nafcillin-3983 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the nafcillin-3983 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADAM23 ADAM metallopeptidase domain 23
ALOX5 arachidonate 5-lipoxygenase
AQP3 aquaporin 3 (Gill blood group)
ARTN artemin
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BEND5 BEN domain containing 5
BMP5 bone morphogenetic protein 5
BTBD18 BTB (POZ) domain containing 18
C19ORF26 chromosome 19 open reading frame 26
C8ORF44 chromosome 8 open reading frame 44
CA5B carbonic anhydrase VB, mitochondrial
CACFD1 calcium channel flower domain containing 1
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC186 coiled-coil domain containing 186
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CELF2 CUGBP, Elav-like family member 2
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRAT carnitine O-acetyltransferase
CRY2 cryptochrome circadian clock 2
DAPK1 death-associated protein kinase 1
DGCR6L DiGeorge syndrome critical region gene 6-like
DOCK6 dedicator of cytokinesis 6
EPHA5 EPH receptor A5
FAS Fas cell surface death receptor
FBXO31 F-box protein 31
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FRMD1 FERM domain containing 1
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GFI1 growth factor independent 1 transcription repressor
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR135 G protein-coupled receptor 135
HFE hemochromatosis
HNF1B HNF1 homeobox B
IFFO1 intermediate filament family orphan 1
KRT4 keratin 4, type II
LIMD1 LIM domains containing 1
LINC00115 long intergenic non-protein coding RNA 115
LOC157562 uncharacterized LOC157562
LOXL3 lysyl oxidase-like 3
LTB4R leukotriene B4 receptor
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAPK11 mitogen-activated protein kinase 11
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTRF1L mitochondrial translational release factor 1-like
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCAM1 neural cell adhesion molecule 1
NCF4 neutrophil cytosolic factor 4, 40kDa
NEU3 sialidase 3 (membrane sialidase)
NFX1 nuclear transcription factor, X-box binding 1
NPR1 natriuretic peptide receptor 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NRF1 nuclear respiratory factor 1
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OSBPL10 oxysterol binding protein-like 10
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PITX2 paired-like homeodomain 2
PLCD1 phospholipase C, delta 1
PLN phospholamban
PLXND1 plexin D1
PPARD peroxisome proliferator-activated receptor delta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRPH2 peripherin 2 (retinal degeneration, slow)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRB protein tyrosine phosphatase, receptor type, B
PTPRF protein tyrosine phosphatase, receptor type, F
QPCT glutaminyl-peptide cyclotransferase
RAB6A RAB6A, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RIC3 RIC3 acetylcholine receptor chaperone
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A12 S100 calcium binding protein A12
SCAF4 SR-related CTD-associated factor 4
SGSM3 small G protein signaling modulator 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SOCS3 suppressor of cytokine signaling 3
SPATA2L spermatogenesis associated 2-like
SPP1 secreted phosphoprotein 1
STAT2 signal transducer and activator of transcription 2, 113kDa
TFCP2L1 transcription factor CP2-like 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMC6 transmembrane channel-like 6
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TTC30A tetratricopeptide repeat domain 30A
TTLL4 tubulin tyrosine ligase-like family member 4
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZHX3 zinc fingers and homeoboxes 3
ZNF224 zinc finger protein 224
ZNF334 zinc finger protein 334

decreased expression

Symbol Name
AGO4 argonaute RISC catalytic component 4
ALOX12 arachidonate 12-lipoxygenase
ALOX15B arachidonate 15-lipoxygenase, type B
ANKRD36 ankyrin repeat domain 36
ARHGAP22 Rho GTPase activating protein 22
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARPIN actin-related protein 2/3 complex inhibitor
BATF3 basic leucine zipper transcription factor, ATF-like 3
C17ORF53 chromosome 17 open reading frame 53
C19ORF40 chromosome 19 open reading frame 40
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCNJL cyclin J-like
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDON cell adhesion associated, oncogene regulated
CENPJ centromere protein J
CHI3L2 chitinase 3-like 2
CIDEB cell death-inducing DFFA-like effector b
CORO1A coronin, actin binding protein, 1A
CPNE7 copine VII
CRMP1 collapsin response mediator protein 1
CRYBA2 crystallin, beta A2
DCAF13 DDB1 and CUL4 associated factor 13
DDN dendrin
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
EDN1 endothelin 1
EPN1 epsin 1
EXOC6B exocyst complex component 6B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF23 fibroblast growth factor 23
FRS3 fibroblast growth factor receptor substrate 3
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GRAMD1C GRAM domain containing 1C
GTF2I general transcription factor IIi
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HINFP histone H4 transcription factor
HIST1H1E histone cluster 1, H1e
HIST1H3B histone cluster 1, H3b
HSPA1L heat shock 70kDa protein 1-like
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFNA14 interferon, alpha 14
IL12RB1 interleukin 12 receptor, beta 1
IL17RB interleukin 17 receptor B
IREB2 iron-responsive element binding protein 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KLHL28 kelch-like family member 28
LINS lines homolog (Drosophila)
LRRC61 leucine rich repeat containing 61
LRRK1 leucine-rich repeat kinase 1
LY6D lymphocyte antigen 6 complex, locus D
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MMP10 matrix metallopeptidase 10
MN1 meningioma (disrupted in balanced translocation) 1
MNMIP1 manchette microtubule inner protein 1
MXD3 MAX dimerization protein 3
MYL9 myosin, light chain 9, regulatory
NBEAL2 neurobeachin-like 2
NIPAL2 NIPA-like domain containing 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PACS1 phosphofurin acidic cluster sorting protein 1
PIP prolactin-induced protein
POMT2 protein-O-mannosyltransferase 2
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRSS53 protease, serine, 53
RAB17 RAB17, member RAS oncogene family
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RIN1 Ras and Rab interactor 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SAYSD1 SAYSVFN motif domain containing 1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SSTR4 somatostatin receptor 4
STAG3 stromal antigen 3
STEAP4 STEAP family member 4
TAGLN3 transgelin 3
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNRC6B trinucleotide repeat containing 6B
TRPM4 transient receptor potential cation channel, subfamily M, member 4
WNT1 wingless-type MMTV integration site family, member 1
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF428 zinc finger protein 428
ZNF528 zinc finger protein 528
ZNF747 zinc finger protein 747