nafcillin-2983 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the nafcillin-2983 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD2 adducin 2 (beta)
ADORA1 adenosine A1 receptor
AFF3 AF4/FMR2 family, member 3
APLP2 amyloid beta (A4) precursor-like protein 2
APOD apolipoprotein D
ATXN2L ataxin 2-like
BANK1 B-cell scaffold protein with ankyrin repeats 1
BLZF1 basic leucine zipper nuclear factor 1
BTG3 BTG family, member 3
CAMP cathelicidin antimicrobial peptide
CDK19 cyclin-dependent kinase 19
CHMP6 charged multivesicular body protein 6
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNS cystinosin, lysosomal cystine transporter
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DCN decorin
DGAT1 diacylglycerol O-acyltransferase 1
DGKA diacylglycerol kinase, alpha 80kDa
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FCMR Fc fragment of IgM receptor
FDPS farnesyl diphosphate synthase
FGFR3 fibroblast growth factor receptor 3
FOXF1 forkhead box F1
GK3P glycerol kinase 3 pseudogene
GRAMD1B GRAM domain containing 1B
GRIA3 glutamate receptor, ionotropic, AMPA 3
HEXIM1 hexamethylene bis-acetamide inducible 1
HIST1H2BC histone cluster 1, H2bc
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGL immunoglobulin lambda locus
IL1R2 interleukin 1 receptor, type II
IL4 interleukin 4
INCENP inner centromere protein antigens 135/155kDa
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KLF5 Kruppel-like factor 5 (intestinal)
KLHL22 kelch-like family member 22
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LINC00216 long intergenic non-protein coding RNA 216
LPAR1 lysophosphatidic acid receptor 1
MAGEA6 melanoma antigen family A6
MET MET proto-oncogene, receptor tyrosine kinase
MFAP3L microfibrillar-associated protein 3-like
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MPZL1 myelin protein zero-like 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NINL ninein-like
NOL10 nucleolar protein 10
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRP1 neuropilin 1
NTN3 netrin 3
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PLCL1 phospholipase C-like 1
PRAMEF12 PRAME family member 12
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRSS8 protease, serine, 8
PRUNE prune exopolyphosphatase
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RDX radixin
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RHBDD3 rhomboid domain containing 3
RHBG Rh family, B glycoprotein (gene/pseudogene)
RNASE3 ribonuclease, RNase A family, 3
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPL23AP53 ribosomal protein L23a pseudogene 53
RPL23AP7 ribosomal protein L23a pseudogene 7
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SETD1B SET domain containing 1B
SLC12A8 solute carrier family 12, member 8
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SMAD5 SMAD family member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNPH syntaphilin
SSBP2 single-stranded DNA binding protein 2
STC1 stanniocalcin 1
STEAP4 STEAP family member 4
TPM3 tropomyosin 3
TRPS1 trichorhinophalangeal syndrome I
TSC2 tuberous sclerosis 2
TSPAN9 tetraspanin 9
UGT8 UDP glycosyltransferase 8
YOD1 YOD1 deubiquitinase
ZBTB20 zinc finger and BTB domain containing 20
ZNF214 zinc finger protein 214
ZNF225 zinc finger protein 225
ZNF492 zinc finger protein 492
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANO2 anoctamin 2, calcium activated chloride channel
ANXA3 annexin A3
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOC4 apolipoprotein C-IV
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF16 chromosome 11 open reading frame 16
C3ORF18 chromosome 3 open reading frame 18
C5AR1 complement component 5a receptor 1
CABP2 calcium binding protein 2
CAPN15 calpain 15
CASS4 Cas scaffolding protein family member 4
CCDC85C coiled-coil domain containing 85C
CDHR2 cadherin-related family member 2
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CPTP ceramide-1-phosphate transfer protein
CRYGC crystallin, gamma C
CST1 cystatin SN
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDN dendrin
DSCAM Down syndrome cell adhesion molecule
DTX4 deltex 4, E3 ubiquitin ligase
EBF2 early B-cell factor 2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FRMPD1 FERM and PDZ domain containing 1
FRS3 fibroblast growth factor receptor substrate 3
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPR35 G protein-coupled receptor 35
GSDMD gasdermin D
GUCA2A guanylate cyclase activator 2A (guanylin)
HDAC7 histone deacetylase 7
HIST1H1D histone cluster 1, H1d
HIST1H1T histone cluster 1, H1t
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BN histone cluster 1, H2bn
HOXB9 homeobox B9
HOXC10 homeobox C10
HPR haptoglobin-related protein
HYAL2 hyaluronoglucosaminidase 2
IFNA14 interferon, alpha 14
IGH immunoglobulin heavy locus
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KLK11 kallikrein-related peptidase 11
KRT12 keratin 12, type I
KRT20 keratin 20, type I
LTA lymphotoxin alpha
LTBP2 latent transforming growth factor beta binding protein 2
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MTSS1L metastasis suppressor 1-like
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
NCKAP1L NCK-associated protein 1-like
NINJ2 ninjurin 2
NMUR1 neuromedin U receptor 1
NPPB natriuretic peptide B
NSUN6 NOP2/Sun domain family, member 6
NTSR1 neurotensin receptor 1 (high affinity)
OCLN occludin
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PBOV1 prostate and breast cancer overexpressed 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIP prolactin-induced protein
PLAT plasminogen activator, tissue
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
POLH polymerase (DNA directed), eta
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRR7 proline rich 7 (synaptic)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RCAN3 RCAN family member 3
SCRT1 scratch family zinc finger 1
SH2D4A SH2 domain containing 4A
SIGLEC15 sialic acid binding Ig-like lectin 15
SIX3 SIX homeobox 3
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC16A6 solute carrier family 16, member 6
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCHH trichohyalin
TCTN2 tectonic family member 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFDP3 transcription factor Dp family, member 3
TMC5 transmembrane channel-like 5
TMEM206 transmembrane protein 206
TMEM212 transmembrane protein 212
UNC13A unc-13 homolog A (C. elegans)
VNN1 vanin 1
ZNF747 zinc finger protein 747
ZNF749 zinc finger protein 749
ZXDB zinc finger, X-linked, duplicated B