naftifine-7032 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the naftifine-7032 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ADAM17 ADAM metallopeptidase domain 17
ADGRE5 adhesion G protein-coupled receptor E5
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ARHGAP33 Rho GTPase activating protein 33
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BLZF1 basic leucine zipper nuclear factor 1
BRD4 bromodomain containing 4
C8A complement component 8, alpha polypeptide
CCNG2 cyclin G2
CCPG1 cell cycle progression 1
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHD3 chromodomain helicase DNA binding protein 3
CLIC2 chloride intracellular channel 2
CRELD1 cysteine-rich with EGF-like domains 1
CSTA cystatin A (stefin A)
CUL7 cullin 7
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
EDAR ectodysplasin A receptor
EHD1 EH-domain containing 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FBXO11 F-box protein 11
FRMD4B FERM domain containing 4B
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GAST gastrin
GRSF1 G-rich RNA sequence binding factor 1
HAMP hepcidin antimicrobial peptide
HMOX1 heme oxygenase 1
HSF1 heat shock transcription factor 1
ICAM1 intercellular adhesion molecule 1
IFT38 intraflagellar transport 38
INHBE inhibin, beta E
INTS7 integrator complex subunit 7
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
JUNB jun B proto-oncogene
LARP6 La ribonucleoprotein domain family, member 6
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1B microtubule-associated protein 1B
MAP2K5 mitogen-activated protein kinase kinase 5
MBNL2 muscleblind-like splicing regulator 2
MCM3AP minichromosome maintenance complex component 3 associated protein
MIP major intrinsic protein of lens fiber
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MXD4 MAX dimerization protein 4
NASP nuclear autoantigenic sperm protein (histone-binding)
NDE1 nudE neurodevelopment protein 1
NDN necdin, melanoma antigen (MAGE) family member
NEB nebulin
NFIL3 nuclear factor, interleukin 3 regulated
NPIPB15 nuclear pore complex interacting protein family, member B15
NR2C1 nuclear receptor subfamily 2, group C, member 1
NUPR1 nuclear protein, transcriptional regulator, 1
OASL 2'-5'-oligoadenylate synthetase-like
OR10H1 olfactory receptor, family 10, subfamily H, member 1
PAIP2B poly(A) binding protein interacting protein 2B
PDGFB platelet-derived growth factor beta polypeptide
PHF3 PHD finger protein 3
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLAGL1 pleiomorphic adenoma gene-like 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
POM121 POM121 transmembrane nucleoporin
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRKCA protein kinase C, alpha
PTCH1 patched 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB40A RAB40A, member RAS oncogene family
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPGR retinitis pigmentosa GTPase regulator
RUFY2 RUN and FYVE domain containing 2
SAMD9 sterile alpha motif domain containing 9
SAV1 salvador family WW domain containing protein 1
SCAMP1 secretory carrier membrane protein 1
SCGB2A2 secretoglobin, family 2A, member 2
SH2B3 SH2B adaptor protein 3
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SPRR1A small proline-rich protein 1A
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TCP11 t-complex 11, testis-specific
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIB3 tribbles pseudokinase 3
USP34 ubiquitin specific peptidase 34
VEGFA vascular endothelial growth factor A
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
ADGRA3 adhesion G protein-coupled receptor A3
AGO1 argonaute RISC catalytic component 1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANKRD28 ankyrin repeat domain 28
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASB6 ankyrin repeat and SOCS box containing 6
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
B3GNT1
C1ORF115 chromosome 1 open reading frame 115
C1ORF35 chromosome 1 open reading frame 35
C9ORF40 chromosome 9 open reading frame 40
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC15 coiled-coil domain containing 15
CCDC88C coiled-coil domain containing 88C
CENPC centromere protein C
COL4A5 collagen, type IV, alpha 5
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DUSP5 dual specificity phosphatase 5
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
FCHO1 FCH domain only 1
FHOD1 formin homology 2 domain containing 1
FRS2 fibroblast growth factor receptor substrate 2
GALK1 galactokinase 1
GHR growth hormone receptor
GJA1 gap junction protein, alpha 1, 43kDa
GLCE glucuronic acid epimerase
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSPA2 heat shock 70kDa protein 2
INCENP inner centromere protein antigens 135/155kDa
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IQSEC2 IQ motif and Sec7 domain 2
IREB2 iron-responsive element binding protein 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KLHL26 kelch-like family member 26
LIN7B lin-7 homolog B (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LOC390998 ribosomal protein L10 pseudogene
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRP3 low density lipoprotein receptor-related protein 3
LRRC61 leucine rich repeat containing 61
LYPD1 LY6/PLAUR domain containing 1
MANEA mannosidase, endo-alpha
MBOAT2 membrane bound O-acyltransferase domain containing 2
MICALL2 MICAL-like 2
MLYCD malonyl-CoA decarboxylase
MNS1 meiosis-specific nuclear structural 1
MNX1 motor neuron and pancreas homeobox 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYO1D myosin ID
NES nestin
NHEJ1 nonhomologous end-joining factor 1
NPY1R neuropeptide Y receptor Y1
PBLD phenazine biosynthesis-like protein domain containing
PCDHA6 protocadherin alpha 6
PCDHB3 protocadherin beta 3
PGP phosphoglycolate phosphatase
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIBF1 progesterone immunomodulatory binding factor 1
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKX protein kinase, X-linked
PROCR protein C receptor, endothelial
PTDSS2 phosphatidylserine synthase 2
RAD51AP1 RAD51 associated protein 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RCOR3 REST corepressor 3
RGS19 regulator of G-protein signaling 19
RHOB ras homolog family member B
SACS sacsin molecular chaperone
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SREBF1 sterol regulatory element binding transcription factor 1
SSFA2 sperm specific antigen 2
STAG3 stromal antigen 3
STARD13 StAR-related lipid transfer (START) domain containing 13
TBC1D12 TBC1 domain family, member 12
TEAD3 TEA domain family member 3
TMEM62 transmembrane protein 62
TRIM5 tripartite motif containing 5
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTI2 TELO2 interacting protein 2
TUBA3C tubulin, alpha 3c
URGCP upregulator of cell proliferation
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XYLT2 xylosyltransferase II
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF219 zinc finger protein 219
ZNF654 zinc finger protein 654
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF8 zinc finger protein 8