| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the nadolol-4139 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| ADRB3 | adrenoceptor beta 3 |
| AGFG1 | ArfGAP with FG repeats 1 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ATN1 | atrophin 1 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C9ORF116 | chromosome 9 open reading frame 116 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CCDC68 | coiled-coil domain containing 68 |
| CD58 | CD58 molecule |
| CDC14A | cell division cycle 14A |
| CEP112 | centrosomal protein 112kDa |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLGN | calmegin |
| CPT2 | carnitine palmitoyltransferase 2 |
| CYB561 | cytochrome b561 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EPOR | erythropoietin receptor |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FAM89B | family with sequence similarity 89, member B |
| FBXO21 | F-box protein 21 |
| FJX1 | four jointed box 1 (Drosophila) |
| FLOT1 | flotillin 1 |
| GALR3 | galanin receptor 3 |
| GK | glycerol kinase |
| GPR137 | G protein-coupled receptor 137 |
| GRK5 | G protein-coupled receptor kinase 5 |
| H2AFX | H2A histone family, member X |
| HIST1H4E | histone cluster 1, H4e |
| HNMT | histamine N-methyltransferase |
| HPX | hemopexin |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IL17RC | interleukin 17 receptor C |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KIAA0319L | KIAA0319-like |
| KIAA1107 | KIAA1107 |
| KLHDC4 | kelch domain containing 4 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LEPR | leptin receptor |
| LIMCH1 | LIM and calponin homology domains 1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAPK7 | mitogen-activated protein kinase 7 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED25 | mediator complex subunit 25 |
| METTL16 | methyltransferase like 16 |
| MOB1A | MOB kinase activator 1A |
| MR1 | major histocompatibility complex, class I-related |
| MTMR8 | myotubularin related protein 8 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NCOR2 | nuclear receptor corepressor 2 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NF1 | neurofibromin 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| NRTN | neurturin |
| PCNX | pecanex homolog (Drosophila) |
| PEG10 | paternally expressed 10 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B |
| PROS1 | protein S (alpha) |
| PTGDR2 | prostaglandin D2 receptor 2 |
| RBM12 | RNA binding motif protein 12 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| RSU1 | Ras suppressor protein 1 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SKI | SKI proto-oncogene |
| SLC35E2 | solute carrier family 35, member E2 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| SOAT1 | sterol O-acyltransferase 1 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TDRD12 | tudor domain containing 12 |
| TGFB2 | transforming growth factor, beta 2 |
| THAP9 | THAP domain containing 9 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMEM5 | transmembrane protein 5 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRIM23 | tripartite motif containing 23 |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF155 | zinc finger protein 155 |
| ZNF350 | zinc finger protein 350 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| AMPH | amphiphysin |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| ARSE | arylsulfatase E (chondrodysplasia punctata 1) |
| ART1 | ADP-ribosyltransferase 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD82 | CD82 molecule |
| CFAP45 | cilia and flagella associated protein 45 |
| CFHR4 | complement factor H-related 4 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| EPYC | epiphycan |
| ETNK2 | ethanolamine kinase 2 |
| FLCN | folliculin |
| FSTL1 | follistatin-like 1 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GRIP2 | glutamate receptor interacting protein 2 |
| HAS2 | hyaluronan synthase 2 |
| HHAT | hedgehog acyltransferase |
| HIST1H2AK | histone cluster 1, H2ak |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HMOX1 | heme oxygenase 1 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IBSP | integrin-binding sialoprotein |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IQCA1 | IQ motif containing with AAA domain 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA1456 | KIAA1456 |
| KLF13 | Kruppel-like factor 13 |
| LEFTY2 | left-right determination factor 2 |
| LOC100131510 | uncharacterized LOC100131510 |
| LOC79999 | uncharacterized LOC79999 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRC48 | leucine rich repeat containing 48 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MYO15A | myosin XVA |
| NAG18 | NAG18 mRNA |
| NELL2 | NEL-like 2 (chicken) |
| NEUROD1 | neuronal differentiation 1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| OCA2 | oculocutaneous albinism II |
| PCDHB13 | protocadherin beta 13 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PICK1 | protein interacting with PRKCA 1 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLCD1 | phospholipase C, delta 1 |
| POLH | polymerase (DNA directed), eta |
| POLL | polymerase (DNA directed), lambda |
| PRDM14 | PR domain containing 14 |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| PXDC1 | PX domain containing 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RGS9 | regulator of G-protein signaling 9 |
| RHBDD3 | rhomboid domain containing 3 |
| RIMBP2 | RIMS binding protein 2 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPL10L | ribosomal protein L10-like |
| RPL34 | ribosomal protein L34 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SLC14A2 | solute carrier family 14 (urea transporter), member 2 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SPRR1B | small proline-rich protein 1B |
| TAGLN3 | transgelin 3 |
| TAOK1 | TAO kinase 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TEP1 | telomerase-associated protein 1 |
| UBQLN4 | ubiquilin 4 |
| UCN | urocortin |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZFHX4 | zinc finger homeobox 4 |
| ZMAT4 | zinc finger, matrin-type 4 |