| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the nadide-7227 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| CCDC64 | coiled-coil domain containing 64 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CD52 | CD52 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CEP164 | centrosomal protein 164kDa |
| CFHR4 | complement factor H-related 4 |
| CHKB | choline kinase beta |
| CHST10 | carbohydrate sulfotransferase 10 |
| CNPY4 | canopy FGF signaling regulator 4 |
| CPD | carboxypeptidase D |
| CSTA | cystatin A (stefin A) |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DLX4 | distal-less homeobox 4 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| EXO5 | exonuclease 5 |
| FLT4 | fms-related tyrosine kinase 4 |
| FRMD4B | FERM domain containing 4B |
| FUS | FUS RNA binding protein |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GRM8 | glutamate receptor, metabotropic 8 |
| GSTA1 | glutathione S-transferase alpha 1 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL22 | interleukin 22 |
| INE1 | inactivation escape 1 (non-protein coding) |
| IRS4 | insulin receptor substrate 4 |
| ITGB4 | integrin, beta 4 |
| JPH3 | junctophilin 3 |
| KDM5B | lysine (K)-specific demethylase 5B |
| KIAA0319L | KIAA0319-like |
| KLHL22 | kelch-like family member 22 |
| KRT31 | keratin 31, type I |
| LAMB4 | laminin, beta 4 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MIIP | migration and invasion inhibitory protein |
| MPPE1 | metallophosphoesterase 1 |
| MTA1 | metastasis associated 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NF1 | neurofibromin 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NMUR1 | neuromedin U receptor 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PCGF3 | polycomb group ring finger 3 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POU1F1 | POU class 1 homeobox 1 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PTCRA | pre T-cell antigen receptor alpha |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RAB11B | RAB11B, member RAS oncogene family |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RBM12B | RNA binding motif protein 12B |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SCN2B | sodium channel, voltage gated, type II beta subunit |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SSPN | sarcospan |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TAT | tyrosine aminotransferase |
| TLE4 | transducin-like enhancer of split 4 |
| TMEM209 | transmembrane protein 209 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRIM29 | tripartite motif containing 29 |
| USP2 | ubiquitin specific peptidase 2 |
| VPRBP | Vpr (HIV-1) binding protein |
| VPS9D1 | VPS9 domain containing 1 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZNF286A | zinc finger protein 286A |
| ZNF415 | zinc finger protein 415 |
| ZNF76 | zinc finger protein 76 |
| ZNF862 | zinc finger protein 862 |
| ZNF93 | zinc finger protein 93 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| AGBL5 | ATP/GTP binding protein-like 5 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CENPJ | centromere protein J |
| CFAP69 | cilia and flagella associated protein 69 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CRYL1 | crystallin, lambda 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNA2 | DNA replication helicase/nuclease 2 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM169A | family with sequence similarity 169, member A |
| FBXO2 | F-box protein 2 |
| FEM1C | fem-1 homolog c (C. elegans) |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GNL1 | guanine nucleotide binding protein-like 1 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIST1H2AJ | histone cluster 1, H2aj |
| IFNA14 | interferon, alpha 14 |
| IFT81 | intraflagellar transport 81 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL4R | interleukin 4 receptor |
| IMPACT | impact RWD domain protein |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRF6 | interferon regulatory factor 6 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KRT13 | keratin 13, type I |
| LAMA3 | laminin, alpha 3 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LOC730101 | uncharacterized LOC730101 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LRRC20 | leucine rich repeat containing 20 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTMR12 | myotubularin related protein 12 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) |
| NCAM2 | neural cell adhesion molecule 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NRSN2 | neurensin 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDE12 | phosphodiesterase 12 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| RGS17 | regulator of G-protein signaling 17 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF31 | ring finger protein 31 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SFT2D2 | SFT2 domain containing 2 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SSFA2 | sperm specific antigen 2 |
| STRN | striatin, calmodulin binding protein |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SYCP2 | synaptonemal complex protein 2 |
| TH | tyrosine hydroxylase |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM254 | transmembrane protein 254 |
| TMEM53 | transmembrane protein 53 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TOM1 | target of myb1 (chicken) |
| TRABD | TraB domain containing |
| TRAIP | TRAF interacting protein |
| TSPAN1 | tetraspanin 1 |
| TTC26 | tetratricopeptide repeat domain 26 |
| UBXN6 | UBX domain protein 6 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WRAP73 | WD repeat containing, antisense to TP73 |
| XYLT2 | xylosyltransferase II |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZFP69B | ZFP69 zinc finger protein B |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF14 | zinc finger protein 14 |
| ZNF250 | zinc finger protein 250 |
| ZNF573 | zinc finger protein 573 |
| ZNF8 | zinc finger protein 8 |
| ZNF816 | zinc finger protein 816 |