| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the naftifine-2974 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY9 | adenylate cyclase 9 |
| AK1 | adenylate kinase 1 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ANTXR1 | anthrax toxin receptor 1 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| AXIN1 | axin 1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BTD | biotinidase |
| C6ORF106 | chromosome 6 open reading frame 106 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAT | catalase |
| CCR9 | chemokine (C-C motif) receptor 9 |
| CEP164 | centrosomal protein 164kDa |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CNTN1 | contactin 1 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CUX1 | cut-like homeobox 1 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DZIP3 | DAZ interacting zinc finger protein 3 |
| ENG | endoglin |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPHB2 | EPH receptor B2 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GSDMB | gasdermin B |
| HIST1H3G | histone cluster 1, H3g |
| HNMT | histamine N-methyltransferase |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| HOXA5 | homeobox A5 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL6ST | interleukin 6 signal transducer |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| IZUMO4 | IZUMO family member 4 |
| KHK | ketohexokinase (fructokinase) |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LTB4R | leukotriene B4 receptor |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MMP25 | matrix metallopeptidase 25 |
| MPDZ | multiple PDZ domain protein |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MYBPH | myosin binding protein H |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NEUROD4 | neuronal differentiation 4 |
| NLRP3 | NLR family, pyrin domain containing 3 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| PDE12 | phosphodiesterase 12 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PHF3 | PHD finger protein 3 |
| PLAT | plasminogen activator, tissue |
| PLCD1 | phospholipase C, delta 1 |
| PQLC2 | PQ loop repeat containing 2 |
| PTAFR | platelet-activating factor receptor |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RGS5 | regulator of G-protein signaling 5 |
| RPL13 | ribosomal protein L13 |
| RUNX1 | runt-related transcription factor 1 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SFTPB | surfactant protein B |
| SH2D3A | SH2 domain containing 3A |
| SIRT4 | sirtuin 4 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMAD3 | SMAD family member 3 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| TCP10L | t-complex 10-like |
| THBS3 | thrombospondin 3 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TMEM19 | transmembrane protein 19 |
| TOP3B | topoisomerase (DNA) III beta |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZNF492 | zinc finger protein 492 |
| ZNF512B | zinc finger protein 512B |
| ZNF609 | zinc finger protein 609 |
| ZNF747 | zinc finger protein 747 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| ALS2CL | ALS2 C-terminal like |
| APOBR | apolipoprotein B receptor |
| ARHGAP11A | Rho GTPase activating protein 11A |
| BBS10 | Bardet-Biedl syndrome 10 |
| BCORL1 | BCL6 corepressor-like 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CD101 | CD101 molecule |
| CD320 | CD320 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CES3 | carboxylesterase 3 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLGN | calmegin |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DUSP4 | dual specificity phosphatase 4 |
| EDC4 | enhancer of mRNA decapping 4 |
| ENAH | enabled homolog (Drosophila) |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FER | fer (fps/fes related) tyrosine kinase |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| FZD2 | frizzled class receptor 2 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLCE | glucuronic acid epimerase |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GSTA4 | glutathione S-transferase alpha 4 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| IFNA14 | interferon, alpha 14 |
| IL11RA | interleukin 11 receptor, alpha |
| IL24 | interleukin 24 |
| IRF7 | interferon regulatory factor 7 |
| KIAA0319L | KIAA0319-like |
| KIAA0754 | KIAA0754 |
| KIF13B | kinesin family member 13B |
| KIF3B | kinesin family member 3B |
| LIMD2 | LIM domain containing 2 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MANSC1 | MANSC domain containing 1 |
| MAP1S | microtubule-associated protein 1S |
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| METTL2B | methyltransferase like 2B |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MX1 | MX dynamin-like GTPase 1 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NOTCH1 | notch 1 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PKN1 | protein kinase N1 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PRAF2 | PRA1 domain family, member 2 |
| PROCR | protein C receptor, endothelial |
| RAB23 | RAB23, member RAS oncogene family |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RFXAP | regulatory factor X-associated protein |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RGS13 | regulator of G-protein signaling 13 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF144A | ring finger protein 144A |
| RNF2 | ring finger protein 2 |
| RNF31 | ring finger protein 31 |
| RUSC2 | RUN and SH3 domain containing 2 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SCAI | suppressor of cancer cell invasion |
| SGCE | sarcoglycan, epsilon |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| STBD1 | starch binding domain 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
| SUSD6 | sushi domain containing 6 |
| TBX19 | T-box 19 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM242 | transmembrane protein 242 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRIM9 | tripartite motif containing 9 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZNF506 | zinc finger protein 506 |
