naftidrofuryl-2622 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the naftidrofuryl-2622 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABHD2 abhydrolase domain containing 2
ACBD4 acyl-CoA binding domain containing 4
ADORA3 adenosine A3 receptor
ADRA1A adrenoceptor alpha 1A
AKAP7 A kinase (PRKA) anchor protein 7
ALOX5 arachidonate 5-lipoxygenase
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARID1A AT rich interactive domain 1A (SWI-like)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCL2L1 BCL2-like 1
BTN3A1 butyrophilin, subfamily 3, member A1
C10ORF95 chromosome 10 open reading frame 95
C1ORF105 chromosome 1 open reading frame 105
CA1 carbonic anhydrase I
CA5B carbonic anhydrase VB, mitochondrial
CA9 carbonic anhydrase IX
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCKAR cholecystokinin A receptor
CCL21 chemokine (C-C motif) ligand 21
CD6 CD6 molecule
CDON cell adhesion associated, oncogene regulated
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CNOT2 CCR4-NOT transcription complex, subunit 2
CROCC ciliary rootlet coiled-coil, rootletin
CRYGD crystallin, gamma D
DUSP2 dual specificity phosphatase 2
DVL3 dishevelled segment polarity protein 3
EHBP1L1 EH domain binding protein 1-like 1
ETV7 ets variant 7
FAM182B family with sequence similarity 182, member B
FBXL2 F-box and leucine-rich repeat protein 2
FGF16 fibroblast growth factor 16
FGFBP1 fibroblast growth factor binding protein 1
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GIMAP5 GTPase, IMAP family member 5
GM2A GM2 ganglioside activator
GNAS GNAS complex locus
GPR182 G protein-coupled receptor 182
GRM2 glutamate receptor, metabotropic 2
HDAC5 histone deacetylase 5
IGF2-AS IGF2 antisense RNA
IGFBP3 insulin-like growth factor binding protein 3
IQSEC2 IQ motif and Sec7 domain 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM4C lysine (K)-specific demethylase 4C
KLK5 kallikrein-related peptidase 5
KRT24 keratin 24, type I
LBP lipopolysaccharide binding protein
LGALS9 lectin, galactoside-binding, soluble, 9
LHB luteinizing hormone beta polypeptide
LINC00574 long intergenic non-protein coding RNA 574
LOC100131532 uncharacterized LOC100131532
LTC4S leukotriene C4 synthase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARK4 MAP/microtubule affinity-regulating kinase 4
MCF2L MCF.2 cell line derived transforming sequence-like
MFAP3L microfibrillar-associated protein 3-like
MINK1 misshapen-like kinase 1
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYF5 myogenic factor 5
NMT2 N-myristoyltransferase 2
NPY neuropeptide Y
NRF1 nuclear respiratory factor 1
OGFR opioid growth factor receptor
OR3A3 olfactory receptor, family 3, subfamily A, member 3
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHB8 protocadherin beta 8
PDE4DIP phosphodiesterase 4D interacting protein
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLAC4 placenta-specific 4
POMT2 protein-O-mannosyltransferase 2
POU2F2 POU class 2 homeobox 2
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PSG6 pregnancy specific beta-1-glycoprotein 6
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SEC24D SEC24 family member D
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SNX13 sorting nexin 13
SPINK1 serine peptidase inhibitor, Kazal type 1
STAC SH3 and cysteine rich domain
STK11 serine/threonine kinase 11
TBL2 transducin (beta)-like 2
TLR4 toll-like receptor 4
TP53I11 tumor protein p53 inducible protein 11
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
WDR61 WD repeat domain 61
ZC3H13 zinc finger CCCH-type containing 13
ZFHX2 zinc finger homeobox 2
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF230 zinc finger protein 230
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ACOX3 acyl-CoA oxidase 3, pristanoyl
ADM adrenomedullin
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCAS1 breast carcinoma amplified sequence 1
BMP4 bone morphogenetic protein 4
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C11ORF30 chromosome 11 open reading frame 30
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC47 coiled-coil domain containing 47
CD79B CD79b molecule, immunoglobulin-associated beta
CDK3 cyclin-dependent kinase 3
CEP72 centrosomal protein 72kDa
CGA glycoprotein hormones, alpha polypeptide
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLCN5 chloride channel, voltage-sensitive 5
CLDN15 claudin 15
COG4 component of oligomeric golgi complex 4
CORO2A coronin, actin binding protein, 2A
CUTC cutC copper transporter
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DUSP5 dual specificity phosphatase 5
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM53B family with sequence similarity 53, member B
FBXO31 F-box protein 31
FKBP5 FK506 binding protein 5
FLRT3 fibronectin leucine rich transmembrane protein 3
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GDAP1 ganglioside induced differentiation associated protein 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L2 galactosidase, beta 1-like 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRWD1 glutamate-rich WD repeat containing 1
HIST1H2BI histone cluster 1, H2bi
HOOK1 hook microtubule-tethering protein 1
HOXC10 homeobox C10
HP1BP3 heterochromatin protein 1, binding protein 3
HPSE heparanase
IFI35 interferon-induced protein 35
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM5C lysine (K)-specific demethylase 5C
KIAA0895 KIAA0895
LRP5 low density lipoprotein receptor-related protein 5
MFSD11 major facilitator superfamily domain containing 11
MTCL1 microtubule crosslinking factor 1
MVD mevalonate (diphospho) decarboxylase
NEK11 NIMA-related kinase 11
NOTCH1 notch 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PADI1 peptidyl arginine deiminase, type I
PDIA3 protein disulfide isomerase family A, member 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PIBF1 progesterone immunomodulatory binding factor 1
PKN1 protein kinase N1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
PRR14L proline rich 14-like
PTCD2 pentatricopeptide repeat domain 2
PUS1 pseudouridylate synthase 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RFX7 regulatory factor X, 7
RGS17 regulator of G-protein signaling 17
RIBC2 RIB43A domain with coiled-coils 2
RNF122 ring finger protein 122
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL13P5 ribosomal protein L13 pseudogene 5
SGPP1 sphingosine-1-phosphate phosphatase 1
SHARPIN SHANK-associated RH domain interactor
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRYD7 SPRY domain containing 7
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TICAM1 toll-like receptor adaptor molecule 1
TMEM180 transmembrane protein 180
TMEM62 transmembrane protein 62
TRIM25 tripartite motif containing 25
TSPYL2 TSPY-like 2
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
ULBP2 UL16 binding protein 2
USB1 U6 snRNA biogenesis 1
VAX2 ventral anterior homeobox 2
WDR46 WD repeat domain 46
XAB2 XPA binding protein 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF668 zinc finger protein 668