nafcillin-3323 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the nafcillin-3323 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ARSD arylsulfatase D
ASB1 ankyrin repeat and SOCS box containing 1
ATG3 autophagy related 3
ATN1 atrophin 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
B9D2 B9 protein domain 2
BCAM basal cell adhesion molecule (Lutheran blood group)
BIN1 bridging integrator 1
C21ORF2 chromosome 21 open reading frame 2
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCDC40 coiled-coil domain containing 40
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CLGN calmegin
COL4A1 collagen, type IV, alpha 1
COL6A2 collagen, type VI, alpha 2
COPZ2 coatomer protein complex, subunit zeta 2
CTSF cathepsin F
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DGKQ diacylglycerol kinase, theta 110kDa
DHRS7 dehydrogenase/reductase (SDR family) member 7
DRD2 dopamine receptor D2
EFR3B EFR3 homolog B (S. cerevisiae)
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELL2 elongation factor, RNA polymerase II, 2
EXT1 exostosin glycosyltransferase 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FSCN3 fascin actin-bundling protein 3, testicular
GFER growth factor, augmenter of liver regeneration
GRK4 G protein-coupled receptor kinase 4
HABP4 hyaluronan binding protein 4
HFE hemochromatosis
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC4 homeobox C4
IGFBP5 insulin-like growth factor binding protein 5
IL5RA interleukin 5 receptor, alpha
INHBA inhibin, beta A
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNK10 potassium channel, two pore domain subfamily K, member 10
KIAA0125 KIAA0125
KRT6B keratin 6B, type II
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NADK NAD kinase
NDRG2 NDRG family member 2
NME5 NME/NM23 family member 5
NOL10 nucleolar protein 10
NOVA2 neuro-oncological ventral antigen 2
NPR3 natriuretic peptide receptor 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OXCT2 3-oxoacid CoA transferase 2
PARD6B par-6 family cell polarity regulator beta
PAX5 paired box 5
PCDH1 protocadherin 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PIGR polymeric immunoglobulin receptor
PLXNB3 plexin B3
PLXNC1 plexin C1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PVRL3 poliovirus receptor-related 3
RAB33A RAB33A, member RAS oncogene family
RAB3B RAB3B, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RETN resistin
RHEB Ras homolog enriched in brain
RPS28 ribosomal protein S28
RUFY3 RUN and FYVE domain containing 3
RUNX1 runt-related transcription factor 1
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIRT5 sirtuin 5
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC35E2 solute carrier family 35, member E2
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SPTBN1 spectrin, beta, non-erythrocytic 1
SSX1 synovial sarcoma, X breakpoint 1
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
TAOK2 TAO kinase 2
TEF thyrotrophic embryonic factor
TMEM63A transmembrane protein 63A
TNC tenascin C
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TTC38 tetratricopeptide repeat domain 38
UBXN1 UBX domain protein 1
USP46 ubiquitin specific peptidase 46
WFDC2 WAP four-disulfide core domain 2
XIST X inactive specific transcript (non-protein coding)
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF552 zinc finger protein 552
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAM15 ADAM metallopeptidase domain 15
ADAP2 ArfGAP with dual PH domains 2
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANP32A-IT1 ANP32A intronic transcript 1
ANXA2P3 annexin A2 pseudogene 3
ARHGAP11A Rho GTPase activating protein 11A
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
C19ORF73 chromosome 19 open reading frame 73
C5AR2 complement component 5a receptor 2
CCP110 centriolar coiled coil protein 110kDa
CENPJ centromere protein J
CLCN5 chloride channel, voltage-sensitive 5
CLDND1 claudin domain containing 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCP1A decapping mRNA 1A
DDIT3 DNA-damage-inducible transcript 3
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENO3 enolase 3 (beta, muscle)
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
EXOC6B exocyst complex component 6B
FGD1 FYVE, RhoGEF and PH domain containing 1
FLCN folliculin
GEMIN8 gem (nuclear organelle) associated protein 8
GINS4 GINS complex subunit 4 (Sld5 homolog)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HCAR3 hydroxycarboxylic acid receptor 3
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HIST1H2AI histone cluster 1, H2ai
HIST1H2AL histone cluster 1, H2al
HIST1H4F histone cluster 1, H4f
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC10 homeobox C10
HOXC5 homeobox C5
HSPA1L heat shock 70kDa protein 1-like
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL4R interleukin 4 receptor
IRF9 interferon regulatory factor 9
KCNK12 potassium channel, two pore domain subfamily K, member 12
LPXN leupaxin
LRRC37A3 leucine rich repeat containing 37, member A3
MAST3 microtubule associated serine/threonine kinase 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCOLN1 mucolipin 1
N4BP3 NEDD4 binding protein 3
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NPY5R neuropeptide Y receptor Y5
NXPH4 neurexophilin 4
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PCDHA6 protocadherin alpha 6
PCDHGB5 protocadherin gamma subfamily B, 5
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCD1 phospholipase C, delta 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRR14L proline rich 14-like
RAB30 RAB30, member RAS oncogene family
RNF146 ring finger protein 146
ROM1 retinal outer segment membrane protein 1
RPGRIP1L RPGRIP1-like
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A9 S100 calcium binding protein A9
SCN1B sodium channel, voltage gated, type I beta subunit
SIRAL2 SIR2 antiphage like 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D2 TBC1 domain family, member 2
THBS3 thrombospondin 3
TMEM209 transmembrane protein 209
TMEM242 transmembrane protein 242
TMEM254 transmembrane protein 254
TPCN1 two pore segment channel 1
TRAF2 TNF receptor-associated factor 2
TTLL1 tubulin tyrosine ligase-like family member 1
ULBP2 UL16 binding protein 2
USB1 U6 snRNA biogenesis 1
VLDLR very low density lipoprotein receptor
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
WDR91 WD repeat domain 91
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF134 zinc finger protein 134
ZNF350 zinc finger protein 350
ZNF586 zinc finger protein 586
ZNF652 zinc finger protein 652