polycomb group ring finger 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POU1F1 POU class 1 homeobox 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTCRA pre T-cell antigen receptor alpha
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAB11B RAB11B, member RAS oncogene family
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBM12B RNA binding motif protein 12B
RPS4Y1 ribosomal protein S4, Y-linked 1
SCAPER S-phase cyclin A-associated protein in the ER
SCN2B sodium channel, voltage gated, type II beta subunit
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SMR3A submaxillary gland androgen regulated protein 3A
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPRED2 sprouty-related, EVH1 domain containing 2
SRSF7 serine/arginine-rich splicing factor 7
SSPN sarcospan
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAT tyrosine aminotransferase
TLE4 transducin-like enhancer of split 4
TMEM209 transmembrane protein 209
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRIM29 tripartite motif containing 29
USP2 ubiquitin specific peptidase 2
VPRBP Vpr (HIV-1) binding protein
VPS9D1 VPS9 domain containing 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZNF286A zinc finger protein 286A
ZNF415 zinc finger protein 415
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862
ZNF93 zinc finger protein 93
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
AGBL5 ATP/GTP binding protein-like 5
ASPHD1 aspartate beta-hydroxylase domain containing 1
C7ORF43 chromosome 7 open reading frame 43
CAPG capping protein (actin filament), gelsolin-like
CDKL3 cyclin-dependent kinase-like 3
CENPJ centromere protein J
CFAP69 cilia and flagella associated protein 69
CIDEC cell death-inducing DFFA-like effector c
CRYL1 crystallin, lambda 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNA2 DNA replication helicase/nuclease 2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
F3 coagulation factor III (thromboplastin, tissue factor)
FAM169A family with sequence similarity 169, member A
FBXO2 F-box protein 2
FEM1C fem-1 homolog c (C. elegans)
FRS2 fibroblast growth factor receptor substrate 2
FSD1 fibronectin type III and SPRY domain containing 1
GAB2 GRB2-associated binding protein 2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNL1 guanine nucleotide binding protein-like 1
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H2AJ histone cluster 1, H2aj
IFNA14 interferon, alpha 14
IFT81 intraflagellar transport 81
IGFBP6 insulin-like growth factor binding protein 6
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL4R interleukin 4 receptor
IMPACT impact RWD domain protein
IP6K1 inositol hexakisphosphate kinase 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF6 interferon regulatory factor 6
ISG20 interferon stimulated exonuclease gene 20kDa
KLF7 Kruppel-like factor 7 (ubiquitous)
KRT13 keratin 13, type I
LAMA3 laminin, alpha 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LINC00115 long intergenic non-protein coding RNA 115
LOC730101 uncharacterized LOC730101
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC20 leucine rich repeat containing 20
MAST3 microtubule associated serine/threonine kinase 3
MBIP MAP3K12 binding inhibitory protein 1
MORC3 MORC family CW-type zinc finger 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTMR12 myotubularin related protein 12
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NCAM2 neural cell adhesion molecule 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFE2L3 nuclear factor, erythroid 2-like 3
NRSN2 neurensin 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PARD6A par-6 family cell polarity regulator alpha
PDE12 phosphodiesterase 12
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGPEP1 pyroglutamyl-peptidase I
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
RGS17 regulator of G-protein signaling 17
RIBC2 RIB43A domain with coiled-coils 2
RNF31 ring finger protein 31
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SCD5 stearoyl-CoA desaturase 5
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SFT2D2 SFT2 domain containing 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPINK4 serine peptidase inhibitor, Kazal type 4
SSFA2 sperm specific antigen 2
STRN striatin, calmodulin binding protein
SUN2 Sad1 and UNC84 domain containing 2
SYCP2 synaptonemal complex protein 2
TH tyrosine hydroxylase
THRAP3 thyroid hormone receptor associated protein 3
TMEM254 transmembrane protein 254
TMEM53 transmembrane protein 53
TMUB2 transmembrane and ubiquitin-like domain containing 2
TOM1 target of myb1 (chicken)
TRABD TraB domain containing
TRAIP TRAF interacting protein
TSPAN1 tetraspanin 1
TTC26 tetratricopeptide repeat domain 26
UBXN6 UBX domain protein 6
USP27X ubiquitin specific peptidase 27, X-linked
WRAP73 WD repeat containing, antisense to TP73
XYLT2 xylosyltransferase II
ZBTB6 zinc finger and BTB domain containing 6
ZC3H12A zinc finger CCCH-type containing 12A
ZFP69B ZFP69 zinc finger protein B
ZMAT5 zinc finger, matrin-type 5
ZNF14 zinc finger protein 14
ZNF250 zinc finger protein 250
ZNF573 zinc finger protein 573
ZNF8 zinc finger protein 8
ZNF816 zinc finger protein 816