nafcillin-4103 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the nafcillin-4103 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACTC1 actin, alpha, cardiac muscle 1
ACTN2 actinin, alpha 2
ADAP2 ArfGAP with dual PH domains 2
ADCK2 aarF domain containing kinase 2
ADGRA2 adhesion G protein-coupled receptor A2
ALK anaplastic lymphoma receptor tyrosine kinase
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP25 Rho GTPase activating protein 25
ASPH aspartate beta-hydroxylase
BARX2 BARX homeobox 2
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CADM4 cell adhesion molecule 4
CAMK4 calcium/calmodulin-dependent protein kinase IV
CARD9 caspase recruitment domain family, member 9
CCDC177 coiled-coil domain containing 177
CCL27 chemokine (C-C motif) ligand 27
CCND2 cyclin D2
CD8A CD8a molecule
CDC14A cell division cycle 14A
CLIC2 chloride intracellular channel 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCN decorin
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DZIP3 DAZ interacting zinc finger protein 3
EPHB1 EPH receptor B1
ETV5 ets variant 5
FCAR Fc fragment of IgA receptor
FGF16 fibroblast growth factor 16
FLOT1 flotillin 1
GAS7 growth arrest-specific 7
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GGT1 gamma-glutamyltransferase 1
GK2 glycerol kinase 2
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
HPGDS hematopoietic prostaglandin D synthase
HPX hemopexin
ICA1 islet cell autoantigen 1, 69kDa
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1RAP interleukin 1 receptor accessory protein
ING2 inhibitor of growth family, member 2
INHBA inhibin, beta A
IPW imprinted in Prader-Willi syndrome (non-protein coding)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIAA1045 KIAA1045
KLHL25 kelch-like family member 25
LAMA4 laminin, alpha 4
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMX1B LIM homeobox transcription factor 1, beta
LPL lipoprotein lipase
MAOB monoamine oxidase B
MAPK7 mitogen-activated protein kinase 7
MCTP2 multiple C2 domains, transmembrane 2
MTL5 metallothionein-like 5, testis-specific (tesmin)
MX1 MX dynamin-like GTPase 1
MYEF2 myelin expression factor 2
NOVA2 neuro-oncological ventral antigen 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PAPPA2 pappalysin 2
PCNX pecanex homolog (Drosophila)
PLA2G3 phospholipase A2, group III
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRB1 proline-rich protein BstNI subfamily 1
PRMT2IP PRMT2 interacting protein
PTK2B protein tyrosine kinase 2 beta
RASIP1 Ras interacting protein 1
RERE arginine-glutamic acid dipeptide (RE) repeats
RGS10 regulator of G-protein signaling 10
RHBG Rh family, B glycoprotein (gene/pseudogene)
SAG S-antigen; retina and pineal gland (arrestin)
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SH3BP2 SH3-domain binding protein 2
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SNCAIP synuclein, alpha interacting protein
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SYNDIG1 synapse differentiation inducing 1
TEX14 testis expressed 14
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TM4SF20 transmembrane 4 L six family member 20
TMOD1 tropomodulin 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSPAN9 tetraspanin 9
TUBGCP2 tubulin, gamma complex associated protein 2
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UHRF1BP1L UHRF1 binding protein 1-like
VCAN versican
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZNF3 zinc finger protein 3
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC6 armadillo repeat containing 6
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAGE B melanoma antigen
BMP4 bone morphogenetic protein 4
C7ORF43 chromosome 7 open reading frame 43
CAPN5 calpain 5
CAPRIN2 caprin family member 2
CARD8 caspase recruitment domain family, member 8
CCDC69 coiled-coil domain containing 69
CLSTN2 calsyntenin 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGAT1 diacylglycerol O-acyltransferase 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ELP6 elongator acetyltransferase complex subunit 6
EPHA2 EPH receptor A2
ETV6 ets variant 6
EXD3 exonuclease 3'-5' domain containing 3
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL6 F-box and leucine-rich repeat protein 6
FBXL7 F-box and leucine-rich repeat protein 7
FKBP10 FK506 binding protein 10, 65 kDa
FUZ fuzzy planar cell polarity protein
GAMT guanidinoacetate N-methyltransferase
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPX2 glutathione peroxidase 2
GRPR gastrin-releasing peptide receptor
HIST1H1D histone cluster 1, H1d
HIST1H3E histone cluster 1, H3e
HMOX1 heme oxygenase 1
HOXC5 homeobox C5
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IL4R interleukin 4 receptor
INO80D INO80 complex subunit D
INPP5J inositol polyphosphate-5-phosphatase J
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KLF3 Kruppel-like factor 3 (basic)
KLHL21 kelch-like family member 21
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LOXL1 lysyl oxidase-like 1
LRP5L low density lipoprotein receptor-related protein 5-like
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MCOLN1 mucolipin 1
MCRS1 microspherule protein 1
MFAP2 microfibrillar-associated protein 2
MVD mevalonate (diphospho) decarboxylase
MYO19 myosin XIX
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NAT6 N-acetyltransferase 6 (GCN5-related)
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
POMT2 protein-O-mannosyltransferase 2
RAB30 RAB30, member RAS oncogene family
RAI2 retinoic acid induced 2
RLN1 relaxin 1
RNF122 ring finger protein 122
ROM1 retinal outer segment membrane protein 1
RPL10L ribosomal protein L10-like
S100A6 S100 calcium binding protein A6
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNTA1 syntrophin, alpha 1
STK16 serine/threonine kinase 16
TBC1D17 TBC1 domain family, member 17
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
THBS3 thrombospondin 3
TNS2 tensin 2
TRABD TraB domain containing
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UPK2 uroplakin 2
WFDC2 WAP four-disulfide core domain 2
ZNF134 zinc finger protein 134
ZNF280A zinc finger protein 280A
ZNF34 zinc finger protein 34
ZNF37BP zinc finger protein 37B, pseudogene